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Items: 1 to 20 of 101

1.

Systems genetics analysis of cancer susceptibility: from mouse models to humans.

Quigley D, Balmain A.

Nat Rev Genet. 2009 Sep;10(9):651-7. doi: 10.1038/nrg2617. Epub 2009 Jul 28. Review.

PMID:
19636343
2.

Genomic approaches to identification of tumour-susceptibility genes using mouse models.

Mao JH, Balmain A.

Curr Opin Genet Dev. 2003 Feb;13(1):14-9. Review.

PMID:
12573430
3.
4.

Systems genetics approaches to understand complex traits.

Civelek M, Lusis AJ.

Nat Rev Genet. 2014 Jan;15(1):34-48. doi: 10.1038/nrg3575. Epub 2013 Dec 3. Review.

5.

Systems biology and the analysis of genetic variation.

Sunyaev SR, Roth FP.

Curr Opin Genet Dev. 2013 Dec;23(6):599-601. doi: 10.1016/j.gde.2013.11.010. Epub 2013 Nov 28. No abstract available.

6.

From mouse genetics to systems biology.

Balling R.

Mamm Genome. 2007 Jul;18(6-7):383-8. Epub 2007 Aug 1. No abstract available.

7.

The genetics of cancer susceptibility: from mouse to man.

Ewart-Toland A, Balmain A.

Toxicol Pathol. 2004 Mar-Apr;32 Suppl 1:26-30. Review.

PMID:
15209400
8.

Complexities of cancer research: mouse genetic models.

Hunter KW, Williams RW.

ILAR J. 2002;43(2):80-8. Review.

PMID:
11917159
9.

Systems genetics of alcoholism.

Sloan CD, Sayarath V, Moore JH.

Alcohol Res Health. 2008;31(1):14-25. Review.

10.

Novel approaches to identify low-penetrance cancer susceptibility genes using mouse models.

de Koning JP, Mao JH, Balmain A.

Recent Results Cancer Res. 2003;163:19-27; discussion 264-6. Review.

PMID:
12903840
11.

Most lung and colon cancer susceptibility genes are pair-wise linked in mice, humans and rats.

Quan L, Stassen AP, Ruivenkamp CA, van Wezel T, Fijneman RJ, Hutson A, Kakarlapudi N, Hart AA, Demant P.

PLoS One. 2011 Feb 24;6(2):e14727. doi: 10.1371/journal.pone.0014727.

12.

Exploring multiple quantitative trait loci models of hepatic fibrosis in a mouse intercross.

Hall RA, Hillebrandt S, Lammert F.

Mamm Genome. 2016 Feb;27(1-2):70-80. doi: 10.1007/s00335-015-9609-4. Epub 2015 Nov 7.

PMID:
26547557
13.

Systems genetics of susceptibility to obesity-induced diabetes in mice.

Davis RC, van Nas A, Castellani LW, Zhao Y, Zhou Z, Wen P, Yu S, Qi H, Rosales M, Schadt EE, Broman KW, Péterfy M, Lusis AJ.

Physiol Genomics. 2012 Jan 18;44(1):1-13. doi: 10.1152/physiolgenomics.00003.2011. Epub 2011 Oct 18.

14.

Mapping lupus susceptibility genes in the NZM2410 mouse model.

Morel L.

Adv Immunol. 2012;115:113-39. doi: 10.1016/B978-0-12-394299-9.00004-7. Review.

PMID:
22608257
15.

A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis.

Nakaoka H, Cui T, Tajima A, Oka A, Mitsunaga S, Kashiwase K, Homma Y, Sato S, Suzuki Y, Inoko H, Inoue I.

PLoS One. 2011;6(9):e25389. doi: 10.1371/journal.pone.0025389. Epub 2011 Sep 28.

16.

Limited evidence that cancer susceptibility regions are preferential targets for somatic mutation.

Machiela MJ, Ho BM, Fisher VA, Hua X, Chanock SJ.

Genome Biol. 2015 Sep 15;16:193. doi: 10.1186/s13059-015-0755-5.

17.

Gene networks associated with conditional fear in mice identified using a systems genetics approach.

Park CC, Gale GD, de Jong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Khan AH, Eskin E, Horvath S, Lusis AJ, Ophoff RA, Smith DJ.

BMC Syst Biol. 2011 Mar 16;5:43. doi: 10.1186/1752-0509-5-43.

18.

Mouse models for genetic dissection of polygenic gastrointestinal diseases.

Hillebrandt S, Matern S, Lammert F.

Eur J Clin Invest. 2003 Feb;33(2):155-60. Review.

PMID:
12588290
19.

Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression.

Papeta N, Chan KT, Prakash S, Martino J, Kiryluk K, Ballard D, Bruggeman LA, Frankel R, Zheng Z, Klotman PE, Zhao H, D'Agati VD, Lifton RP, Gharavi AG.

J Clin Invest. 2009 May;119(5):1178-88. doi: 10.1172/JCI37131. Epub 2009 Apr 20.

20.

Genetic networks in the mouse retina: growth associated protein 43 and phosphatase tensin homolog network.

Freeman NE, Templeton JP, Orr WE, Lu L, Williams RW, Geisert EE.

Mol Vis. 2011;17:1355-72. Epub 2011 May 25.

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