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Items: 1 to 20 of 117

1.

Inhibitors of RecA activity discovered by high-throughput screening: cell-permeable small molecules attenuate the SOS response in Escherichia coli.

Wigle TJ, Sexton JZ, Gromova AV, Hadimani MB, Hughes MA, Smith GR, Yeh LA, Singleton SF.

J Biomol Screen. 2009 Oct;14(9):1092-101. doi: 10.1177/1087057109342126. Epub 2009 Aug 12.

2.

Suramin is a potent and selective inhibitor of Mycobacterium tuberculosis RecA protein and the SOS response: RecA as a potential target for antibacterial drug discovery.

Nautiyal A, Patil KN, Muniyappa K.

J Antimicrob Chemother. 2014 Jul;69(7):1834-43. doi: 10.1093/jac/dku080. Epub 2014 Apr 9.

PMID:
24722837
3.

RecA-mediated SOS response provides a geraniol tolerance in Escherichia coli.

Shah AA, Wang C, Yoon SH, Kim JY, Choi ES, Kim SW.

J Biotechnol. 2013 Sep 20;167(4):357-64. doi: 10.1016/j.jbiotec.2013.07.023. Epub 2013 Jul 29.

PMID:
23906844
4.

A novel high-throughput cell-based assay aimed at identifying inhibitors of DNA metabolism in bacteria.

Fan J, de Jonge BL, MacCormack K, Sriram S, McLaughlin RE, Plant H, Preston M, Fleming PR, Albert R, Foulk M, Mills SD.

Antimicrob Agents Chemother. 2014 Dec;58(12):7264-72. doi: 10.1128/AAC.03475-14. Epub 2014 Sep 22.

5.

A complementary pair of rapid molecular screening assays for RecA activities.

Lee AM, Wigle TJ, Singleton SF.

Anal Biochem. 2007 Aug 15;367(2):247-58. Epub 2007 Apr 20.

6.

Overexpression of SOS genes in ciprofloxacin resistant Escherichia coli mutants.

Pourahmad Jaktaji R, Pasand S.

Gene. 2016 Jan 15;576(1 Pt 1):115-8. doi: 10.1016/j.gene.2015.09.069. Epub 2015 Oct 2.

PMID:
26432001
7.
8.

Knockdown of recA gene expression by artificial small RNAs in Escherichia coli.

Sharma V, Sakai Y, Smythe KA, Yokobayashi Y.

Biochem Biophys Res Commun. 2013 Jan 4;430(1):256-9. doi: 10.1016/j.bbrc.2012.10.141. Epub 2012 Nov 20.

PMID:
23178465
9.

Baicalein suppresses the SOS response system of Staphylococcus aureus induced by ciprofloxacin.

Peng Q, Zhou S, Yao F, Hou B, Huang Y, Hua D, Zheng Y, Qian Y.

Cell Physiol Biochem. 2011;28(5):1045-50. doi: 10.1159/000335791. Epub 2011 Dec 15.

10.

RecJ nuclease is required for SOS induction after introduction of a double-strand break in a RecA loading deficient recB mutant of Escherichia coli.

Vlasić I, Ivancić-Baće I, Imesek M, Mihaljević B, Brcić-Kostić K.

Biochimie. 2008 Sep;90(9):1347-55. doi: 10.1016/j.biochi.2008.04.002. Epub 2008 Apr 10.

PMID:
18445487
11.

Effects of Stress, Reactive Oxygen Species, and the SOS Response on De Novo Acquisition of Antibiotic Resistance in Escherichia coli.

Händel N, Hoeksema M, Freijo Mata M, Brul S, ter Kuile BH.

Antimicrob Agents Chemother. 2015 Dec 14;60(3):1319-27. doi: 10.1128/AAC.02684-15.

12.

The expression of Escherichia coli SOS genes recA and uvrA is inducible by polyamines.

Oh TJ, Kim IG.

Biochem Biophys Res Commun. 1999 Oct 22;264(2):584-9.

PMID:
10529406
14.

Genetic evidence for the requirement of RecA loading activity in SOS induction after UV irradiation in Escherichia coli.

Ivancic-Bace I, Vlasic I, Salaj-Smic E, Brcic-Kostic K.

J Bacteriol. 2006 Jul;188(14):5024-32.

15.

Two modes of binding of DinI to RecA filament provide a new insight into the regulation of SOS response by DinI protein.

Galkin VE, Britt RL, Bane LB, Yu X, Cox MM, Egelman EH.

J Mol Biol. 2011 May 20;408(5):815-24. doi: 10.1016/j.jmb.2011.03.046. Epub 2011 Mar 31.

16.

Directed molecular screening for RecA ATPase inhibitors.

Wigle TJ, Singleton SF.

Bioorg Med Chem Lett. 2007 Jun 15;17(12):3249-53. Epub 2007 Apr 10.

17.

Role of RecA and the SOS response in thymineless death in Escherichia coli.

Fonville NC, Bates D, Hastings PJ, Hanawalt PC, Rosenberg SM.

PLoS Genet. 2010 Mar 5;6(3):e1000865. doi: 10.1371/journal.pgen.1000865.

18.

The Escherichia coli DinD protein modulates RecA activity by inhibiting postsynaptic RecA filaments.

Uranga LA, Balise VD, Benally CV, Grey A, Lusetti SL.

J Biol Chem. 2011 Aug 26;286(34):29480-91. doi: 10.1074/jbc.M111.245373. Epub 2011 Jun 22.

19.

Induction of the SOS response by hydroxyurea in Escherichia coli K12.

Barbé J, Villaverde A, Guerrero R.

Mutat Res. 1987 Oct;192(2):105-8.

PMID:
3309645
20.

RecA Inhibitors Potentiate Antibiotic Activity and Block Evolution of Antibiotic Resistance.

Alam MK, Alhhazmi A, DeCoteau JF, Luo Y, Geyer CR.

Cell Chem Biol. 2016 Mar 17;23(3):381-91. doi: 10.1016/j.chembiol.2016.02.010.

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