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Items: 1 to 20 of 101

1.

Effect of single-chain antibody targeting of the ligand-binding domain in the anaplastic lymphoma kinase receptor.

Stylianou DC, Auf der Maur A, Kodack DP, Henke RT, Hohn S, Toretsky JA, Riegel AT, Wellstein A.

Oncogene. 2009 Sep 17;28(37):3296-306. doi: 10.1038/onc.2009.184. Epub 2009 Jul 27.

2.

Enhanced antitumorigenic effects in glioblastoma on double targeting of pleiotrophin and its receptor ALK.

Grzelinski M, Steinberg F, Martens T, Czubayko F, Lamszus K, Aigner A.

Neoplasia. 2009 Feb;11(2):145-56.

3.

Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin.

Stoica GE, Kuo A, Aigner A, Sunitha I, Souttou B, Malerczyk C, Caughey DJ, Wen D, Karavanov A, Riegel AT, Wellstein A.

J Biol Chem. 2001 May 18;276(20):16772-9. Epub 2001 Feb 8.

4.

Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types.

Stoica GE, Kuo A, Powers C, Bowden ET, Sale EB, Riegel AT, Wellstein A.

J Biol Chem. 2002 Sep 27;277(39):35990-8. Epub 2002 Jul 16.

7.

Anaplastic lymphoma kinase: "Ligand Independent Activation" mediated by the PTN/RPTPβ/ζ signaling pathway.

Deuel TF.

Biochim Biophys Acta. 2013 Oct;1834(10):2219-23. doi: 10.1016/j.bbapap.2013.06.004. Epub 2013 Jun 15. Review.

PMID:
23777859
8.

Anti-apoptotic signaling of pleiotrophin through its receptor, anaplastic lymphoma kinase.

Bowden ET, Stoica GE, Wellstein A.

J Biol Chem. 2002 Sep 27;277(39):35862-8. Epub 2002 Jul 9.

9.

Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth.

Powers C, Aigner A, Stoica GE, McDonnell K, Wellstein A.

J Biol Chem. 2002 Apr 19;277(16):14153-8. Epub 2002 Jan 23.

10.

Anaplastic lymphoma kinase is expressed in different subtypes of human breast cancer.

Perez-Pinera P, Chang Y, Astudillo A, Mortimer J, Deuel TF.

Biochem Biophys Res Commun. 2007 Jun 29;358(2):399-403. Epub 2007 Apr 30.

11.

The receptor protein tyrosine phosphatase (RPTP)beta/zeta is expressed in different subtypes of human breast cancer.

Perez-Pinera P, Garcia-Suarez O, Menendez-Rodriguez P, Mortimer J, Chang Y, Astudillo A, Deuel TF.

Biochem Biophys Res Commun. 2007 Oct 12;362(1):5-10. Epub 2007 Jun 18.

12.

Expression and function of the receptor protein tyrosine phosphatase zeta and its ligand pleiotrophin in human astrocytomas.

Ulbricht U, Brockmann MA, Aigner A, Eckerich C, Müller S, Fillbrandt R, Westphal M, Lamszus K.

J Neuropathol Exp Neurol. 2003 Dec;62(12):1265-75.

PMID:
14692702
13.

Recruitment of insulin receptor substrate-1 and activation of NF-kappaB essential for midkine growth signaling through anaplastic lymphoma kinase.

Kuo AH, Stoica GE, Riegel AT, Wellstein A.

Oncogene. 2007 Feb 8;26(6):859-69. Epub 2006 Jul 31.

PMID:
16878150
14.

The pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells.

Koyama-Nasu R, Haruta R, Nasu-Nishimura Y, Taniue K, Katou Y, Shirahige K, Todo T, Ino Y, Mukasa A, Saito N, Matsui M, Takahashi R, Hoshino-Okubo A, Sugano H, Manabe E, Funato K, Akiyama T.

Oncogene. 2014 Apr 24;33(17):2236-44. doi: 10.1038/onc.2013.168. Epub 2013 May 20.

PMID:
23686309
15.

Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA).

Ouyang T, Bai RY, Bassermann F, von Klitzing C, Klumpen S, Miething C, Morris SW, Peschel C, Duyster J.

J Biol Chem. 2003 Aug 8;278(32):30028-36. Epub 2003 May 14.

16.

Pleiotrophin induces neurite outgrowth and up-regulates growth-associated protein (GAP)-43 mRNA through the ALK/GSK3beta/beta-catenin signaling in developing mouse neurons.

Yanagisawa H, Komuta Y, Kawano H, Toyoda M, Sango K.

Neurosci Res. 2010 Jan;66(1):111-6. doi: 10.1016/j.neures.2009.10.002. Epub 2009 Oct 13.

PMID:
19833155
17.

Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation.

Martínez-Torrecuadrada J, Cifuentes G, López-Serra P, Saenz P, Martínez A, Casal JI.

Clin Cancer Res. 2005 Sep 1;11(17):6280-90.

18.

Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma.

Carpenter EL, Haglund EA, Mace EM, Deng D, Martinez D, Wood AC, Chow AK, Weiser DA, Belcastro LT, Winter C, Bresler SC, Vigny M, Mazot P, Asgharzadeh S, Seeger RC, Zhao H, Guo R, Christensen JG, Orange JS, Pawel BR, Lemmon MA, Mossé YP.

Oncogene. 2012 Nov 15;31(46):4859-67. doi: 10.1038/onc.2011.647. Epub 2012 Jan 23. Erratum in: Oncogene. 2012 Nov 15;31(46):4888. Vigny, M [added]; Mazot, P [added].

19.

Ribozyme-targeting reveals the rate-limiting role of pleiotrophin in glioblastoma.

Grzelinski M, Bader N, Czubayko F, Aigner A.

Int J Cancer. 2005 Dec 20;117(6):942-51.

20.

The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration.

Voena C, Conte C, Ambrogio C, Boeri Erba E, Boccalatte F, Mohammed S, Jensen ON, Palestro G, Inghirami G, Chiarle R.

Cancer Res. 2007 May 1;67(9):4278-86. Erratum in: Cancer Res. 2016 Mar 15;76(6):1669.

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