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Items: 1 to 20 of 135

1.

Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c/g polymorphism.

Roussos P, Giakoumaki SG, Bitsios P.

Biol Psychiatry. 2009 Dec 1;66(11):997-1004. doi: 10.1016/j.biopsych.2009.07.008. Epub 2009 Aug 22.

PMID:
19699472
2.

Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism.

Giakoumaki SG, Roussos P, Bitsios P.

Neuropsychopharmacology. 2008 Dec;33(13):3058-68. doi: 10.1038/npp.2008.82. Epub 2008 Jun 4.

3.

Effects of tolcapone on working memory and brain activity in abstinent smokers: a proof-of-concept study.

Ashare RL, Wileyto EP, Ruparel K, Goelz PM, Hopson RD, Valdez JN, Gur RC, Loughead J, Lerman C.

Drug Alcohol Depend. 2013 Dec 15;133(3):852-6. doi: 10.1016/j.drugalcdep.2013.09.003. Epub 2013 Sep 14.

4.

Tolcapone enhances food-evoked dopamine efflux and executive memory processes mediated by the rat prefrontal cortex.

Lapish CC, Ahn S, Evangelista LM, So K, Seamans JK, Phillips AG.

Psychopharmacology (Berl). 2009 Jan;202(1-3):521-30. doi: 10.1007/s00213-008-1342-1. Epub 2008 Oct 15.

PMID:
18854987
5.

COMT Val(158)Met genotype determines the direction of cognitive effects produced by catechol-O-methyltransferase inhibition.

Farrell SM, Tunbridge EM, Braeutigam S, Harrison PJ.

Biol Psychiatry. 2012 Mar 15;71(6):538-44. doi: 10.1016/j.biopsych.2011.12.023. Erratum in: Biol Psychiatry. 2015 Feb 1;77(3):304.

6.

Tolcapone improves cognition and cortical information processing in normal human subjects.

Apud JA, Mattay V, Chen J, Kolachana BS, Callicott JH, Rasetti R, Alce G, Iudicello JE, Akbar N, Egan MF, Goldberg TE, Weinberger DR.

Neuropsychopharmacology. 2007 May;32(5):1011-20. Epub 2006 Oct 25.

7.

Catechol O-methyltransferase inhibitor tolcapone has minor influence on performance in experimental memory models in rats.

Liljequist R, Haapalinna A, Ahlander M, Li YH, Männistö PT.

Behav Brain Res. 1997 Jan;82(2):195-202.

PMID:
9030401
8.

Prepulse inhibition of the startle reflex depends on the catechol O-methyltransferase Val158Met gene polymorphism.

Roussos P, Giakoumaki SG, Rogdaki M, Pavlakis S, Frangou S, Bitsios P.

Psychol Med. 2008 Nov;38(11):1651-8. doi: 10.1017/S0033291708002912. Epub 2008 Feb 8.

PMID:
18261249
9.

Opposite effects of tolcapone on amphetamine-disrupted startle gating in low vs. high COMT-expressing rat strains.

Swerdlow NR, Hines SR, Herrera SD, Weber M, Breier MR.

Pharmacol Biochem Behav. 2013 May;106:128-31. doi: 10.1016/j.pbb.2013.03.015. Epub 2013 Apr 6.

10.

Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia.

Goldberg TE, Egan MF, Gscheidle T, Coppola R, Weickert T, Kolachana BS, Goldman D, Weinberger DR.

Arch Gen Psychiatry. 2003 Sep;60(9):889-96.

PMID:
12963670
11.

A proof of concept study of tolcapone for pathological gambling: relationships with COMT genotype and brain activation.

Grant JE, Odlaug BL, Chamberlain SR, Hampshire A, Schreiber LR, Kim SW.

Eur Neuropsychopharmacol. 2013 Nov;23(11):1587-96. doi: 10.1016/j.euroneuro.2013.07.008. Epub 2013 Aug 6.

PMID:
23953269
12.

The COMT Val158Met polymorphism modulates working memory performance under acute stress.

Buckert M, Kudielka BM, Reuter M, Fiebach CJ.

Psychoneuroendocrinology. 2012 Nov;37(11):1810-21. doi: 10.1016/j.psyneuen.2012.03.014. Epub 2012 Apr 14.

PMID:
22503421
13.

Effects of peripheral and central catechol-O-methyltransferase inhibition on striatal extracellular levels of dopamine: a microdialysis study in freely moving rats.

Napolitano A, Bellini G, Borroni E, Zürcher G, Bonuccelli U.

Parkinsonism Relat Disord. 2003 Jan;9(3):145-50.

PMID:
12573869
14.
15.

Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: a replication study.

Quednow BB, Schmechtig A, Ettinger U, Petrovsky N, Collier DA, Vollenweider FX, Wagner M, Kumari V.

Biol Psychiatry. 2009 Sep 15;66(6):614-20. doi: 10.1016/j.biopsych.2009.05.007. Epub 2009 Jun 28.

16.

Effect of tolcapone on brain activity during a variable attentional control task: a double-blind, placebo-controlled, counter-balanced trial in healthy volunteers.

Magalona SC, Rasetti R, Chen J, Chen Q, Gold I, Decot H, Callicott JH, Berman KF, Apud JA, Weinberger DR, Mattay VS.

CNS Drugs. 2013 Aug;27(8):663-73. doi: 10.1007/s40263-013-0082-x.

17.
18.

The effect of COMT inhibition by tolcapone on tolerability and pharmacokinetics of different levodopa/benserazide formulations.

Jorga K, Fotteler B, Schmitt M, Nielsen T, Zürcher G, Aitken J.

Eur Neurol. 1997;38(1):59-67.

PMID:
9252801
19.

Effects of tolcapone upon soluble and membrane-bound brain and liver catechol-O-methyltransferase.

Vieira-Coelho MA, Soares-da-Silva P.

Brain Res. 1999 Mar 6;821(1):69-78.

PMID:
10064789
20.

Tolcapone improves motor function in parkinsonian patients with the "wearing-off" phenomenon: a double-blind, placebo-controlled, multicenter trial.

Rajput AH, Martin W, Saint-Hilaire MH, Dorflinger E, Pedder S.

Neurology. 1998 May;50(5 Suppl 5):S54-9.

PMID:
9591523

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