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Lack of cocaine self-administration in mice expressing a cocaine-insensitive dopamine transporter.

Thomsen M, Han DD, Gu HH, Caine SB.

J Pharmacol Exp Ther. 2009 Oct;331(1):204-11. doi: 10.1124/jpet.109.156265.


Dramatically decreased cocaine self-administration in dopamine but not serotonin transporter knock-out mice.

Thomsen M, Hall FS, Uhl GR, Caine SB.

J Neurosci. 2009 Jan 28;29(4):1087-92. doi: 10.1523/JNEUROSCI.4037-08.2009.


Behavior of knock-in mice with a cocaine-insensitive dopamine transporter after virogenetic restoration of cocaine sensitivity in the striatum.

O'Neill B, Tilley MR, Han DD, Thirtamara-Rajamani K, Hill ER, Bishop GA, Zhou FM, During MJ, Gu HH.

Neuropharmacology. 2014 Apr;79:626-33. doi: 10.1016/j.neuropharm.2013.12.023.


Effects of dopamine transporter inhibitors on cocaine self-administration in rhesus monkeys: relationship to transporter occupancy determined by positron emission tomography neuroimaging.

Lindsey KP, Wilcox KM, Votaw JR, Goodman MM, Plisson C, Carroll FI, Rice KC, Howell LL.

J Pharmacol Exp Ther. 2004 Jun;309(3):959-69.


Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors.

Hiranita T, Soto PL, Kohut SJ, Kopajtic T, Cao J, Newman AH, Tanda G, Katz JL.

J Pharmacol Exp Ther. 2011 Nov;339(2):662-77. doi: 10.1124/jpet.111.185025.


The dopamine transporter expression level differentially affects responses to cocaine and amphetamine.

Cagniard B, Sotnikova TD, Gainetdinov RR, Zhuang X.

J Neurogenet. 2014 Mar-Jun;28(1-2):112-21. doi: 10.3109/01677063.2014.908191.


Cocaine and amphetamine increase extracellular dopamine in the nucleus accumbens of mice lacking the dopamine transporter gene.

Carboni E, Spielewoy C, Vacca C, Nosten-Bertrand M, Giros B, Di Chiara G.

J Neurosci. 2001 May 1;21(9):RC141: 1-4.


Attenuation of cocaine's reinforcing and discriminative stimulus effects via muscarinic M1 acetylcholine receptor stimulation.

Thomsen M, Conn PJ, Lindsley C, Wess J, Boon JY, Fulton BS, Fink-Jensen A, Caine SB.

J Pharmacol Exp Ther. 2010 Mar;332(3):959-69. doi: 10.1124/jpet.109.162057.


Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter.

Chen R, Tilley MR, Wei H, Zhou F, Zhou FM, Ching S, Quan N, Stephens RL, Hill ER, Nottoli T, Han DD, Gu HH.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9333-8.


Cocaine self-administration in dopamine-transporter knockout mice.

Rocha BA, Fumagalli F, Gainetdinov RR, Jones SR, Ator R, Giros B, Miller GW, Caron MG.

Nat Neurosci. 1998 Jun;1(2):132-7. Erratum in: Nat Neurosci 1998 Aug;1(4):330.


Progression of changes in dopamine transporter binding site density as a result of cocaine self-administration in rhesus monkeys.

Letchworth SR, Nader MA, Smith HR, Friedman DP, Porrino LJ.

J Neurosci. 2001 Apr 15;21(8):2799-807.


Phenotypic expression of the targeted null-mutation in the dopamine transporter gene varies as a function of the genetic background.

Morice E, Denis C, Giros B, Nosten-Bertrand M.

Eur J Neurosci. 2004 Jul;20(1):120-6.


Differential influence of dopamine transport rate on the potencies of cocaine, amphetamine, and methylphenidate.

Calipari ES, Ferris MJ, Siciliano CA, Jones SR.

ACS Chem Neurosci. 2015 Jan 21;6(1):155-62. doi: 10.1021/cn500262x.


Effects of combined dopamine and serotonin transporter inhibitors on cocaine self-administration in rhesus monkeys.

Howell LL, Carroll FI, Votaw JR, Goodman MM, Kimmel HL.

J Pharmacol Exp Ther. 2007 Feb;320(2):757-65.


Reinforcing strength of a novel dopamine transporter ligand: pharmacodynamic and pharmacokinetic mechanisms.

Woolverton WL, Ranaldi R, Wang Z, Ordway GA, Paul IA, Petukhov P, Kozikowski A.

J Pharmacol Exp Ther. 2002 Oct;303(1):211-7.


Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity.

Miller GM, Yatin SM, De La Garza R 2nd, Goulet M, Madras BK.

Brain Res Mol Brain Res. 2001 Feb 19;87(1):124-43.


Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.

Cao J, Kulkarni SS, Husbands SM, Bowen WD, Williams W, Kopajtic T, Katz JL, George C, Newman AH.

J Med Chem. 2003 Jun 19;46(13):2589-98.


The effects of cocaine on regional brain glucose metabolism is attenuated in dopamine transporter knockout mice.

Thanos PK, Michaelides M, Benveniste H, Wang GJ, Volkow ND.

Synapse. 2008 May;62(5):319-24. doi: 10.1002/syn.20503.

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