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Items: 1 to 20 of 98

1.

Metabolic glycoengineering: sialic acid and beyond.

Du J, Meledeo MA, Wang Z, Khanna HS, Paruchuri VD, Yarema KJ.

Glycobiology. 2009 Dec;19(12):1382-401. doi: 10.1093/glycob/cwp115. Epub 2009 Aug 12. Review.

2.

Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them.

Viswanathan K, Lawrence S, Hinderlich S, Yarema KJ, Lee YC, Betenbaugh MJ.

Biochemistry. 2003 Dec 30;42(51):15215-25.

PMID:
14690432
3.

Characterization of the metabolic flux and apoptotic effects of O-hydroxyl- and N-acyl-modified N-acetylmannosamine analogs in Jurkat cells.

Kim EJ, Sampathkumar SG, Jones MB, Rhee JK, Baskaran G, Goon S, Yarema KJ.

J Biol Chem. 2004 Apr 30;279(18):18342-52. Epub 2004 Feb 13.

4.

Metabolism of vertebrate amino sugars with N-glycolyl groups: incorporation of N-glycolylhexosamines into mammalian glycans by feeding N-glycolylgalactosamine.

Bergfeld AK, Pearce OM, Diaz SL, Lawrence R, Vocadlo DJ, Choudhury B, Esko JD, Varki A.

J Biol Chem. 2012 Aug 17;287(34):28898-916. doi: 10.1074/jbc.M112.363499. Epub 2012 Jun 12.

5.

Experimental Design Considerations for In Vitro Non-Natural Glycan Display via Metabolic Oligosaccharide Engineering.

Tan E, Almaraz RT, Khanna HS, Du J, Yarema KJ.

Curr Protoc Chem Biol. 2010 Sep 1;2(3):171-94. doi: 10.1002/9780470559277.ch100059.

6.

Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations.

Almaraz RT, Aich U, Khanna HS, Tan E, Bhattacharya R, Shah S, Yarema KJ.

Biotechnol Bioeng. 2012 Apr;109(4):992-1006. doi: 10.1002/bit.24363. Epub 2011 Nov 21.

7.

Metabolic glycoengineering through the mammalian GalNAc salvage pathway.

Pouilly S, Piller V, Piller F.

FEBS J. 2012 Feb;279(4):586-98. doi: 10.1111/j.1742-4658.2011.08448.x. Epub 2012 Jan 13.

8.

Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine.

Natunen S, Lampinen M, Suila H, Ritamo I, Pitkänen V, Nairn AV, Räbinä J, Laitinen S, Moremen KW, Reutter W, Valmu L.

Glycobiology. 2013 Aug;23(8):1004-12. doi: 10.1093/glycob/cwt039. Epub 2013 May 25.

9.

Selective exo-enzymatic labeling of N-glycans on the surface of living cells by recombinant ST6Gal I.

Mbua NE, Li X, Flanagan-Steet HR, Meng L, Aoki K, Moremen KW, Wolfert MA, Steet R, Boons GJ.

Angew Chem Int Ed Engl. 2013 Dec 2;52(49):13012-5. doi: 10.1002/anie.201307095. Epub 2013 Oct 15.

10.

Sialic Acid Glycoengineering Using an Unnatural Sialic Acid for the Detection of Sialoglycan Biosynthesis Defects and On-Cell Synthesis of Siglec Ligands.

Büll C, Heise T, Beurskens DM, Riemersma M, Ashikov A, Rutjes FP, van Kuppevelt TH, Lefeber DJ, den Brok MH, Adema GJ, Boltje TJ.

ACS Chem Biol. 2015 Oct 16;10(10):2353-63. doi: 10.1021/acschembio.5b00501. Epub 2015 Aug 10.

PMID:
26258433
11.

Engineering intracellular CMP-sialic acid metabolism into insect cells and methods to enhance its generation.

Viswanathan K, Narang S, Hinderlich S, Lee YC, Betenbaugh MJ.

Biochemistry. 2005 May 24;44(20):7526-34.

PMID:
15895995
12.

Substrate specificity of the sialic acid biosynthetic pathway.

Jacobs CL, Goon S, Yarema KJ, Hinderlich S, Hang HC, Chai DH, Bertozzi CR.

Biochemistry. 2001 Oct 30;40(43):12864-74.

PMID:
11669623
13.

Systemic blockade of sialylation in mice with a global inhibitor of sialyltransferases.

Macauley MS, Arlian BM, Rillahan CD, Pang PC, Bortell N, Marcondes MC, Haslam SM, Dell A, Paulson JC.

J Biol Chem. 2014 Dec 19;289(51):35149-58. doi: 10.1074/jbc.M114.606517. Epub 2014 Nov 3.

14.

Sialic acid metabolism and sialyltransferases: natural functions and applications.

Li Y, Chen X.

Appl Microbiol Biotechnol. 2012 May;94(4):887-905. doi: 10.1007/s00253-012-4040-1. Epub 2012 Apr 13. Review.

15.

Glycoengineering of Esterase Activity through Metabolic Flux-Based Modulation of Sialic Acid.

Mathew MP, Tan E, Labonte JW, Shah S, Saeui CT, Liu L, Bhattacharya R, Bovonratwet P, Gray JJ, Yarema KJ.

Chembiochem. 2017 Jul 4;18(13):1204-1215. doi: 10.1002/cbic.201600698. Epub 2017 Apr 20.

PMID:
28218815
16.

Importance of sialic acid residues illuminated by live animal imaging using phosphorylcholine self-assembled monolayer-coated quantum dots.

Ohyanagi T, Nagahori N, Shimawaki K, Hinou H, Yamashita T, Sasaki A, Jin T, Iwanaga T, Kinjo M, Nishimura S.

J Am Chem Soc. 2011 Aug 17;133(32):12507-17. doi: 10.1021/ja111201c. Epub 2011 Jul 25.

PMID:
21740000
17.

GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism.

Luchansky SJ, Yarema KJ, Takahashi S, Bertozzi CR.

J Biol Chem. 2003 Mar 7;278(10):8035-42. Epub 2002 Dec 23.

18.

Characterization of the cellular uptake and metabolic conversion of acetylated N-acetylmannosamine (ManNAc) analogues to sialic acids.

Jones MB, Teng H, Rhee JK, Lahar N, Baskaran G, Yarema KJ.

Biotechnol Bioeng. 2004 Feb 20;85(4):394-405.

PMID:
14755557
19.

Biochemical engineering of the N-acyl side chain of sialic acid: biological implications.

Keppler OT, Horstkorte R, Pawlita M, Schmidt C, Reutter W.

Glycobiology. 2001 Feb;11(2):11R-18R. Review.

PMID:
11287396
20.

Engineering Sialic Acid Synthesis Ability in Insect Cells.

Viswanathan K, Narang S, Betenbaugh MJ.

Methods Mol Biol. 2015;1321:171-8. doi: 10.1007/978-1-4939-2760-9_12.

PMID:
26082222

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