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Items: 1 to 20 of 71

1.

Can Sir(2) regulate cancer?

Nerurkar PV, Nerurkar VR.

Cellscience. 2008 Apr 1;4(4):50-56.

2.

Negative regulation of the deacetylase SIRT1 by DBC1.

Zhao W, Kruse JP, Tang Y, Jung SY, Qin J, Gu W.

Nature. 2008 Jan 31;451(7178):587-90. doi: 10.1038/nature06515.

3.

Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase.

Nin V, Escande C, Chini CC, Giri S, Camacho-Pereira J, Matalonga J, Lou Z, Chini EN.

J Biol Chem. 2012 Jul 6;287(28):23489-501. doi: 10.1074/jbc.M112.365874. Epub 2012 May 2.

4.

Sirtuin activators and inhibitors.

Villalba JM, Alcaín FJ.

Biofactors. 2012 Sep-Oct;38(5):349-59. doi: 10.1002/biof.1032. Epub 2012 Jun 25. Review.

5.

Resveratrol delays Wallerian degeneration in a NAD(+) and DBC1 dependent manner.

Calliari A, Bobba N, Escande C, Chini EN.

Exp Neurol. 2014 Jan;251:91-100. doi: 10.1016/j.expneurol.2013.11.013. Epub 2013 Nov 16.

PMID:
24252177
6.

Expression of DBC1 is associated with nuclear grade and HER2 expression in breast cancer.

Hiraike H, Wada-Hiraike O, Nakagawa S, Saji S, Maeda D, Miyamoto Y, Sone K, Tanikawa M, Oda K, Nakagawa K, Yano T, Fukayama M, Taketani Y.

Exp Ther Med. 2011 Nov;2(6):1105-1109. Epub 2011 Aug 12.

7.

DBC1 is a negative regulator of SIRT1.

Kim JE, Chen J, Lou Z.

Nature. 2008 Jan 31;451(7178):583-6. doi: 10.1038/nature06500.

PMID:
18235501
8.

Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice.

Escande C, Chini CC, Nin V, Dykhouse KM, Novak CM, Levine J, van Deursen J, Gores GJ, Chen J, Lou Z, Chini EN.

J Clin Invest. 2010 Feb;120(2):545-58. doi: 10.1172/JCI39319. Epub 2010 Jan 11.

9.

Balance between SIRT1 and DBC1 expression is lost in breast cancer.

Sung JY, Kim R, Kim JE, Lee J.

Cancer Sci. 2010 Jul;101(7):1738-44. doi: 10.1111/j.1349-7006.2010.01573.x. Epub 2010 Mar 24.

10.

DBC1 does not function as a negative regulator of SIRT1 in liver cancer.

Bae HJ, Chang YG, Noh JH, Kim JK, Eun JW, Jung KH, Kim MG, Shen Q, Ahn YM, Kwon SH, Park WS, Lee JY, Nam SW.

Oncol Lett. 2012 Nov;4(5):873-877. Epub 2012 Aug 23.

11.

hMOF acetylation of DBC1/CCAR2 prevents binding and inhibition of SirT1.

Zheng H, Yang L, Peng L, Izumi V, Koomen J, Seto E, Chen J.

Mol Cell Biol. 2013 Dec;33(24):4960-70. doi: 10.1128/MCB.00874-13. Epub 2013 Oct 14.

12.

Reciprocal roles of DBC1 and SIRT1 in regulating estrogen receptor α activity and co-activator synergy.

Yu EJ, Kim SH, Heo K, Ou CY, Stallcup MR, Kim JH.

Nucleic Acids Res. 2011 Sep 1;39(16):6932-43. doi: 10.1093/nar/gkr347. Epub 2011 May 19.

13.

Sirtuin activators.

Alcaín FJ, Villalba JM.

Expert Opin Ther Pat. 2009 Apr;19(4):403-14. doi: 10.1517/13543770902762893. Review.

PMID:
19441923
14.

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.

Menssen A, Hydbring P, Kapelle K, Vervoorts J, Diebold J, Lüscher B, Larsson LG, Hermeking H.

Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):E187-96. doi: 10.1073/pnas.1105304109. Epub 2011 Dec 21.

15.

Identification of DBC1 as a transcriptional repressor for BRCA1.

Hiraike H, Wada-Hiraike O, Nakagawa S, Koyama S, Miyamoto Y, Sone K, Tanikawa M, Tsuruga T, Nagasaka K, Matsumoto Y, Oda K, Shoji K, Fukuhara H, Saji S, Nakagawa K, Kato S, Yano T, Taketani Y.

Br J Cancer. 2010 Mar 16;102(6):1061-7. doi: 10.1038/sj.bjc.6605577. Epub 2010 Feb 16.

16.

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.

Pacholec M, Bleasdale JE, Chrunyk B, Cunningham D, Flynn D, Garofalo RS, Griffith D, Griffor M, Loulakis P, Pabst B, Qiu X, Stockman B, Thanabal V, Varghese A, Ward J, Withka J, Ahn K.

J Biol Chem. 2010 Mar 12;285(11):8340-51. doi: 10.1074/jbc.M109.088682. Epub 2010 Jan 8.

17.

Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma.

Cha EJ, Noh SJ, Kwon KS, Kim CY, Park BH, Park HS, Lee H, Chung MJ, Kang MJ, Lee DG, Moon WS, Jang KY.

Clin Cancer Res. 2009 Jul 1;15(13):4453-9. doi: 10.1158/1078-0432.CCR-08-3329. Epub 2009 Jun 9.

18.

Acetylation status of P53 and the expression of DBC1, SIRT1, and androgen receptor are associated with survival in clear cell renal cell carcinoma patients.

Noh SJ, Kang MJ, Kim KM, Bae JS, Park HS, Moon WS, Chung MJ, Lee H, Lee DG, Jang KY.

Pathology. 2013 Oct;45(6):574-80. doi: 10.1097/PAT.0b013e3283652c7a.

PMID:
24018803
19.

Deleted in breast cancer 1 (DBC1) protein regulates hepatic gluconeogenesis.

Nin V, Chini CC, Escande C, Capellini V, Chini EN.

J Biol Chem. 2014 Feb 28;289(9):5518-27. doi: 10.1074/jbc.M113.512913. Epub 2014 Jan 10.

20.

DBC1 phosphorylation by ATM/ATR inhibits SIRT1 deacetylase in response to DNA damage.

Zannini L, Buscemi G, Kim JE, Fontanella E, Delia D.

J Mol Cell Biol. 2012 Oct;4(5):294-303. doi: 10.1093/jmcb/mjs035. Epub 2012 Jun 26.

PMID:
22735644

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