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Items: 1 to 20 of 889

1.

Solution behaviour and biomolecular interactions of two cytotoxic trans-platinum(II) complexes bearing aliphatic amine ligands.

Cubo L, Casini A, Gabbiani C, Mastrobuoni G, Messori L, Jiménez-Barbero J, Navarro-Ranninger C, Quiroga AG.

Chemistry. 2009 Sep 14;15(36):9139-46. doi: 10.1002/chem.200901090.

PMID:
19655350
2.

Influence of amine ligands on the aquation and cytotoxicity of trans-diamine platinum(II) anticancer complexes.

Cubo L, Quiroga AG, Zhang J, Thomas DS, Carnero A, Navarro-Ranninger C, Berners-Price SJ.

Dalton Trans. 2009 May 14;(18):3457-66. doi: 10.1039/b819301k. Epub 2009 Jan 29.

PMID:
19381408
3.

Inversion of the cis geometry requirement for cytotoxicity in structurally novel platinum(II) complexes containing the bidentate N,O-donor pyridin-2-yl-acetate.

Bierbach U, Sabat M, Farrell N.

Inorg Chem. 2000 May 1;39(9):1882-90. Erratum in: Inorg Chem 2000 Jun 26;39(13):2960.

PMID:
11428108
4.

Insights into the molecular mechanisms of protein platination from a case study: the reaction of anticancer platinum(II) iminoethers with horse heart cytochrome c.

Casini A, Gabbiani C, Mastrobuoni G, Pellicani RZ, Intini FP, Arnesano F, Natile G, Moneti G, Francese S, Messori L.

Biochemistry. 2007 Oct 30;46(43):12220-30. Epub 2007 Oct 9.

PMID:
17924668
5.

Platinum(II) complexes containing iminoethers: a trans platinum antitumour agent.

Coluccia M, Boccarelli A, Mariggiò MA, Cardellicchio N, Caputo P, Intini FP, Natile G.

Chem Biol Interact. 1995 Dec 22;98(3):251-66.

PMID:
8548863
6.

Novel apoptosis-inducing trans-platinum piperidine derivatives: synthesis and biological characterization.

Khazanov E, Barenholz Y, Gibson D, Najajreh Y.

J Med Chem. 2002 Nov 21;45(24):5196-204.

PMID:
12431047
7.

Design, synthesis, characterisation and chemical reactivity of mixed-ligand platinum(II) oxadiazoline complexes with potential cytotoxic properties.

Wagner G, Marchant A, Sayer J.

Dalton Trans. 2010 Sep 7;39(33):7747-59. doi: 10.1039/c0dt00360c. Epub 2010 Jul 26.

PMID:
20657943
8.

DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)].

Brabec V, Christofis P, Slámová M, Kostrhunová H, Nováková O, Najajreh Y, Gibson D, Kaspárková J.

Biochem Pharmacol. 2007 Jun 15;73(12):1887-900. Epub 2007 Mar 12.

PMID:
17400194
9.

Platinum metallodrug-protein binding studies by capillary electrophoresis-inductively coupled plasma-mass spectrometry: characterization of interactions between Pt(II) complexes and human serum albumin.

Timerbaev AR, Aleksenko SS, Polec-Pawlak K, Ruzik R, Semenova O, Hartinger CG, Oszwaldowski S, Galanski M, Jarosz M, Keppler BK.

Electrophoresis. 2004 Jul;25(13):1988-95.

PMID:
15237398
11.

Reactivity and biological properties of a series of cytotoxic PtI2(amine)2 complexes, either cis or trans configured.

Messori L, Cubo L, Gabbiani C, Álvarez-Valdés A, Michelucci E, Pieraccini G, Ríos-Luci C, León LG, Padrón JM, Navarro-Ranninger C, Casini A, Quiroga AG.

Inorg Chem. 2012 Feb 6;51(3):1717-26. doi: 10.1021/ic202036c. Epub 2012 Jan 6.

PMID:
22225466
13.

Synthesis, antitumor activity, and chemical properties of silaplatin and related platinum (II) and platinum (IV) complexes derived from beta-silyl amines.

Anderson WK, Kasliwal R, Houston DM, Wang YS, Narayanan VL, Haugwitz RD, Plowman J.

J Med Chem. 1995 Sep 15;38(19):3789-97.

PMID:
7562909
14.

Influence of (hydroxymethyl)pyridine and pyridine-carboxylic acids, in trans-position to the isopropylamine and amine ligands, on the cytotoxicity of platinum complexes.

Medina RM, Rodríguez J, Quiroga AG, Ramos-Lima FJ, Moneo V, Carnero A, Navarro-Ranninger C, Macazaga MJ.

Chem Biodivers. 2008 Oct;5(10):2090-100. doi: 10.1002/cbdv.200890190.

PMID:
18972499
15.

Reversion of structure-activity relationships of antitumor platinum complexes by acetoxime but not hydroxylamine ligands.

Zorbas-Seifried S, Jakupec MA, Kukushkin NV, Groessl M, Hartinger CG, Semenova O, Zorbas H, Kukushkin VY, Keppler BK.

Mol Pharmacol. 2007 Jan;71(1):357-65. Epub 2006 Oct 18.

16.

Three new asymmetric trans-amine(azole)dichloridoplatinum complexes that overcome cisplatin resistance and their reactions with 5'-GMP.

Pantoja E, Gallipoli A, van Zutphen S, Komeda S, Reddy D, Jaganyi D, Lutz M, Tooke DM, Spek AL, Navarro-Ranninger C, Reedijk J.

J Inorg Biochem. 2006 Dec;100(12):1955-64. Epub 2006 Sep 28.

PMID:
17083978
17.

Fluorescent analogues of quinoline reveal amine ligand loss from cis and trans platinum(II) complexes in cancer cells.

New EJ, Roche C, Madawala R, Zhang JZ, Hambley TW.

J Inorg Biochem. 2009 Aug;103(8):1120-5. doi: 10.1016/j.jinorgbio.2009.05.005. Epub 2009 May 21.

PMID:
19564043
18.

Modulation of drug activation profiles through carboxylate ligand modification in cytotoxic trans-platinum planar amine compounds.

Benedetti BT, Quintal S, Farrell NP.

Dalton Trans. 2011 Nov 7;40(41):10983-8. doi: 10.1039/c1dt10964b. Epub 2011 Sep 14.

PMID:
21918760
19.

Novel soluble cationic trans-diaminedichloroplatinum(II) complexes that are active against cisplatin resistant ovarian cancer cell lines.

Najajreh Y, Perez JM, Navarro-Ranninger C, Gibson D.

J Med Chem. 2002 Nov 21;45(24):5189-95.

PMID:
12431046
20.

Antitumor and cellular pharmacological properties of a novel platinum(IV) complex: trans-[PtCl(2)(OH)(2)(dimethylamine) (isopropylamine)].

Pérez JM, Kelland LR, Montero EI, Boxall FE, Fuertes MA, Alonso C, Navarro-Ranninger C.

Mol Pharmacol. 2003 Apr;63(4):933-44.

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