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Items: 1 to 20 of 169

1.

Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6.

Truksa J, Gelbart T, Peng H, Beutler E, Beutler B, Lee P.

Br J Haematol. 2009 Nov;147(4):571-81. doi: 10.1111/j.1365-2141.2009.07873.x. Epub 2009 Sep 8.

PMID:
19751239
2.

Liver hemojuvelin protein levels in mice deficient in matriptase-2 (Tmprss6).

Krijt J, Fujikura Y, Ramsay AJ, Velasco G, Nečas E.

Blood Cells Mol Dis. 2011 Aug 15;47(2):133-7. doi: 10.1016/j.bcmd.2011.04.009. Epub 2011 May 25.

PMID:
21612955
3.

Effect of erythropoietin on hepcidin expression in hemojuvelin-mutant mice.

Krijt J, Jonásová A, Neuwirtová R, Necas E.

Blood Cells Mol Dis. 2010 Apr 15;44(4):257-61. doi: 10.1016/j.bcmd.2010.02.012. Epub 2010 Mar 12.

PMID:
20219396
4.

Retinal expression of the serine protease matriptase-2 (Tmprss6) and its role in retinal iron homeostasis.

Gnana-Prakasam JP, Baldowski RB, Ananth S, Martin PM, Smith SB, Ganapathy V.

Mol Vis. 2014 Apr 26;20:561-74. eCollection 2014.

5.

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis.

Folgueras AR, de Lara FM, Pendás AM, Garabaya C, Rodríguez F, Astudillo A, Bernal T, Cabanillas R, López-Otín C, Velasco G.

Blood. 2008 Sep 15;112(6):2539-45. doi: 10.1182/blood-2008-04-149773. Epub 2008 Jun 3.

6.

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6.

Lenoir A, Deschemin JC, Kautz L, Ramsay AJ, Roth MP, Lopez-Otin C, Vaulont S, Nicolas G.

Blood. 2011 Jan 13;117(2):647-50. doi: 10.1182/blood-2010-07-295147. Epub 2010 Oct 12.

7.

Into the matrix: regulation of the iron regulatory hormone hepcidin by matriptase-2.

Knutson MD.

Nutr Rev. 2009 May;67(5):284-8. doi: 10.1111/j.1753-4887.2009.00200.x. Review.

PMID:
19386032
8.

Decreased hemojuvelin protein levels in mask mice lacking matriptase-2-dependent proteolytic activity.

Frýdlová J, Fujikura Y, Vokurka M, Nečas E, Krijt J.

Physiol Res. 2013;62(4):405-11. Epub 2013 Apr 16.

9.

Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin.

Lin L, Goldberg YP, Ganz T.

Blood. 2005 Oct 15;106(8):2884-9. Epub 2005 Jul 5.

10.

Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.

Nai A, Pagani A, Mandelli G, Lidonnici MR, Silvestri L, Ferrari G, Camaschella C.

Blood. 2012 May 24;119(21):5021-9. doi: 10.1182/blood-2012-01-401885. Epub 2012 Apr 6.

11.

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression.

Mleczko-Sanecka K, Casanovas G, Ragab A, Breitkopf K, Müller A, Boutros M, Dooley S, Hentze MW, Muckenthaler MU.

Blood. 2010 Apr 1;115(13):2657-65. doi: 10.1182/blood-2009-09-238105. Epub 2009 Dec 29.

12.

Fine tuning of hepcidin expression by positive and negative regulators.

Muckenthaler MU.

Cell Metab. 2008 Jul;8(1):1-3. doi: 10.1016/j.cmet.2008.06.009. Review.

13.
14.

Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6.

Lee P, Hsu MH, Welser-Alves J, Peng H.

Blood Cells Mol Dis. 2012 Mar 15;48(3):173-8. doi: 10.1016/j.bcmd.2011.12.005. Epub 2012 Jan 14.

15.

Haematologic data, iron parameters and molecular findings in two new cases of iron-refractory iron deficiency anaemia.

Tchou I, Diepold M, Pilotto PA, Swinkels D, Neerman-Arbez M, Beris P.

Eur J Haematol. 2009 Dec 1;83(6):595-602. doi: 10.1111/j.1600-0609.2009.01340.x. Epub 2009 Aug 25.

PMID:
19708871
16.

Interacting signals in the control of hepcidin expression.

Darshan D, Anderson GJ.

Biometals. 2009 Feb;22(1):77-87. doi: 10.1007/s10534-008-9187-y. Epub 2009 Jan 8.

PMID:
19130266
17.

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin.

Silvestri L, Pagani A, Nai A, De Domenico I, Kaplan J, Camaschella C.

Cell Metab. 2008 Dec;8(6):502-11. doi: 10.1016/j.cmet.2008.09.012. Epub 2008 Oct 30.

18.

Iron-induced expression of bone morphogenic protein 6 in intestinal cells is the main regulator of hepatic hepcidin expression in vivo.

Arndt S, Maegdefrau U, Dorn C, Schardt K, Hellerbrand C, Bosserhoff AK.

Gastroenterology. 2010 Jan;138(1):372-82. doi: 10.1053/j.gastro.2009.09.048. Epub 2009 Sep 26.

PMID:
19786029
19.

Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.

Finberg KE, Whittlesey RL, Fleming MD, Andrews NC.

Blood. 2010 May 6;115(18):3817-26. doi: 10.1182/blood-2009-05-224808. Epub 2010 Mar 3.

20.

Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin.

Krijt J, Fujikura Y, Sefc L, Vokurka M, Hlobenová T, Necas E.

Physiol Res. 2010;59(1):53-9. Epub 2009 Feb 27.

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