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Items: 1 to 20 of 282

1.

Epigenetic mechanisms of regulation of Foxp3 expression.

Lal G, Bromberg JS.

Blood. 2009 Oct 29;114(18):3727-35. doi: 10.1182/blood-2009-05-219584. Epub 2009 Jul 29. Review.

2.

Non-small-cell lung cancer-induced immunosuppression by increased human regulatory T cells via Foxp3 promoter demethylation.

Ke X, Zhang S, Xu J, Liu G, Zhang L, Xie E, Gao L, Li D, Sun R, Wang F, Pan S.

Cancer Immunol Immunother. 2016 May;65(5):587-99. doi: 10.1007/s00262-016-1825-6. Epub 2016 Mar 21.

PMID:
27000869
3.

Defective regulatory and effector T cell functions in patients with FOXP3 mutations.

Bacchetta R, Passerini L, Gambineri E, Dai M, Allan SE, Perroni L, Dagna-Bricarelli F, Sartirana C, Matthes-Martin S, Lawitschka A, Azzari C, Ziegler SF, Levings MK, Roncarolo MG.

J Clin Invest. 2006 Jun;116(6):1713-22.

4.

Demethylation analysis of the FOXP3 locus shows quantitative defects of regulatory T cells in IPEX-like syndrome.

Barzaghi F, Passerini L, Gambineri E, Ciullini Mannurita S, Cornu T, Kang ES, Choe YH, Cancrini C, Corrente S, Ciccocioppo R, Cecconi M, Zuin G, Discepolo V, Sartirana C, Schmidtko J, Ikinciogullari A, Ambrosi A, Roncarolo MG, Olek S, Bacchetta R.

J Autoimmun. 2012 Feb;38(1):49-58. doi: 10.1016/j.jaut.2011.12.009. Epub 2012 Jan 20.

5.

Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation.

Lal G, Zhang N, van der Touw W, Ding Y, Ju W, Bottinger EP, Reid SP, Levy DE, Bromberg JS.

J Immunol. 2009 Jan 1;182(1):259-73.

6.

Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development.

Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY, Stray-Pedersen A, Ocheltree EL, Greenberg PD, Ochs HD, Rudensky AY.

Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6659-64. Epub 2006 Apr 14. Erratum in: Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9373.

7.

Identification of FOXP3-negative regulatory T-like (CD4(+)CD25(+)CD127(low)) cells in patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.

Otsubo K, Kanegane H, Kamachi Y, Kobayashi I, Tsuge I, Imaizumi M, Sasahara Y, Hayakawa A, Nozu K, Iijima K, Ito S, Horikawa R, Nagai Y, Takatsu K, Mori H, Ochs HD, Miyawaki T.

Clin Immunol. 2011 Oct;141(1):111-20. doi: 10.1016/j.clim.2011.06.006. Epub 2011 Jul 12.

PMID:
21802372
8.

Anti-CD4 treatment inhibits autoimmunity in scurfy mice through the attenuation of co-stimulatory signals.

Mayer CT, Tian L, Hesse C, Kühl AA, Swallow M, Kruse F, Thiele M, Gershwin ME, Liston A, Sparwasser T.

J Autoimmun. 2014 May;50:23-32. doi: 10.1016/j.jaut.2013.08.010. Epub 2013 Sep 25.

PMID:
24075450
9.

Identification and characterization of Foxp3(+) gammadelta T cells in mouse and human.

Kang N, Tang L, Li X, Wu D, Li W, Chen X, Cui L, Ba D, He W.

Immunol Lett. 2009 Aug 15;125(2):105-13. doi: 10.1016/j.imlet.2009.06.005. Epub 2009 Jun 17.

PMID:
19539651
10.

Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells.

Nagar M, Vernitsky H, Cohen Y, Dominissini D, Berkun Y, Rechavi G, Amariglio N, Goldstein I.

