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Items: 1 to 20 of 71

1.

In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines.

Behrsing HP, Furniss MJ, Robillard KA, Tomaszewski JE, Parchment RE.

Cancer Chemother Pharmacol. 2010 May;65(6):1083-91. doi: 10.1007/s00280-009-1113-7. Epub 2009 Aug 29.

PMID:
19727731
2.

2-amino-O4-benzylpteridine derivatives: potent inactivators of O6-alkylguanine-DNA alkyltransferase.

Nelson ME, Loktionova NA, Pegg AE, Moschel RC.

J Med Chem. 2004 Jul 15;47(15):3887-91.

PMID:
15239666
3.

Modulation of nitrosourea resistance in myeloid leukemias.

Gerson SL, Trey JE.

Blood. 1988 May;71(5):1487-94.

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Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.

Hansen RJ, Nagasubramanian R, Delaney SM, Cherian MM, Lin S, Kogan SC, Dolan ME.

J Pharmacol Exp Ther. 2005 Dec;315(3):1247-55. Epub 2005 Aug 26.

9.

Inhibition of O6-alkylguanine-DNA alkyltransferase by O6-benzyl-N2-acetylguanosine increases chloroethylnitrosourea-induced apoptosis in Mer+ human melanoma cells.

Debiton E, Glasser AL, Marchenay C, Rolhion C, Maurizis JC, Madelmont JC.

Melanoma Res. 2002 Oct;12(5):417-27.

PMID:
12394182
10.

Evidence for nucleotide excision repair as a modifying factor of O6-methylguanine-DNA methyltransferase-mediated innate chloroethylnitrosourea resistance in human tumor cell lines.

Chen ZP, Malapetsa A, McQuillan A, Marcantonio D, Bello V, Mohr G, Remack J, Brent TP, Panasci LC.

Mol Pharmacol. 1997 Nov;52(5):815-20.

11.

Myelotoxic effects of the bifunctional alkylating agent bizelesin on human, canine and murine myeloid progenitor cells.

Volpe DA, Tomaszewski JE, Parchment RE, Garg A, Flora KP, Murphy MJ, Grieshaber CK.

Cancer Chemother Pharmacol. 1996;39(1-2):143-9.

PMID:
8995512
12.

Transcriptional repression of O6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N'-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells.

Ma LC, Kuo CC, Liu JF, Chen LT, Chang JY.

Mol Pharmacol. 2008 Aug;74(2):517-26. doi: 10.1124/mol.107.043620. Epub 2008 May 20.

15.

Bone marrow CFU-GM and human tumor xenograft efficacy of three antitumor nucleoside analogs.

Bagley RG, Roth S, Kurtzberg LS, Rouleau C, Yao M, Crawford J, Krumbholz R, Lovett D, Schmid S, Teicher BA.

Int J Oncol. 2009 May;34(5):1329-40.

PMID:
19360345
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O6-Benzylguanine potentiates BCNU but not busulfan toxicity in hematopoietic stem cells.

Westerhof GR, Down JD, Blokland I, Wood M, Boudewijn A, Watson AJ, McGown AT, Ploemacher RE, Margison GP.

Exp Hematol. 2001 May;29(5):633-8.

PMID:
11376877
20.

TGF-beta 3 protects normal human hematopoietic progenitor cells treated with 4-hydroperoxycyclophosphamide in vitro.

Lemoli RM, Strife A, Clarkson BD, Haley JD, Gulati SC.

Exp Hematol. 1992 Dec;20(11):1252-6.

PMID:
1493854

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