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Items: 1 to 20 of 85

1.

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.

Ablasser A, Bauernfeind F, Hartmann G, Latz E, Fitzgerald KA, Hornung V.

Nat Immunol. 2009 Oct;10(10):1065-72. doi: 10.1038/ni.1779. Epub 2009 Jul 16.

2.

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling.

Miyashita M, Oshiumi H, Matsumoto M, Seya T.

Mol Cell Biol. 2011 Sep;31(18):3802-19. doi: 10.1128/MCB.01368-10. Epub 2011 Jul 26.

3.

Inhibition of the RNA polymerase III-mediated dsDNA-sensing pathway of innate immunity by vaccinia virus protein E3.

Valentine R, Smith GL.

J Gen Virol. 2010 Sep;91(Pt 9):2221-9. doi: 10.1099/vir.0.021998-0. Epub 2010 Jun 2.

4.

SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I.

Heutinck KM, Kassies J, Florquin S, ten Berge IJ, Hamann J, Rowshani AT.

Nephrol Dial Transplant. 2012 Jul;27(7):2746-54. doi: 10.1093/ndt/gfr690. Epub 2011 Dec 13.

PMID:
22167597
5.

Coexpressed RIG-I agonist enhances humoral immune response to influenza virus DNA vaccine.

Luke JM, Simon GG, Söderholm J, Errett JS, August JT, Gale M Jr, Hodgson CP, Williams JA.

J Virol. 2011 Feb;85(3):1370-83. doi: 10.1128/JVI.01250-10. Epub 2010 Nov 24.

6.

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway.

Chiu YH, Macmillan JB, Chen ZJ.

Cell. 2009 Aug 7;138(3):576-91. doi: 10.1016/j.cell.2009.06.015. Epub 2009 Jul 23.

7.

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J.

PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674.

8.

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.

Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB.

J Immunol. 2009 Dec 1;183(11):6989-97. doi: 10.4049/jimmunol.0901386. Epub 2009 Nov 4.

9.

DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formation.

Yoo JS, Takahasi K, Ng CS, Ouda R, Onomoto K, Yoneyama M, Lai JC, Lattmann S, Nagamine Y, Matsui T, Iwabuchi K, Kato H, Fujita T.

PLoS Pathog. 2014 Mar 20;10(3):e1004012. doi: 10.1371/journal.ppat.1004012. eCollection 2014 Mar.

10.

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.

Schlee M, Roth A, Hornung V, Hagmann CA, Wimmenauer V, Barchet W, Coch C, Janke M, Mihailovic A, Wardle G, Juranek S, Kato H, Kawai T, Poeck H, Fitzgerald KA, Takeuchi O, Akira S, Tuschl T, Latz E, Ludwig J, Hartmann G.

Immunity. 2009 Jul 17;31(1):25-34. doi: 10.1016/j.immuni.2009.05.008. Epub 2009 Jul 2.

11.

RAD23A negatively regulates RIG-I/MDA5 signaling through promoting TRAF2 polyubiquitination and degradation.

Fang DF, He K, Wang J, Mu R, Tan B, Jian Z, Li HY, Song W, Chang Y, Gong WL, Li WH, Wang GJ.

Biochem Biophys Res Commun. 2013 Feb 22;431(4):686-92. doi: 10.1016/j.bbrc.2013.01.059. Epub 2013 Jan 25.

PMID:
23357418
12.

The chase for the RIG-I ligand--recent advances.

Schlee M, Hartmann G.

Mol Ther. 2010 Jul;18(7):1254-62. doi: 10.1038/mt.2010.90. Epub 2010 May 11. Review.

13.

[Cell type specific involvement of RIG-I in antiviral responses].

Kato H, Takeuchi O, Akira S.

Nihon Rinsho. 2006 Jul;64(7):1244-7. Review. Japanese.

PMID:
16838639
14.

The double-stranded RNA-binding protein PACT functions as a cellular activator of RIG-I to facilitate innate antiviral response.

Kok KH, Lui PY, Ng MH, Siu KL, Au SW, Jin DY.

Cell Host Microbe. 2011 Apr 21;9(4):299-309. doi: 10.1016/j.chom.2011.03.007.

15.

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.

Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8.

16.

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5.

Kato H, Takeuchi O, Mikamo-Satoh E, Hirai R, Kawai T, Matsushita K, Hiiragi A, Dermody TS, Fujita T, Akira S.

J Exp Med. 2008 Jul 7;205(7):1601-10. doi: 10.1084/jem.20080091.

17.

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J.

Nature. 2005 Oct 20;437(7062):1167-72. Epub 2005 Sep 21.

PMID:
16177806
18.

Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5.

Li X, Lu C, Stewart M, Xu H, Strong RK, Igumenova T, Li P.

Arch Biochem Biophys. 2009 Aug 1;488(1):23-33. doi: 10.1016/j.abb.2009.06.008. Epub 2009 Jun 14.

PMID:
19531363
19.

Approaching the RNA ligand for RIG-I?

Schlee M, Hartmann E, Coch C, Wimmenauer V, Janke M, Barchet W, Hartmann G.

Immunol Rev. 2009 Jan;227(1):66-74. doi: 10.1111/j.1600-065X.2008.00724.x. Review.

PMID:
19120476
20.

Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors.

Takahasi K, Kumeta H, Tsuduki N, Narita R, Shigemoto T, Hirai R, Yoneyama M, Horiuchi M, Ogura K, Fujita T, Inagaki F.

J Biol Chem. 2009 Jun 26;284(26):17465-74. doi: 10.1074/jbc.M109.007179. Epub 2009 Apr 20.

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