Int Immunol. 2008 Aug;20(8):1041-55. doi: 10.1093/intimm/dxn062. Epub 2008 Jun 20.

PMID:
18567616
11.

IPEX and the role of Foxp3 in the development and function of human Tregs.

Le Bras S, Geha RS.

J Clin Invest. 2006 Jun;116(6):1473-5.

13.

Developmental changes of FOXP3-expressing CD4+CD25+ regulatory T cells and their impairment in patients with FOXP3 gene mutations.

Fuchizawa T, Adachi Y, Ito Y, Higashiyama H, Kanegane H, Futatani T, Kobayashi I, Kamachi Y, Sakamoto T, Tsuge I, Tanaka H, Banham AH, Ochs HD, Miyawaki T.

Clin Immunol. 2007 Dec;125(3):237-46. Epub 2007 Oct 3.

PMID:
17916446
14.

Point mutants of forkhead box P3 that cause immune dysregulation, polyendocrinopathy, enteropathy, X-linked have diverse abilities to reprogram T cells into regulatory T cells.

McMurchy AN, Gillies J, Allan SE, Passerini L, Gambineri E, Roncarolo MG, Bacchetta R, Levings MK.

J Allergy Clin Immunol. 2010 Dec;126(6):1242-51. doi: 10.1016/j.jaci.2010.09.001. Epub 2010 Oct 30.

PMID:
21036387
15.

Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome.

Passerini L, Di Nunzio S, Gregori S, Gambineri E, Cecconi M, Seidel MG, Cazzola G, Perroni L, Tommasini A, Vignola S, Guidi L, Roncarolo MG, Bacchetta R.

Eur J Immunol. 2011 Apr;41(4):1120-31. doi: 10.1002/eji.201040909. Epub 2011 Mar 14.

16.

Epigenetic control of the foxp3 locus in regulatory T cells.

Floess S, Freyer J, Siewert C, Baron U, Olek S, Polansky J, Schlawe K, Chang HD, Bopp T, Schmitt E, Klein-Hessling S, Serfling E, Hamann A, Huehn J.

PLoS Biol. 2007 Feb;5(2):e38.

17.

Peroxisome proliferator-activated receptor α and γ agonists together with TGF-β convert human CD4+CD25- T cells into functional Foxp3+ regulatory T cells.

Lei J, Hasegawa H, Matsumoto T, Yasukawa M.

J Immunol. 2010 Dec 15;185(12):7186-98. doi: 10.4049/jimmunol.1001437. Epub 2010 Nov 5.

18.

Clinical and molecular characteristics of immunodysregulation, polyendocrinopathy, enteropathy, X-linked syndrome in China.

An YF, Xu F, Wang M, Zhang ZY, Zhao XD.

Scand J Immunol. 2011 Sep;74(3):304-309. doi: 10.1111/j.1365-3083.2011.02574.x.

19.

Hypomethylation of the Treg-Specific Demethylated Region in FOXP3 Is a Hallmark of the Regulatory T-cell Subtype in Adult T-cell Leukemia.

Shimazu Y, Shimazu Y, Hishizawa M, Hamaguchi M, Nagai Y, Sugino N, Fujii S, Kawahara M, Kadowaki N, Nishikawa H, Sakaguchi S, Takaori-Kondo A.

Cancer Immunol Res. 2016 Feb;4(2):136-45. doi: 10.1158/2326-6066.CIR-15-0148. Epub 2015 Dec 17.

20.

Distinct regulatory roles of transforming growth factor-beta and interleukin-4 in the development and maintenance of natural and induced CD4+ CD25+ Foxp3+ regulatory T cells.

Prochazkova J, Fric J, Pokorna K, Neuwirth A, Krulova M, Zajicova A, Holan V.

Immunology. 2009 Sep;128(1 Suppl):e670-8. doi: 10.1111/j.1365-2567.2009.03060.x. Epub 2009 Jan 24.

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