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Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation.

Xie YB, Park JH, Kim DK, Hwang JH, Oh S, Park SB, Shong M, Lee IK, Choi HS.

J Biol Chem. 2009 Oct 16;284(42):28762-74. doi: 10.1074/jbc.M109.034165. Epub 2009 Aug 18.


Molecular characterization of SMILE as a novel corepressor of nuclear receptors.

Xie YB, Nedumaran B, Choi HS.

Nucleic Acids Res. 2009 Jul;37(12):4100-15. doi: 10.1093/nar/gkp333. Epub 2009 May 8.


Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is key regulator of hepatic gluconeogenesis.

Kim DK, Ryu D, Koh M, Lee MW, Lim D, Kim MJ, Kim YH, Cho WJ, Lee CH, Park SB, Koo SH, Choi HS.

J Biol Chem. 2012 Jun 22;287(26):21628-39. doi: 10.1074/jbc.M111.315168. Epub 2012 May 1.


SMILE, a new orphan nuclear receptor SHP-interacting protein, regulates SHP-repressed estrogen receptor transactivation.

Xie YB, Lee OH, Nedumaran B, Seong HA, Lee KM, Ha H, Lee IK, Yun Y, Choi HS.

Biochem J. 2008 Dec 15;416(3):463-73. doi: 10.1042/BJ20080782.


Transcriptional cross talk between orphan nuclear receptor ERRγ and transmembrane transcription factor ATF6α coordinates endoplasmic reticulum stress response.

Misra J, Kim DK, Choi W, Koo SH, Lee CH, Back SH, Kaufman RJ, Choi HS.

Nucleic Acids Res. 2013 Aug;41(14):6960-74. doi: 10.1093/nar/gkt429. Epub 2013 May 28.


Inverse Agonist of Estrogen-Related Receptor γ Enhances Sodium Iodide Symporter Function Through Mitogen-Activated Protein Kinase Signaling in Anaplastic Thyroid Cancer Cells.

Singh TD, Jeong SY, Lee SW, Ha JH, Lee IK, Kim SH, Kim J, Cho SJ, Ahn BC, Lee J, Jeon YH.

J Nucl Med. 2015 Nov;56(11):1690-6. doi: 10.2967/jnumed.115.160366. Epub 2015 Sep 3.


An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRgamma.

Park YY, Ahn SW, Kim HJ, Kim JM, Lee IK, Kang H, Choi HS.

Nucleic Acids Res. 2005 Nov 28;33(21):6756-68. Print 2005.


Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation.

Chanda D, Xie YB, Choi HS.

Nucleic Acids Res. 2010 Aug;38(14):4607-19. doi: 10.1093/nar/gkq227. Epub 2010 Apr 7.


Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis.

Aquilano K, Vigilanza P, Baldelli S, Pagliei B, Rotilio G, Ciriolo MR.

J Biol Chem. 2010 Jul 9;285(28):21590-9. doi: 10.1074/jbc.M109.070169. Epub 2010 May 6.


SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD.

Amat R, Planavila A, Chen SL, Iglesias R, Giralt M, Villarroya F.

J Biol Chem. 2009 Aug 14;284(33):21872-80. doi: 10.1074/jbc.M109.022749. Epub 2009 Jun 24.


Structural activity relationship of flavonoids with estrogen-related receptor gamma.

Huang Z, Fang F, Wang J, Wong CW.

FEBS Lett. 2010 Jan 4;584(1):22-6. doi: 10.1016/j.febslet.2009.11.026.


Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis.

Lee JM, Seo WY, Han HS, Oh KJ, Lee YS, Kim DK, Choi S, Choi BH, Harris RA, Lee CH, Koo SH, Choi HS.

Diabetes. 2016 Jan;65(1):62-73. doi: 10.2337/db15-0249. Epub 2015 Sep 4.


Requirements for transcriptional regulation by the orphan nuclear receptor ERRgamma.

Huppunen J, Wohlfahrt G, Aarnisalo P.

Mol Cell Endocrinol. 2004 Apr 30;219(1-2):151-60.


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