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Items: 1 to 20 of 107

1.

Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities.

Sivitz WI, Yorek MA.

Antioxid Redox Signal. 2010 Apr;12(4):537-77. doi: 10.1089/ars.2009.2531. Review.

2.

Mitochondrial superoxide and coenzyme Q in insulin-deficient rats: increased electron leak.

Herlein JA, Fink BD, Henry DM, Yorek MA, Teesch LM, Sivitz WI.

Am J Physiol Regul Integr Comp Physiol. 2011 Dec;301(6):R1616-24. doi: 10.1152/ajpregu.00395.2011. Epub 2011 Sep 21.

3.

Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes.

Lu H, Koshkin V, Allister EM, Gyulkhandanyan AV, Wheeler MB.

Diabetes. 2010 Feb;59(2):448-59. doi: 10.2337/db09-0129. Epub 2009 Nov 10.

4.

Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity.

Newsholme P, Haber EP, Hirabara SM, Rebelato EL, Procopio J, Morgan D, Oliveira-Emilio HC, Carpinelli AR, Curi R.

J Physiol. 2007 Aug 15;583(Pt 1):9-24. Epub 2007 Jun 21. Review.

5.

Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice.

Bonnard C, Durand A, Peyrol S, Chanseaume E, Chauvin MA, Morio B, Vidal H, Rieusset J.

J Clin Invest. 2008 Feb;118(2):789-800. doi: 10.1172/JCI32601.

6.

Mitochondrial dysfunction and complications associated with diabetes.

Blake R, Trounce IA.

Biochim Biophys Acta. 2014 Apr;1840(4):1404-12. doi: 10.1016/j.bbagen.2013.11.007. Epub 2013 Nov 15. Review.

PMID:
24246956
7.

Oxidative stress in skeletal muscle impairs mitochondrial respiration and limits exercise capacity in type 2 diabetic mice.

Yokota T, Kinugawa S, Hirabayashi K, Matsushima S, Inoue N, Ohta Y, Hamaguchi S, Sobirin MA, Ono T, Suga T, Kuroda S, Tanaka S, Terasaki F, Okita K, Tsutsui H.

Am J Physiol Heart Circ Physiol. 2009 Sep;297(3):H1069-77. doi: 10.1152/ajpheart.00267.2009. Epub 2009 Jul 17.

8.

Mitochondrial dysfunction leads to impairment of insulin sensitivity and adiponectin secretion in adipocytes.

Wang CH, Wang CC, Huang HC, Wei YH.

FEBS J. 2013 Feb;280(4):1039-50. doi: 10.1111/febs.12096. Epub 2013 Jan 27.

9.

Mitochondrial biogenesis: pharmacological approaches.

Valero T.

Curr Pharm Des. 2014;20(35):5507-9.

PMID:
24606795
10.

Long-term models of oxidative stress and mitochondrial damage in insulin resistance progression.

Graham EJ, Adler FR.

J Theor Biol. 2014 Jan 7;340:238-50. doi: 10.1016/j.jtbi.2013.09.028. Epub 2013 Sep 25.

PMID:
24076453
11.

Mitochondrial oxidative stress mediates high-phosphate-induced secretory defects and apoptosis in insulin-secreting cells.

Nguyen TT, Quan X, Hwang KH, Xu S, Das R, Choi SK, Wiederkehr A, Wollheim CB, Cha SK, Park KS.

Am J Physiol Endocrinol Metab. 2015 Jun 1;308(11):E933-41. doi: 10.1152/ajpendo.00009.2015. Epub 2015 Apr 7.

12.

Impairment of pancreatic β-cell function by chronic intermittent hypoxia.

Wang N, Khan SA, Prabhakar NR, Nanduri J.

Exp Physiol. 2013 Sep;98(9):1376-85. doi: 10.1113/expphysiol.2013.072454. Epub 2013 May 24.

13.

Oxidative stress and mitochondrial dysfunction in type 2 diabetes.

Victor VM, Rocha M, Herance R, Hernandez-Mijares A.

Curr Pharm Des. 2011 Dec 1;17(36):3947-58. Review.

PMID:
22188447
14.

Protective role of antioxidants in diabetes-induced cardiac dysfunction.

Vassort G, Turan B.

Cardiovasc Toxicol. 2010 Jun;10(2):73-86. doi: 10.1007/s12012-010-9064-0. Review.

PMID:
20458637
15.

Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.

Sharoyko VV, Abels M, Sun J, Nicholas LM, Mollet IG, Stamenkovic JA, Göhring I, Malmgren S, Storm P, Fadista J, Spégel P, Metodiev MD, Larsson NG, Eliasson L, Wierup N, Mulder H.

Hum Mol Genet. 2014 Nov 1;23(21):5733-49. doi: 10.1093/hmg/ddu288. Epub 2014 Jun 10.

PMID:
24916378
16.

Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus.

Ma ZA, Zhao Z, Turk J.

Exp Diabetes Res. 2012;2012:703538. doi: 10.1155/2012/703538. Epub 2011 Nov 9. Review.

17.

Mitochondrial respiratory chain dysfunction caused by coenzyme Q deficiency.

Rustin P, Munnich A, Rötig A.

Methods Enzymol. 2004;382:81-8. Review. No abstract available.

PMID:
15047097
18.

Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

Produit-Zengaffinen N, Davis-Lameloise N, Perreten H, Bécard D, Gjinovci A, Keller PA, Wollheim CB, Herrera P, Muzzin P, Assimacopoulos-Jeannet F.

Diabetologia. 2007 Jan;50(1):84-93. Epub 2006 Nov 28.

PMID:
17131143
20.

Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic beta-cells.

Sakai K, Matsumoto K, Nishikawa T, Suefuji M, Nakamaru K, Hirashima Y, Kawashima J, Shirotani T, Ichinose K, Brownlee M, Araki E.

Biochem Biophys Res Commun. 2003 Jan 3;300(1):216-22.

PMID:
12480546

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