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Items: 1 to 20 of 221

1.

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition.

Vincent T, Neve EP, Johnson JR, Kukalev A, Rojo F, Albanell J, Pietras K, Virtanen I, Philipson L, Leopold PL, Crystal RG, de Herreros AG, Moustakas A, Pettersson RF, Fuxe J.

Nat Cell Biol. 2009 Aug;11(8):943-50. doi: 10.1038/ncb1905. Epub 2009 Jul 13.

2.

TGF-β-activated SMAD3/4 complex transcriptionally upregulates N-cadherin expression in non-small cell lung cancer.

Yang H, Wang L, Zhao J, Chen Y, Lei Z, Liu X, Xia W, Guo L, Zhang HT.

Lung Cancer. 2015 Mar;87(3):249-57. doi: 10.1016/j.lungcan.2014.12.015. Epub 2015 Jan 5.

PMID:
25595426
4.

Peroxisome proliferator-activated receptor-gamma activation inhibits tumor metastasis by antagonizing Smad3-mediated epithelial-mesenchymal transition.

Reka AK, Kurapati H, Narala VR, Bommer G, Chen J, Standiford TJ, Keshamouni VG.

Mol Cancer Ther. 2010 Dec;9(12):3221-32. doi: 10.1158/1535-7163.MCT-10-0570.

5.

HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition.

Thuault S, Tan EJ, Peinado H, Cano A, Heldin CH, Moustakas A.

J Biol Chem. 2008 Nov 28;283(48):33437-46. doi: 10.1074/jbc.M802016200. Epub 2008 Oct 1.

6.

A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition.

Smith AP, Verrecchia A, Fagà G, Doni M, Perna D, Martinato F, Guccione E, Amati B.

Oncogene. 2009 Jan 22;28(3):422-30. doi: 10.1038/onc.2008.395. Epub 2008 Nov 3.

PMID:
18978814
7.

Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition.

Zavadil J, Cermak L, Soto-Nieves N, Böttinger EP.

EMBO J. 2004 Mar 10;23(5):1155-65. Epub 2004 Feb 19.

8.

Differential role of Snail1 and Snail2 zinc fingers in E-cadherin repression and epithelial to mesenchymal transition.

Villarejo A, Cortés-Cabrera A, Molina-Ortíz P, Portillo F, Cano A.

J Biol Chem. 2014 Jan 10;289(2):930-41. doi: 10.1074/jbc.M113.528026. Epub 2013 Dec 1.

9.

Cooperative involvement of NFAT and SnoN mediates transforming growth factor-β (TGF-β) induced EMT in metastatic breast cancer (MDA-MB 231) cells.

Sengupta S, Jana S, Biswas S, Mandal PK, Bhattacharyya A.

Clin Exp Metastasis. 2013 Dec;30(8):1019-31. doi: 10.1007/s10585-013-9600-y. Epub 2013 Jul 6.

PMID:
23832742
10.

Endothelin-1 promotes epithelial-to-mesenchymal transition in human ovarian cancer cells.

Rosanò L, Spinella F, Di Castro V, Nicotra MR, Dedhar S, de Herreros AG, Natali PG, Bagnato A.

Cancer Res. 2005 Dec 15;65(24):11649-57.

11.

Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis.

Xue J, Lin X, Chiu WT, Chen YH, Yu G, Liu M, Feng XH, Sawaya R, Medema RH, Hung MC, Huang S.

J Clin Invest. 2014 Feb;124(2):564-79. doi: 10.1172/JCI71104. Epub 2014 Jan 2.

12.

Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion.

Wang X, Zheng M, Liu G, Xia W, McKeown-Longo PJ, Hung MC, Zhao J.

Cancer Res. 2007 Aug 1;67(15):7184-93.

13.

Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes.

Franco DL, Mainez J, Vega S, Sancho P, Murillo MM, de Frutos CA, Del Castillo G, López-Blau C, Fabregat I, Nieto MA.

J Cell Sci. 2010 Oct 15;123(Pt 20):3467-77. doi: 10.1242/jcs.068692.

14.

Functional cooperation between Snail1 and twist in the regulation of ZEB1 expression during epithelial to mesenchymal transition.

Dave N, Guaita-Esteruelas S, Gutarra S, Frias À, Beltran M, Peiró S, de Herreros AG.

J Biol Chem. 2011 Apr 8;286(14):12024-32. doi: 10.1074/jbc.M110.168625. Epub 2011 Feb 12.

15.

Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence.

Tran DD, Corsa CA, Biswas H, Aft RL, Longmore GD.

Mol Cancer Res. 2011 Dec;9(12):1644-57. doi: 10.1158/1541-7786.MCR-11-0371. Epub 2011 Oct 17.

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18.

c-Jun N-terminal kinase 1 promotes transforming growth factor-β1-induced epithelial-to-mesenchymal transition via control of linker phosphorylation and transcriptional activity of Smad3.

Velden JL, Alcorn JF, Guala AS, Badura EC, Janssen-Heininger YM.

Am J Respir Cell Mol Biol. 2011 Apr;44(4):571-81. doi: 10.1165/rcmb.2009-0282OC. Epub 2010 Jun 25.

19.

p70 S6 kinase promotes epithelial to mesenchymal transition through snail induction in ovarian cancer cells.

Pon YL, Zhou HY, Cheung AN, Ngan HY, Wong AS.

Cancer Res. 2008 Aug 15;68(16):6524-32. doi: 10.1158/0008-5472.CAN-07-6302.

20.

Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells.

Boudreau HE, Casterline BW, Rada B, Korzeniowska A, Leto TL.

Free Radic Biol Med. 2012 Oct 1;53(7):1489-99. doi: 10.1016/j.freeradbiomed.2012.06.016. Epub 2012 Jun 19.

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