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Items: 1 to 20 of 109

1.

Discoidin domain receptor 2 (DDR2) is required for maintenance of spermatogenesis in male mice.

Kano K, Kitamura A, Matsuwaki T, Morimatsu M, Naito K.

Mol Reprod Dev. 2010 Jan;77(1):29-37. doi: 10.1002/mrd.21093.

PMID:
19681157
2.

Transcriptome analysis reveals an unexpected role of a collagen tyrosine kinase receptor gene, Ddr2, as a regulator of ovarian function.

Matsumura H, Kano K, Marín de Evsikova C, Young JA, Nishina PM, Naggert JK, Naito K.

Physiol Genomics. 2009 Oct 7;39(2):120-9. doi: 10.1152/physiolgenomics.00073.2009. Epub 2009 Aug 11.

3.

Abnormal Accumulation of Collagen Type I Due to the Loss of Discoidin Domain Receptor 2 (Ddr2) Promotes Testicular Interstitial Dysfunction.

Zhu CC, Tang B, Su J, Zhao H, Bu X, Li Z, Zhao J, Gong WD, Wu ZQ, Yao LB, Li W, Zhang YQ.

PLoS One. 2015 Jul 9;10(7):e0131947. doi: 10.1371/journal.pone.0131947. eCollection 2015.

4.

A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse.

Kano K, Marín de Evsikova C, Young J, Wnek C, Maddatu TP, Nishina PM, Naggert JK.

Mol Endocrinol. 2008 Aug;22(8):1866-80. doi: 10.1210/me.2007-0310. Epub 2008 May 15.

5.

Discoidin Receptor 2 Controls Bone Formation and Marrow Adipogenesis.

Ge C, Wang Z, Zhao G, Li B, Liao J, Sun H, Franceschi RT.

J Bone Miner Res. 2016 Dec;31(12):2193-2203. doi: 10.1002/jbmr.2893. Epub 2016 Oct 31.

6.

An essential role of discoidin domain receptor 2 (DDR2) in osteoblast differentiation and chondrocyte maturation via modulation of Runx2 activation.

Zhang Y, Su J, Yu J, Bu X, Ren T, Liu X, Yao L.

J Bone Miner Res. 2011 Mar;26(3):604-17. doi: 10.1002/jbmr.225.

7.

Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging.

Ge C, Mohamed F, Binrayes A, Kapila S, Franceschi RT.

J Dent Res. 2017 Oct 1:22034517738190. doi: 10.1177/0022034517738190. [Epub ahead of print]

PMID:
29073363
8.

The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism.

Labrador JP, Azcoitia V, Tuckermann J, Lin C, Olaso E, Mañes S, Brückner K, Goergen JL, Lemke G, Yancopoulos G, Angel P, Martínez C, Klein R.

EMBO Rep. 2001 May;2(5):446-52.

9.

Discoidin domain receptor 2 facilitates prostate cancer bone metastasis via regulating parathyroid hormone-related protein.

Yan Z, Jin S, Wei Z, Huilian H, Zhanhai Y, Yue T, Juan L, Jing L, Libo Y, Xu L.

Biochim Biophys Acta. 2014 Sep;1842(9):1350-63. doi: 10.1016/j.bbadis.2014.04.018. Epub 2014 Apr 27.

10.

Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants.

Iwai LK, Payne LS, Luczynski MT, Chang F, Xu H, Clinton RW, Paul A, Esposito EA, Gridley S, Leitinger B, Naegle KM, Huang PH.

Biochem J. 2013 Sep 15;454(3):501-13. doi: 10.1042/BJ20121750.

11.

Tyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formation.

Yang K, Kim JH, Kim HJ, Park IS, Kim IY, Yang BS.

J Biol Chem. 2005 Nov 25;280(47):39058-66. Epub 2005 Sep 26.

12.

The anti-angiogenic role of discoidin domain receptor 2 (DDR2) in laser-induced choroidal neovascularization.

Zhu T, Zhu J, Bu X, Zhao H, Zhang S, Chang Y, Li R, Yao L, Wang Y, Su J.

J Mol Med (Berl). 2015 Feb;93(2):187-98. doi: 10.1007/s00109-014-1213-7. Epub 2014 Oct 30.

PMID:
25355563
13.

Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2.

Olaso E, Labrador JP, Wang L, Ikeda K, Eng FJ, Klein R, Lovett DH, Lin HC, Friedman SL.

J Biol Chem. 2002 Feb 1;277(5):3606-13. Epub 2001 Nov 26.

14.

Downregulation of discoidin domain receptor 2 in A375 human melanoma cells reduces its experimental liver metastasis ability.

Badiola I, Villacé P, Basaldua I, Olaso E.

Oncol Rep. 2011 Oct;26(4):971-8. doi: 10.3892/or.2011.1356. Epub 2011 Jun 23.

PMID:
21701781
15.

DDR2 (discoidin domain receptor 2) suppresses osteoclastogenesis and is a potential therapeutic target in osteoporosis.

Zhang Y, Su J, Wu S, Teng Y, Yin Z, Guo Y, Li J, Li K, Yao L, Li X.

Sci Signal. 2015 Mar 24;8(369):ra31. doi: 10.1126/scisignal.2005835.

PMID:
25805889
17.

The intracellular juxtamembrane domain of discoidin domain receptor 2 (DDR2) is essential for receptor activation and DDR2-mediated cancer progression.

Kim D, Ko P, You E, Rhee S.

Int J Cancer. 2014 Dec 1;135(11):2547-57. doi: 10.1002/ijc.28901. Epub 2014 Apr 22.

18.

Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients.

Ali BR, Xu H, Akawi NA, John A, Karuvantevida NS, Langer R, Al-Gazali L, Leitinger B.

Hum Mol Genet. 2010 Jun 1;19(11):2239-50. doi: 10.1093/hmg/ddq103. Epub 2010 Mar 10.

19.

Discoidin domain receptor 2 is involved in the activation of bone marrow-derived dendritic cells caused by type I collagen.

Lee JE, Kang CS, Guan XY, Kim BT, Kim SH, Lee YM, Moon WS, Kim DK.

Biochem Biophys Res Commun. 2007 Jan 5;352(1):244-50. Epub 2006 Nov 13.

PMID:
17113033
20.

[The attachment manner of ubiquitin to proinflammatory molecule discoidin domain receptor 2].

Yu J, Bu X, Zhao H, Li X, Su J.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2015 Aug;31(8):1077-80. Chinese.

PMID:
26271983

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