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Items: 1 to 20 of 121

1.

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.

Fekairi S, Scaglione S, Chahwan C, Taylor ER, Tissier A, Coulon S, Dong MQ, Ruse C, Yates JR 3rd, Russell P, Fuchs RP, McGowan CH, Gaillard PH.

Cell. 2009 Jul 10;138(1):78-89. doi: 10.1016/j.cell.2009.06.029.

2.

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

Svendsen JM, Smogorzewska A, Sowa ME, O'Connell BC, Gygi SP, Elledge SJ, Harper JW.

Cell. 2009 Jul 10;138(1):63-77. doi: 10.1016/j.cell.2009.06.030.

3.

Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.

Muñoz IM, Hain K, Déclais AC, Gardiner M, Toh GW, Sanchez-Pulido L, Heuckmann JM, Toth R, Macartney T, Eppink B, Kanaar R, Ponting CP, Lilley DM, Rouse J.

Mol Cell. 2009 Jul 10;35(1):116-27. doi: 10.1016/j.molcel.2009.06.020.

4.

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination.

Andersen SL, Bergstralh DT, Kohl KP, LaRocque JR, Moore CB, Sekelsky J.

Mol Cell. 2009 Jul 10;35(1):128-35. doi: 10.1016/j.molcel.2009.06.019.

5.

Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells.

Wyatt HD, Sarbajna S, Matos J, West SC.

Mol Cell. 2013 Oct 24;52(2):234-47. doi: 10.1016/j.molcel.2013.08.035. Epub 2013 Sep 26.

6.

Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.

Castor D, Nair N, Déclais AC, Lachaud C, Toth R, Macartney TJ, Lilley DM, Arthur JS, Rouse J.

Mol Cell. 2013 Oct 24;52(2):221-33. doi: 10.1016/j.molcel.2013.08.036. Epub 2013 Sep 26.

7.

The SMX DNA Repair Tri-nuclease.

Wyatt HD, Laister RC, Martin SR, Arrowsmith CH, West SC.

Mol Cell. 2017 Mar 2;65(5):848-860.e11. doi: 10.1016/j.molcel.2017.01.031.

8.

Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions.

Garner E, Kim Y, Lach FP, Kottemann MC, Smogorzewska A.

Cell Rep. 2013 Oct 17;5(1):207-15. doi: 10.1016/j.celrep.2013.08.041. Epub 2013 Sep 27.

9.

SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres.

Wan B, Yin J, Horvath K, Sarkar J, Chen Y, Wu J, Wan K, Lu J, Gu P, Yu EY, Lue NF, Chang S, Liu Y, Lei M.

Cell Rep. 2013 Sep 12;4(5):861-9. doi: 10.1016/j.celrep.2013.08.017. Epub 2013 Sep 5.

10.

SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr).

Zhou X, DeLucia M, Ahn J.

J Biol Chem. 2016 Aug 12;291(33):16936-16947. doi: 10.1074/jbc.M116.721183. Epub 2016 Jun 27.

11.

Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.

Yamamoto KN, Kobayashi S, Tsuda M, Kurumizaka H, Takata M, Kono K, Jiricny J, Takeda S, Hirota K.

Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6492-6. doi: 10.1073/pnas.1018487108. Epub 2011 Apr 4.

12.

Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair.

Hodskinson MR, Silhan J, Crossan GP, Garaycoechea JI, Mukherjee S, Johnson CM, Schärer OD, Patel KJ.

Mol Cell. 2014 May 8;54(3):472-84. doi: 10.1016/j.molcel.2014.03.014. Epub 2014 Apr 10.

13.

Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein.

Nair N, Castor D, Macartney T, Rouse J.

DNA Repair (Amst). 2014 Dec;24:131-137. doi: 10.1016/j.dnarep.2014.08.004. Epub 2014 Sep 16.

14.

Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes.

Schwartz EK, Heyer WD.

Chromosoma. 2011 Apr;120(2):109-27. doi: 10.1007/s00412-010-0304-7. Epub 2011 Jan 11. Review. Erratum in: Chromosoma. 2011 Aug;120(4):423-4.

15.

Disruption of SLX4-MUS81 Function Increases the Relative Biological Effectiveness of Proton Radiation.

Liu Q, Underwood TS, Kung J, Wang M, Lu HM, Paganetti H, Held KD, Hong TS, Efstathiou JA, Willers H.

Int J Radiat Oncol Biol Phys. 2016 May 1;95(1):78-85. doi: 10.1016/j.ijrobp.2016.01.046. Epub 2016 Feb 1.

16.

Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe.

Sarbajna S, Davies D, West SC.

Genes Dev. 2014 May 15;28(10):1124-36. doi: 10.1101/gad.238303.114.

17.

Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4.

Kim Y, Spitz GS, Veturi U, Lach FP, Auerbach AD, Smogorzewska A.

Blood. 2013 Jan 3;121(1):54-63. doi: 10.1182/blood-2012-07-441212. Epub 2012 Oct 23.

18.

Structure and mechanism of nucleases regulated by SLX4.

Nowotny M, Gaur V.

Curr Opin Struct Biol. 2016 Feb;36:97-105. doi: 10.1016/j.sbi.2016.01.003. Epub 2016 Jan 29. Review.

PMID:
26827285
19.

Mus81-Eme1 are essential components of a Holliday junction resolvase.

Boddy MN, Gaillard PH, McDonald WH, Shanahan P, Yates JR 3rd, Russell P.

Cell. 2001 Nov 16;107(4):537-48.

20.

RNA interference inhibition of Mus81 reduces mitotic recombination in human cells.

Blais V, Gao H, Elwell CA, Boddy MN, Gaillard PH, Russell P, McGowan CH.

Mol Biol Cell. 2004 Feb;15(2):552-62. Epub 2003 Nov 14.

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