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Items: 1 to 20 of 181

1.

Targeted manipulation of mammalian genomes using designed zinc finger nucleases.

Kandavelou K, Ramalingam S, London V, Mani M, Wu J, Alexeev V, Civin CI, Chandrasegaran S.

Biochem Biophys Res Commun. 2009 Oct 9;388(1):56-61. doi: 10.1016/j.bbrc.2009.07.112. Epub 2009 Jul 25.

2.

Creating designed zinc-finger nucleases with minimal cytotoxicity.

Ramalingam S, Kandavelou K, Rajenderan R, Chandrasegaran S.

J Mol Biol. 2011 Jan 21;405(3):630-41. doi: 10.1016/j.jmb.2010.10.043. Epub 2010 Nov 19.

3.

Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases.

Kawai N, Ochiai H, Sakuma T, Yamada L, Sawada H, Yamamoto T, Sasakura Y.

Dev Growth Differ. 2012 Jun;54(5):535-45. doi: 10.1111/j.1440-169X.2012.01355.x. Epub 2012 May 28.

PMID:
22640377
4.

Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).

Foley JE, Yeh JR, Maeder ML, Reyon D, Sander JD, Peterson RT, Joung JK.

PLoS One. 2009;4(2):e4348. doi: 10.1371/journal.pone.0004348. Epub 2009 Feb 9.

5.

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme.

Wang J, Friedman G, Doyon Y, Wang NS, Li CJ, Miller JC, Hua KL, Yan JJ, Babiarz JE, Gregory PD, Holmes MC.

Genome Res. 2012 Jul;22(7):1316-26. doi: 10.1101/gr.122879.111. Epub 2012 Mar 20.

6.

Genome editing with CompoZr custom zinc finger nucleases (ZFNs).

Hansen K, Coussens MJ, Sago J, Subramanian S, Gjoka M, Briner D.

J Vis Exp. 2012 Jun 14;(64):e3304. doi: 10.3791/3304.

7.

Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways.

Qi Y, Zhang Y, Zhang F, Baller JA, Cleland SC, Ryu Y, Starker CG, Voytas DF.

Genome Res. 2013 Mar;23(3):547-54. doi: 10.1101/gr.145557.112. Epub 2013 Jan 2.

8.

A toolbox and procedural notes for characterizing novel zinc finger nucleases for genome editing in plant cells.

Tovkach A, Zeevi V, Tzfira T.

Plant J. 2009 Feb;57(4):747-57. doi: 10.1111/j.1365-313X.2008.03718.x. Epub 2008 Nov 24.

9.

Obligate ligation-gated recombination (ObLiGaRe): custom-designed nuclease-mediated targeted integration through nonhomologous end joining.

Maresca M, Lin VG, Guo N, Yang Y.

Genome Res. 2013 Mar;23(3):539-46. doi: 10.1101/gr.145441.112. Epub 2012 Nov 14.

10.

In vivo genome editing restores haemostasis in a mouse model of haemophilia.

Li H, Haurigot V, Doyon Y, Li T, Wong SY, Bhagwat AS, Malani N, Anguela XM, Sharma R, Ivanciu L, Murphy SL, Finn JD, Khazi FR, Zhou S, Paschon DE, Rebar EJ, Bushman FD, Gregory PD, Holmes MC, High KA.

Nature. 2011 Jun 26;475(7355):217-21. doi: 10.1038/nature10177.

11.

Custom-designed molecular scissors for site-specific manipulation of the plant and mammalian genomes.

Kandavelou K, Chandrasegaran S.

Methods Mol Biol. 2009;544:617-36. doi: 10.1007/978-1-59745-483-4_40.

12.

Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases.

Cai Y, Bak RO, Mikkelsen JG.

Elife. 2014 Apr 24;3:e01911. doi: 10.7554/eLife.01911.

13.

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly.

Kim HJ, Lee HJ, Kim H, Cho SW, Kim JS.

Genome Res. 2009 Jul;19(7):1279-88. doi: 10.1101/gr.089417.108. Epub 2009 May 21.

14.

Custom-designed zinc finger nucleases: what is next?

Wu J, Kandavelou K, Chandrasegaran S.

Cell Mol Life Sci. 2007 Nov;64(22):2933-44. Review.

15.

Targeted chromosomal deletions in human cells using zinc finger nucleases.

Lee HJ, Kim E, Kim JS.

Genome Res. 2010 Jan;20(1):81-9. doi: 10.1101/gr.099747.109. Epub 2009 Dec 1.

16.

Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases.

Beumer KJ, Trautman JK, Bozas A, Liu JL, Rutter J, Gall JG, Carroll D.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19821-6. doi: 10.1073/pnas.0810475105. Epub 2008 Dec 8.

17.

AAV-mediated delivery of zinc finger nucleases targeting hepatitis B virus inhibits active replication.

Weber ND, Stone D, Sedlak RH, De Silva Feelixge HS, Roychoudhury P, Schiffer JT, Aubert M, Jerome KR.

PLoS One. 2014 May 14;9(5):e97579. doi: 10.1371/journal.pone.0097579. eCollection 2014.

18.

Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells.

Durai S, Mani M, Kandavelou K, Wu J, Porteus MH, Chandrasegaran S.

Nucleic Acids Res. 2005 Oct 26;33(18):5978-90. Print 2005. Review.

19.

Biological and biomedical applications of engineered nucleases.

Pan Y, Xiao L, Li AS, Zhang X, Sirois P, Zhang J, Li K.

Mol Biotechnol. 2013 Sep;55(1):54-62. doi: 10.1007/s12033-012-9613-9. Review.

PMID:
23089945
20.

Simultaneous screening and validation of effective zinc finger nucleases in yeast.

Wang L, Lin J, Zhang T, Xu K, Ren C, Zhang Z.

PLoS One. 2013 May 31;8(5):e64687. doi: 10.1371/journal.pone.0064687. Print 2013.

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