Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 124

1.

Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury.

Peng W, Cotrina ML, Han X, Yu H, Bekar L, Blum L, Takano T, Tian GF, Goldman SA, Nedergaard M.

Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12489-93. doi: 10.1073/pnas.0902531106. Epub 2009 Jul 27.

2.

A reassessment of P2X7 receptor inhibition as a neuroprotective strategy in rat models of contusion injury.

Marcillo A, Frydel B, Bramlett HM, Dietrich WD.

Exp Neurol. 2012 Feb;233(2):687-92. doi: 10.1016/j.expneurol.2011.06.008. Epub 2011 Nov 10.

3.

Localized inhibition of P2X7R at the spinal cord injury site improves neurogenic bladder dysfunction by decreasing urothelial P2X3R expression in rats.

Munoz A, Yazdi IK, Tang X, Rivera C, Taghipour N, Grossman RG, Boone TB, Tasciotti E.

Life Sci. 2017 Feb 15;171:60-67. doi: 10.1016/j.lfs.2016.12.017. Epub 2016 Dec 27.

PMID:
28039004
4.

P2X7 receptor inhibition improves recovery after spinal cord injury.

Wang X, Arcuino G, Takano T, Lin J, Peng WG, Wan P, Li P, Xu Q, Liu QS, Goldman SA, Nedergaard M.

Nat Med. 2004 Aug;10(8):821-7. Epub 2004 Jul 18.

PMID:
15258577
5.

P2X7 receptor inhibition increases CNTF in the subventricular zone, but not neurogenesis or neuroprotection after stroke in adult mice.

Kang SS, Keasey MP, Hagg T.

Transl Stroke Res. 2013 Oct;4(5):533-45. doi: 10.1007/s12975-013-0265-2.

6.

Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration.

Díaz-Hernández M, Díez-Zaera M, Sánchez-Nogueiro J, Gómez-Villafuertes R, Canals JM, Alberch J, Miras-Portugal MT, Lucas JJ.

FASEB J. 2009 Jun;23(6):1893-906. doi: 10.1096/fj.08-122275. Epub 2009 Jan 26.

PMID:
19171786
7.

Neuroprotective effects of brilliant blue G on the brain following traumatic brain injury in rats.

Wang YC, Cui Y, Cui JZ, Sun LQ, Cui CM, Zhang HA, Zhu HX, Li R, Tian YX, Gao JL.

Mol Med Rep. 2015 Aug;12(2):2149-54. doi: 10.3892/mmr.2015.3607. Epub 2015 Apr 14.

PMID:
25873133
8.

Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis.

Apolloni S, Amadio S, Parisi C, Matteucci A, Potenza RL, Armida M, Popoli P, D'Ambrosi N, Volonté C.

Dis Model Mech. 2014 Sep;7(9):1101-9. doi: 10.1242/dmm.017038. Epub 2014 Jul 18.

9.

Involvement of microglial P2X7 receptors and downstream signaling pathways in long-term potentiation of spinal nociceptive responses.

Chu YX, Zhang Y, Zhang YQ, Zhao ZQ.

Brain Behav Immun. 2010 Oct;24(7):1176-89. doi: 10.1016/j.bbi.2010.06.001. Epub 2010 Jun 8.

PMID:
20554014
10.

P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia.

Arbeloa J, Pérez-Samartín A, Gottlieb M, Matute C.

Neurobiol Dis. 2012 Mar;45(3):954-61. doi: 10.1016/j.nbd.2011.12.014. Epub 2011 Dec 11.

PMID:
22186422
11.

Block of purinergic P2X7R inhibits tumor growth in a C6 glioma brain tumor animal model.

Ryu JK, Jantaratnotai N, Serrano-Perez MC, McGeer PL, McLarnon JG.

J Neuropathol Exp Neurol. 2011 Jan;70(1):13-22. doi: 10.1097/NEN.0b013e318201d4d4.

PMID:
21157381
12.

Signaling pathways of ATP-induced PGE2 release in spinal cord astrocytes are EGFR transactivation-dependent.

Xia M, Zhu Y.

Glia. 2011 Apr;59(4):664-74. doi: 10.1002/glia.21138. Epub 2011 Feb 3.

PMID:
21294165
13.

Purinergic Receptors in Spinal Cord-Derived Ependymal Stem/Progenitor Cells and Their Potential Role in Cell-Based Therapy for Spinal Cord Injury.

Gómez-Villafuertes R, Rodríguez-Jiménez FJ, Alastrue-Agudo A, Stojkovic M, Miras-Portugal MT, Moreno-Manzano V.

Cell Transplant. 2015;24(8):1493-509. doi: 10.3727/096368914X682828. Epub 2014 Jul 15.

PMID:
25198194
14.

Neuroprotective Effects of Direct Intrathecal Administration of Granulocyte Colony-Stimulating Factor in Rats with Spinal Cord Injury.

Chen WF, Chen CH, Chen NF, Sung CS, Wen ZH.

CNS Neurosci Ther. 2015 Sep;21(9):698-707. doi: 10.1111/cns.12429. Epub 2015 Jul 20.

PMID:
26190345
15.

Involvement of spinal microglial P2X7 receptor in generation of tolerance to morphine analgesia in rats.

Zhou D, Chen ML, Zhang YQ, Zhao ZQ.

J Neurosci. 2010 Jun 9;30(23):8042-7. doi: 10.1523/JNEUROSCI.5377-09.2010.

16.

Ca(2+)-dependent reduction of glutamate aspartate transporter GLAST expression in astrocytes by P2X(7) receptor-mediated phosphoinositide 3-kinase signaling.

Liu YP, Yang CS, Chen MC, Sun SH, Tzeng SF.

J Neurochem. 2010 Apr;113(1):213-27. doi: 10.1111/j.1471-4159.2010.06589.x. Epub 2010 Jan 13.

17.

Microglial P2X₇ receptor in the hypothalamic paraventricular nuclei contributes to sympathoexcitatory responses in acute myocardial infarction rat.

Du D, Jiang M, Liu M, Wang J, Xia C, Guan R, Shen L, Ji Y, Zhu D.

Neurosci Lett. 2015 Feb 5;587:22-8. doi: 10.1016/j.neulet.2014.12.026. Epub 2014 Dec 15.

PMID:
25524407
18.

Inhibiting purinergic P2X7 receptors with the antagonist brilliant blue G is neuroprotective in an intranigral lipopolysaccharide animal model of Parkinson's disease.

Wang XH, Xie X, Luo XG, Shang H, He ZY.

Mol Med Rep. 2017 Feb;15(2):768-776. doi: 10.3892/mmr.2016.6070. Epub 2016 Dec 23.

19.

Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects.

Paterniti I, Melani A, Cipriani S, Corti F, Mello T, Mazzon E, Esposito E, Bramanti P, Cuzzocrea S, Pedata F.

J Neuroinflammation. 2011 Apr 12;8:31. doi: 10.1186/1742-2094-8-31.

20.

Minocycline treatment inhibits lipid peroxidation, preserves spinal cord ultrastructure, and improves functional outcome after traumatic spinal cord injury in the rat.

Sonmez E, Kabatas S, Ozen O, Karabay G, Turkoglu S, Ogus E, Yilmaz C, Caner H, Altinors N.

Spine (Phila Pa 1976). 2013 Jul 1;38(15):1253-9. doi: 10.1097/BRS.0b013e3182895587.

PMID:
23370685

Supplemental Content

Support Center