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Items: 1 to 20 of 221

1.

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases.

Uversky VN, Oldfield CJ, Midic U, Xie H, Xue B, Vucetic S, Iakoucheva LM, Obradovic Z, Dunker AK.

BMC Genomics. 2009 Jul 7;10 Suppl 1:S7. doi: 10.1186/1471-2164-10-S1-S7.

2.

The unfoldomics decade: an update on intrinsically disordered proteins.

Dunker AK, Oldfield CJ, Meng J, Romero P, Yang JY, Chen JW, Vacic V, Obradovic Z, Uversky VN.

BMC Genomics. 2008 Sep 16;9 Suppl 2:S1. doi: 10.1186/1471-2164-9-S2-S1.

3.

The mysterious unfoldome: structureless, underappreciated, yet vital part of any given proteome.

Uversky VN.

J Biomed Biotechnol. 2010;2010:568068. doi: 10.1155/2010/568068. Epub . Review.

4.

Protein disorder in the human diseasome: unfoldomics of human genetic diseases.

Midic U, Oldfield CJ, Dunker AK, Obradovic Z, Uversky VN.

BMC Genomics. 2009 Jul 7;10 Suppl 1:S12. doi: 10.1186/1471-2164-10-S1-S12.

5.

Unfoldomics of human genetic diseases: illustrative examples of ordered and intrinsically disordered members of the human diseasome.

Midic U, Oldfield CJ, Dunker AK, Obradovic Z, Uversky VN.

Protein Pept Lett. 2009;16(12):1533-47. Review.

PMID:
20001916
6.

Intrinsically disordered proteins in human diseases: introducing the D2 concept.

Uversky VN, Oldfield CJ, Dunker AK.

Annu Rev Biophys. 2008;37:215-46. doi: 10.1146/annurev.biophys.37.032807.125924. Review.

PMID:
18573080
7.

Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery.

Rezaei-Ghaleh N, Blackledge M, Zweckstetter M.

Chembiochem. 2012 May 7;13(7):930-50. doi: 10.1002/cbic.201200093. Epub 2012 Apr 13. Review.

PMID:
22505141
8.

Archaic chaos: intrinsically disordered proteins in Archaea.

Xue B, Williams RW, Oldfield CJ, Dunker AK, Uversky VN.

BMC Syst Biol. 2010 May 28;4 Suppl 1:S1. doi: 10.1186/1752-0509-4-S1-S1.

9.

Protein intrinsic disorder and human papillomaviruses: increased amount of disorder in E6 and E7 oncoproteins from high risk HPVs.

Uversky VN, Roman A, Oldfield CJ, Dunker AK.

J Proteome Res. 2006 Aug;5(8):1829-42.

PMID:
16889404
10.

Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.

Xie H, Vucetic S, Iakoucheva LM, Oldfield CJ, Dunker AK, Obradovic Z, Uversky VN.

J Proteome Res. 2007 May;6(5):1917-32. Epub 2007 Mar 29.

11.

Limitations of induced folding in molecular recognition by intrinsically disordered proteins.

Hazy E, Tompa P.

Chemphyschem. 2009 Jul 13;10(9-10):1415-9. doi: 10.1002/cphc.200900205. Review.

PMID:
19462392
12.

Towards the physical basis of how intrinsic disorder mediates protein function.

Chen J.

Arch Biochem Biophys. 2012 Aug 15;524(2):123-31. doi: 10.1016/j.abb.2012.04.024. Epub 2012 May 9. Review.

PMID:
22579883
13.

GRAS proteins: the versatile roles of intrinsically disordered proteins in plant signalling.

Sun X, Jones WT, Rikkerink EH.

Biochem J. 2012 Feb 15;442(1):1-12. doi: 10.1042/BJ20111766. Review.

PMID:
22280012
14.

Markov models of amino acid substitution to study proteins with intrinsically disordered regions.

Szalkowski AM, Anisimova M.

PLoS One. 2011;6(5):e20488. doi: 10.1371/journal.pone.0020488. Epub 2011 May 27.

15.

Predicting intrinsic disorder in proteins: an overview.

He B, Wang K, Liu Y, Xue B, Uversky VN, Dunker AK.

Cell Res. 2009 Aug;19(8):929-49. doi: 10.1038/cr.2009.87. Review.

PMID:
19597536
16.

Advantages of proteins being disordered.

Liu Z, Huang Y.

Protein Sci. 2014 May;23(5):539-50. doi: 10.1002/pro.2443. Epub 2014 Mar 17. Review.

17.

An assignment of intrinsically disordered regions of proteins based on NMR structures.

Ota M, Koike R, Amemiya T, Tenno T, Romero PR, Hiroaki H, Dunker AK, Fukuchi S.

J Struct Biol. 2013 Jan;181(1):29-36. doi: 10.1016/j.jsb.2012.10.017. Epub 2012 Nov 7.

18.

Intrinsic protein flexibility in regulation of cell proliferation: advantages for signaling and opportunities for novel therapeutics.

Follis AV, Galea CA, Kriwacki RW.

Adv Exp Med Biol. 2012;725:27-49. doi: 10.1007/978-1-4614-0659-4_3. Review.

PMID:
22399317
19.

Intrinsic disorder in proteins associated with neurodegenerative diseases.

Uversky VN.

Front Biosci (Landmark Ed). 2009 Jun 1;14:5188-238. Review.

PMID:
19482612
20.

Intrinsic disorder-based protein interactions and their modulators.

Uversky VN.

Curr Pharm Des. 2013;19(23):4191-213. Review.

PMID:
23170892
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