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Items: 1 to 20 of 93


The tyrosine kinase Fer is a downstream target of the PLD-PA pathway that regulates cell migration.

Itoh T, Hasegawa J, Tsujita K, Kanaho Y, Takenawa T.

Sci Signal. 2009 Sep 8;2(87):ra52. doi: 10.1126/scisignal.2000393.


FES/FER kinase signaling in hematopoietic cells and leukemias.

Craig AW.

Front Biosci (Landmark Ed). 2012 Jan 1;17:861-75. Review.


Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR.

Lehman N, Ledford B, Di Fulvio M, Frondorf K, McPhail LC, Gomez-Cambronero J.

FASEB J. 2007 Apr;21(4):1075-87. Epub 2007 Jan 22.


Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase.

Fan L, Di Ciano-Oliveira C, Weed SA, Craig AW, Greer PA, Rotstein OD, Kapus A.

Biochem J. 2004 Jun 1;380(Pt 2):581-91.


Protein kinase Cdelta-mediated phosphorylation of phospholipase D controls integrin-mediated cell spreading.

Chae YC, Kim KL, Ha SH, Kim J, Suh PG, Ryu SH.

Mol Cell Biol. 2010 Nov;30(21):5086-98. doi: 10.1128/MCB.00443-10. Epub 2010 Aug 23.


A GEF-to-phospholipase molecular switch caused by phosphatidic acid, Rac and JAK tyrosine kinase that explains leukocyte cell migration.

Mahankali M, Henkels KM, Gomez-Cambronero J.

J Cell Sci. 2013 Mar 15;126(Pt 6):1416-28. doi: 10.1242/jcs.117960. Epub 2013 Feb 1.


Dyrk1A negatively regulates the actin cytoskeleton through threonine phosphorylation of N-WASP.

Park J, Sung JY, Park J, Song WJ, Chang S, Chung KC.

J Cell Sci. 2012 Jan 1;125(Pt 1):67-80. doi: 10.1242/jcs.086124. Epub 2012 Jan 16.


Regulation of cytoskeletal dynamics by phospholipase D and phosphatidic acid.

Pleskot R, Li J, Zárský V, Potocký M, Staiger CJ.

Trends Plant Sci. 2013 Sep;18(9):496-504. doi: 10.1016/j.tplants.2013.04.005. Epub 2013 May 7. Review.


Understanding of the roles of phospholipase D and phosphatidic acid through their binding partners.

Jang JH, Lee CS, Hwang D, Ryu SH.

Prog Lipid Res. 2012 Apr;51(2):71-81. doi: 10.1016/j.plipres.2011.12.003. Epub 2011 Dec 28. Review.


Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR).

Foster DA, Salloum D, Menon D, Frias MA.

J Biol Chem. 2014 Aug 15;289(33):22583-8. doi: 10.1074/jbc.R114.566091. Epub 2014 Jul 2. Review.


A non-mitotic role for Aurora kinase A as a direct activator of cell migration upon interaction with PLD, FAK and Src.

Mahankali M, Henkels KM, Speranza F, Gomez-Cambronero J.

J Cell Sci. 2015 Feb 1;128(3):516-26.


Phospholipase D signaling in serotonin-induced mitogenesis of pulmonary artery smooth muscle cells.

Liu Y, Fanburg BL.

Am J Physiol Lung Cell Mol Physiol. 2008 Sep;295(3):L471-8. doi: 10.1152/ajplung.00071.2008. Epub 2008 Jul 11.


G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation.

Majumder S, Sowden MP, Gerber SA, Thomas T, Christie CK, Mohan A, Yin G, Lord EM, Berk BC, Pang J.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):419-26. doi: 10.1161/ATVBAHA.113.302689. Epub 2013 Nov 21.


Transmodulation between phospholipase D and c-Src enhances cell proliferation.

Ahn BH, Kim SY, Kim EH, Choi KS, Kwon TK, Lee YH, Chang JS, Kim MS, Jo YH, Min DS.

Mol Cell Biol. 2003 May;23(9):3103-15.


Temporal production of the signaling lipid phosphatidic acid by phospholipase D2 determines the output of extracellular signal-regulated kinase signaling in cancer cells.

Zhang F, Wang Z, Lu M, Yonekubo Y, Liang X, Zhang Y, Wu P, Zhou Y, Grinstein S, Hancock JF, Du G.

Mol Cell Biol. 2014 Jan;34(1):84-95. doi: 10.1128/MCB.00987-13. Epub 2013 Oct 28.

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