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Items: 1 to 20 of 77

1.

12/15-Lipoxygenase targets neuronal mitochondria under oxidative stress.

Pallast S, Arai K, Wang X, Lo EH, van Leyen K.

J Neurochem. 2009 Nov;111(3):882-9. doi: 10.1111/j.1471-4159.2009.06379.x. Epub 2009 Sep 8.

2.

The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis.

Liu Y, Wang W, Li Y, Xiao Y, Cheng J, Jia J.

Biol Pharm Bull. 2015;38(8):1234-9. doi: 10.1248/bpb.b15-00048.

3.

Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress.

Pfeiffer A, Jaeckel M, Lewerenz J, Noack R, Pouya A, Schacht T, Hoffmann C, Winter J, Schweiger S, Schäfer MK, Methner A.

Br J Pharmacol. 2014 Apr;171(8):2147-58. doi: 10.1111/bph.12549.

4.

Lamotrigine inhibition of rotenone- or 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death.

Kim YJ, Ko HH, Han ES, Lee CS.

Brain Res Bull. 2007 Mar 30;71(6):633-40. Epub 2007 Jan 8.

PMID:
17292807
5.

Activation of large-conductance Ca(2+)-activated K(+) channels inhibits glutamate-induced oxidative stress through attenuating ER stress and mitochondrial dysfunction.

Yan XH, Guo XY, Jiao FY, Liu X, Liu Y.

Neurochem Int. 2015 Nov;90:28-35. doi: 10.1016/j.neuint.2015.07.004. Epub 2015 Jul 7.

PMID:
26163046
6.

Persistent mitochondrial dysfunction and oxidative stress hinder neuronal cell recovery from reversible proteasome inhibition.

Papa L, Rockwell P.

Apoptosis. 2008 Apr;13(4):588-99. doi: 10.1007/s10495-008-0182-0.

PMID:
18299995
7.

Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons.

Tobaben S, Grohm J, Seiler A, Conrad M, Plesnila N, Culmsee C.

Cell Death Differ. 2011 Feb;18(2):282-92. doi: 10.1038/cdd.2010.92. Epub 2010 Aug 6.

8.

Genetic ablation and short-duration inhibition of lipoxygenase results in increased macroautophagy.

Jang I, Park S, Cho JW, Yigitkanli K, van Leyen K, Roth J.

Exp Cell Res. 2014 Feb 15;321(2):276-87. doi: 10.1016/j.yexcr.2013.11.017. Epub 2013 Nov 26.

PMID:
24291223
9.

Alginate oligosaccharide protects against endoplasmic reticulum- and mitochondrial-mediated apoptotic cell death and oxidative stress.

Tusi SK, Khalaj L, Ashabi G, Kiaei M, Khodagholi F.

Biomaterials. 2011 Aug;32(23):5438-58. doi: 10.1016/j.biomaterials.2011.04.024. Epub 2011 May 2.

PMID:
21543116
12.

Prevention of 7-ketocholesterol-induced mitochondrial damage and cell death by calmodulin inhibition.

Han JH, Kim YJ, Han ES, Lee CS.

Brain Res. 2007 Mar 16;1137(1):11-9. Epub 2006 Dec 20.

PMID:
17224136
13.

Protective efficacy of mitochondrial targeted antioxidant MitoQ against dichlorvos induced oxidative stress and cell death in rat brain.

Wani WY, Gudup S, Sunkaria A, Bal A, Singh PP, Kandimalla RJ, Sharma DR, Gill KD.

Neuropharmacology. 2011 Dec;61(8):1193-201. doi: 10.1016/j.neuropharm.2011.07.008. Epub 2011 Jul 26.

PMID:
21784090
15.

Novel lipoxygenase inhibitors as neuroprotective reagents.

van Leyen K, Arai K, Jin G, Kenyon V, Gerstner B, Rosenberg PA, Holman TR, Lo EH.

J Neurosci Res. 2008 Mar;86(4):904-9.

16.

Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia.

Jin G, Arai K, Murata Y, Wang S, Stins MF, Lo EH, van Leyen K.

Stroke. 2008 Sep;39(9):2538-43. doi: 10.1161/STROKEAHA.108.514927. Epub 2008 Jul 17.

17.

STAT-dependent upregulation of 12/15-lipoxygenase contributes to neuronal injury after stroke.

Jung JE, Karatas H, Liu Y, Yalcin A, Montaner J, Lo EH, van Leyen K.

J Cereb Blood Flow Metab. 2015 Dec;35(12):2043-51. doi: 10.1038/jcbfm.2015.169. Epub 2015 Jul 15.

18.

Oxidative neuronal death caused by glutamate uptake inhibition in cultured hippocampal neurons.

Himi T, Ikeda M, Yasuhara T, Murota SI.

J Neurosci Res. 2003 Mar 1;71(5):679-88.

PMID:
12584726
19.

JM-20, a novel benzodiazepine–dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro.

Nuñez-Figueredo Y, Ramírez-Sánchez J, Delgado-Hernández R, Porto-Verdecia M, Ochoa-Rodríguez E, Verdecia-Reyes Y, Marin-Prida J, González-Durruthy M, Uyemura SA, Rodrigues FP, Curti C, Souza DO, Pardo-Andreu GL.

Eur J Pharmacol. 2014 Mar 5;726:57-65.

20.

Exendin-4 protects mitochondria from reactive oxygen species induced apoptosis in pancreatic Beta cells.

Li Z, Zhou Z, Huang G, Hu F, Xiang Y, He L.

PLoS One. 2013 Oct 24;8(10):e76172. doi: 10.1371/journal.pone.0076172. eCollection 2013 Oct 24.

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