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Items: 1 to 20 of 102

1.

Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome.

Fessler MB, Rudel LL, Brown JM.

Curr Opin Lipidol. 2009 Oct;20(5):379-85. doi: 10.1097/MOL.0b013e32832fa5c4. Review.

2.

Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discovery.

Brown JM, Rudel LL.

Curr Opin Lipidol. 2010 Jun;21(3):192-7. doi: 10.1097/MOL.0b013e32833854ac. Review.

3.

Saturated fatty acids trigger TLR4-mediated inflammatory response.

Rocha DM, Caldas AP, Oliveira LL, Bressan J, Hermsdorff HH.

Atherosclerosis. 2016 Jan;244:211-5. doi: 10.1016/j.atherosclerosis.2015.11.015. Epub 2015 Dec 2. Review.

PMID:
26687466
4.

Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis.

Brown JM, Chung S, Sawyer JK, Degirolamo C, Alger HM, Nguyen TM, Zhu X, Duong MN, Brown AL, Lord C, Shah R, Davis MA, Kelley K, Wilson MD, Madenspacher J, Fessler MB, Parks JS, Rudel LL.

Arterioscler Thromb Vasc Biol. 2010 Jan;30(1):24-30. doi: 10.1161/ATVBAHA.109.198036. Epub 2009 Oct 15.

5.

Polymorphisms in Toll-like receptor 4 are associated with factors of the metabolic syndrome and modify the association between dietary saturated fat and fasting high-density lipoprotein cholesterol.

Cuda C, Badawi A, Karmali M, El-Sohemy A.

Metabolism. 2011 Aug;60(8):1131-5. doi: 10.1016/j.metabol.2010.12.006. Epub 2011 Feb 8.

PMID:
21306745
6.

A high ratio of dietary n-3/n-6 polyunsaturated fatty acids improves obesity-linked inflammation and insulin resistance through suppressing activation of TLR4 in SD rats.

Liu HQ, Qiu Y, Mu Y, Zhang XJ, Liu L, Hou XH, Zhang L, Xu XN, Ji AL, Cao R, Yang RH, Wang F.

Nutr Res. 2013 Oct;33(10):849-58. doi: 10.1016/j.nutres.2013.07.004. Epub 2013 Aug 9.

PMID:
24074743
7.

Saturated fatty acids do not directly stimulate Toll-like receptor signaling.

Erridge C, Samani NJ.

Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1944-9. doi: 10.1161/ATVBAHA.109.194050. Epub 2009 Aug 6.

8.

Toll-like receptor status in obesity and metabolic syndrome: a translational perspective.

Jialal I, Kaur H, Devaraj S.

J Clin Endocrinol Metab. 2014 Jan;99(1):39-48. doi: 10.1210/jc.2013-3092. Epub 2013 Dec 20. Review.

PMID:
24187406
9.

The association between dietary saturated fatty acids and ischemic heart disease depends on the type and source of fatty acid in the European Prospective Investigation into Cancer and Nutrition-Netherlands cohort.

Praagman J, Beulens JW, Alssema M, Zock PL, Wanders AJ, Sluijs I, van der Schouw YT.

Am J Clin Nutr. 2016 Feb;103(2):356-65. doi: 10.3945/ajcn.115.122671. Epub 2016 Jan 20.

10.

Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis.

Brown JM, Chung S, Sawyer JK, Degirolamo C, Alger HM, Nguyen T, Zhu X, Duong MN, Wibley AL, Shah R, Davis MA, Kelley K, Wilson MD, Kent C, Parks JS, Rudel LL.

Circulation. 2008 Sep 30;118(14):1467-75. doi: 10.1161/CIRCULATIONAHA.108.793182. Epub 2008 Sep 15.

11.

Lipotoxicity: effects of dietary saturated and transfatty acids.

Estadella D, da Penha Oller do Nascimento CM, Oyama LM, Ribeiro EB, Dâmaso AR, de Piano A.

Mediators Inflamm. 2013;2013:137579. doi: 10.1155/2013/137579. Epub 2013 Jan 31.

12.
13.

Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity.

Kim F, Pham M, Luttrell I, Bannerman DD, Tupper J, Thaler J, Hawn TR, Raines EW, Schwartz MW.

Circ Res. 2007 Jun 8;100(11):1589-96. Epub 2007 May 3.

14.

Stearoyl-CoA desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes.

Matsui H, Yokoyama T, Sekiguchi K, Iijima D, Sunaga H, Maniwa M, Ueno M, Iso T, Arai M, Kurabayashi M.

PLoS One. 2012;7(3):e33283. doi: 10.1371/journal.pone.0033283. Epub 2012 Mar 8.

15.

Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome--LIPGENE: a European randomized dietary intervention study.

Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Gołąbek-Leszczyñska I, Defoort C, Williams CM, Karsltröm B, Vessby B, Dembinska-Kiec A, López-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM.

Int J Obes (Lond). 2011 Jun;35(6):800-9. doi: 10.1038/ijo.2010.209. Epub 2010 Oct 12.

PMID:
20938439
16.

The dual role of free fatty acid signaling in inflammation and therapeutics.

Volpe CM, Nogueira-Machado JA.

Recent Pat Endocr Metab Immune Drug Discov. 2013 Sep;7(3):189-97.

PMID:
23909843
17.
18.

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance.

Pal D, Dasgupta S, Kundu R, Maitra S, Das G, Mukhopadhyay S, Ray S, Majumdar SS, Bhattacharya S.

Nat Med. 2012 Aug;18(8):1279-85. doi: 10.1038/nm.2851. Epub 2012 Jul 29.

PMID:
22842477
19.

The association of desaturase 9 and plasma fatty acid composition with insulin resistance-associated factors in female adolescents.

Zhou YE, Egeland GM, Meltzer SJ, Kubow S.

Metabolism. 2009 Feb;58(2):158-66. doi: 10.1016/j.metabol.2008.09.008.

PMID:
19154947

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