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Items: 1 to 20 of 158


Myotendinous junction defects and reduced force transmission in mice that lack alpha7 integrin and utrophin.

Welser JV, Rooney JE, Cohen NC, Gurpur PB, Singer CA, Evans RA, Haines BA, Burkin DJ.

Am J Pathol. 2009 Oct;175(4):1545-54. doi: 10.2353/ajpath.2009.090052. Epub 2009 Sep 3.


Sarcospan integration into laminin-binding adhesion complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin.

Marshall JL, Oh J, Chou E, Lee JA, Holmberg J, Burkin DJ, Crosbie-Watson RH.

Hum Mol Genet. 2015 Apr 1;24(7):2011-22. doi: 10.1093/hmg/ddu615. Epub 2014 Dec 11.


Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin.

Rooney JE, Welser JV, Dechert MA, Flintoff-Dye NL, Kaufman SJ, Burkin DJ.

J Cell Sci. 2006 Jun 1;119(Pt 11):2185-95. Epub 2006 May 9.


Dystrophin and utrophin expression require sarcospan: loss of α7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice.

Marshall JL, Chou E, Oh J, Kwok A, Burkin DJ, Crosbie-Watson RH.

Hum Mol Genet. 2012 Oct 15;21(20):4378-93. Epub 2012 Jul 13.


Absence of alpha 7 integrin in dystrophin-deficient mice causes a myopathy similar to Duchenne muscular dystrophy.

Guo C, Willem M, Werner A, Raivich G, Emerson M, Neyses L, Mayer U.

Hum Mol Genet. 2006 Mar 15;15(6):989-98. Epub 2006 Feb 13.


Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.

Burkin DJ, Wallace GQ, Nicol KJ, Kaufman DJ, Kaufman SJ.

J Cell Biol. 2001 Mar 19;152(6):1207-18.


Alpha 7 integrin preserves the function of the extensor digitorum longus muscle in dystrophin-null mice.

Hakim CH, Burkin DJ, Duan D.

J Appl Physiol (1985). 2013 Nov 1;115(9):1388-92. doi: 10.1152/japplphysiol.00602.2013. Epub 2013 Aug 29.


Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx mice.

Li D, Long C, Yue Y, Duan D.

Hum Mol Genet. 2009 Apr 1;18(7):1209-20. doi: 10.1093/hmg/ddp015. Epub 2009 Jan 8.


Sarcospan: a small protein with large potential for Duchenne muscular dystrophy.

Marshall JL, Crosbie-Watson RH.

Skelet Muscle. 2013 Jan 3;3(1):1. doi: 10.1186/2044-5040-3-1.


Secondary reduction of alpha7B integrin in laminin alpha2 deficient congenital muscular dystrophy supports an additional transmembrane link in skeletal muscle.

Cohn RD, Mayer U, Saher G, Herrmann R, van der Flier A, Sonnenberg A, Sorokin L, Voit T.

J Neurol Sci. 1999 Mar 1;163(2):140-52.


Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy.

Wuebbles RD, Sarathy A, Kornegay JN, Burkin DJ.

Dis Model Mech. 2013 Sep;6(5):1175-84. doi: 10.1242/dmm.012211. Epub 2013 Jul 11.


Organization of the myotendinous junction is dependent on the presence of alpha7beta1 integrin.

Miosge N, Klenczar C, Herken R, Willem M, Mayer U.

Lab Invest. 1999 Dec;79(12):1591-9.


β1D chain increases α7β1 integrin and laminin and protects against sarcolemmal damage in mdx mice.

Liu J, Milner DJ, Boppart MD, Ross RS, Kaufman SJ.

Hum Mol Genet. 2012 Apr 1;21(7):1592-603. doi: 10.1093/hmg/ddr596. Epub 2011 Dec 16.


Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A.

Doe JA, Wuebbles RD, Allred ET, Rooney JE, Elorza M, Burkin DJ.

J Cell Sci. 2011 Jul 1;124(Pt 13):2287-97. doi: 10.1242/jcs.083311. Epub 2011 Jun 7.


Utrophin-dystrophin-deficient mice as a model for Duchenne muscular dystrophy.

Deconinck AE, Rafael JA, Skinner JA, Brown SC, Potter AC, Metzinger L, Watt DJ, Dickson JG, Tinsley JM, Davies KE.

Cell. 1997 Aug 22;90(4):717-27.


Human α7 Integrin Gene (ITGA7) Delivered by Adeno-Associated Virus Extends Survival of Severely Affected Dystrophin/Utrophin-Deficient Mice.

Heller KN, Montgomery CL, Shontz KM, Clark KR, Mendell JR, Rodino-Klapac LR.

Hum Gene Ther. 2015 Oct;26(10):647-56. doi: 10.1089/hum.2015.062. Epub 2015 Aug 11.


Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.

van Putten M, Kumar D, Hulsker M, Hoogaars WM, Plomp JJ, van Opstal A, van Iterson M, Admiraal P, van Ommen GJ, 't Hoen PA, Aartsma-Rus A.

Neuromuscul Disord. 2012 May;22(5):406-17. doi: 10.1016/j.nmd.2011.10.011. Epub 2012 Jan 27.

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