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Items: 1 to 20 of 48


A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability.

Paulsen RD, Soni DV, Wollman R, Hahn AT, Yee MC, Guan A, Hesley JA, Miller SC, Cromwell EF, Solow-Cordero DE, Meyer T, Cimprich KA.

Mol Cell. 2009 Jul 31;35(2):228-39. doi: 10.1016/j.molcel.2009.06.021.


A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation.

Benzina S, Pitaval A, Lemercier C, Lustremant C, Frouin V, Wu N, Papine A, Soussaline F, Romeo PH, Gidrol X.

Cell Mol Life Sci. 2015 Sep;72(18):3559-73. doi: 10.1007/s00018-015-1901-7. Epub 2015 Apr 18.


A whole genome RNAi screen identifies replication stress response genes.

Kavanaugh G, Ye F, Mohni KN, Luzwick JW, Glick G, Cortez D.

DNA Repair (Amst). 2015 Nov;35:55-62. doi: 10.1016/j.dnarep.2015.09.024. Epub 2015 Sep 26.


PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase.

Tardat M, Murr R, Herceg Z, Sardet C, Julien E.

J Cell Biol. 2007 Dec 31;179(7):1413-26. Epub 2007 Dec 24.


ATR and H2AX cooperate in maintaining genome stability under replication stress.

Chanoux RA, Yin B, Urtishak KA, Asare A, Bassing CH, Brown EJ.

J Biol Chem. 2009 Feb 27;284(9):5994-6003. doi: 10.1074/jbc.M806739200. Epub 2008 Dec 2.


DNA damage response.

Giglia-Mari G, Zotter A, Vermeulen W.

Cold Spring Harb Perspect Biol. 2011 Jan 1;3(1):a000745. doi: 10.1101/cshperspect.a000745. Review.


Histone H2AX phosphorylation after cell irradiation with UV-B: relationship to cell cycle phase and induction of apoptosis.

Halicka HD, Huang X, Traganos F, King MA, Dai W, Darzynkiewicz Z.

Cell Cycle. 2005 Feb;4(2):339-45. Epub 2005 Feb 21.


A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation.

Papageorgiou A, Rapley J, Mesirov JP, Tamayo P, Avruch J.

PLoS One. 2015 Mar 19;10(3):e0116096. doi: 10.1371/journal.pone.0116096. eCollection 2015.


Triplex-induced DNA damage response.

Rogers FA, Tiwari MK.

Yale J Biol Med. 2013 Dec 13;86(4):471-8.


Leveraging DNA damage response signaling to identify yeast genes controlling genome stability.

Hendry JA, Tan G, Ou J, Boone C, Brown GW.

G3 (Bethesda). 2015 Feb 26;5(5):997-1006. doi: 10.1534/g3.115.016576.


Replication independent DNA double-strand break retention may prevent genomic instability.

Kongruttanachok N, Phuangphairoj C, Thongnak A, Ponyeam W, Rattanatanyong P, Pornthanakasem W, Mutirangura A.

Mol Cancer. 2010 Mar 31;9:70. doi: 10.1186/1476-4598-9-70.


Subnuclear domain proteins in cancer cells support the functions of RUNX2 in the DNA damage response.

Yang S, Quaresma AJ, Nickerson JA, Green KM, Shaffer SA, Imbalzano AN, Martin-Buley LA, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

J Cell Sci. 2015 Feb 15;128(4):728-40. doi: 10.1242/jcs.160051. Epub 2015 Jan 20.


DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein.

An J, Yang DY, Xu QZ, Zhang SM, Huo YY, Shang ZF, Wang Y, Wu DC, Zhou PK.

Mol Cancer. 2008 Apr 22;7:32. doi: 10.1186/1476-4598-7-32.


Quantification of gammaH2AX foci in response to ionising radiation.

Mah LJ, Vasireddy RS, Tang MM, Georgiadis GT, El-Osta A, Karagiannis TC.

J Vis Exp. 2010 Apr 6;(38). pii: 1957. doi: 10.3791/1957.


Human TopBP1 ensures genome integrity during normal S phase.

Kim JE, McAvoy SA, Smith DI, Chen J.

Mol Cell Biol. 2005 Dec;25(24):10907-15.


Genetic epidemiology of Charcot-Marie-Tooth disease.

Braathen GJ.

Acta Neurol Scand Suppl. 2012;(193):iv-22. doi: 10.1111/ane.12013.


MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.

Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, Jackson SP.

Cell. 2005 Dec 29;123(7):1213-26. Erratum in: Cell. 2008 May 2;133(3):549.


Charcot-Marie-Tooth disease and related inherited neuropathies.

Murakami T, Garcia CA, Reiter LT, Lupski JR.

Medicine (Baltimore). 1996 Sep;75(5):233-50. Review.


Widespread phosphorylation of histone H2AX by species C adenovirus infection requires viral DNA replication.

Nichols GJ, Schaack J, Ornelles DA.

J Virol. 2009 Jun;83(12):5987-98. doi: 10.1128/JVI.00091-09. Epub 2009 Mar 25.


Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition.

Arima Y, Hirota T, Bronner C, Mousli M, Fujiwara T, Niwa S, Ishikawa H, Saya H.

Genes Cells. 2004 Feb;9(2):131-42.

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