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Degradation of RIG-I following cytomegalovirus infection is independent of apoptosis.

Scott I.

Microbes Infect. 2009 Oct;11(12):973-9. doi: 10.1016/j.micinf.2009.07.001. Epub 2009 Jul 8.


Lymphocytic Choriomeningitis Virus Differentially Affects the Virus-Induced Type I Interferon Response and Mitochondrial Apoptosis Mediated by RIG-I/MAVS.

Pythoud C, Rothenberger S, Martínez-Sobrido L, de la Torre JC, Kunz S.

J Virol. 2015 Jun;89(12):6240-50. doi: 10.1128/JVI.00610-15. Epub 2015 Apr 1.


MAVS-mediated host cell defense is inhibited by Borna disease virus.

Li Y, Song W, Wu J, Zhang Q, He J, Li A, Qian J, Zhai A, Hu Y, Kao W, Wei L, Zhang F, Xu D.

Int J Biochem Cell Biol. 2013 Aug;45(8):1546-55. doi: 10.1016/j.biocel.2013.05.012. Epub 2013 May 20.


Peroxisomes are platforms for cytomegalovirus' evasion from the cellular immune response.

Magalhães AC, Ferreira AR, Gomes S, Vieira M, Gouveia A, Valença I, Islinger M, Nascimento R, Schrader M, Kagan JC, Ribeiro D.

Sci Rep. 2016 May 16;6:26028. doi: 10.1038/srep26028.


DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation.

Oshiumi H, Miyashita M, Okamoto M, Morioka Y, Okabe M, Matsumoto M, Seya T.

Cell Rep. 2015 May 26;11(8):1193-207. doi: 10.1016/j.celrep.2015.04.047. Epub 2015 May 14.


UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS.

Wang P, Yang L, Cheng G, Yang G, Xu Z, You F, Sun Q, Lin R, Fikrig E, Sutton RE.

Cell Rep. 2013 Apr 25;3(4):1057-70. doi: 10.1016/j.celrep.2013.02.027. Epub 2013 Mar 28.


MDA5 plays a critical role in interferon response during hepatitis C virus infection.

Cao X, Ding Q, Lu J, Tao W, Huang B, Zhao Y, Niu J, Liu YJ, Zhong J.

J Hepatol. 2015 Apr;62(4):771-8. doi: 10.1016/j.jhep.2014.11.007. Epub 2014 Nov 21.


DDX3 directly regulates TRAF3 ubiquitination and acts as a scaffold to co-ordinate assembly of signalling complexes downstream from MAVS.

Gu L, Fullam A, McCormack N, Höhn Y, Schröder M.

Biochem J. 2017 Feb 15;474(4):571-587. doi: 10.1042/BCJ20160956. Epub 2016 Dec 15.


Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression.

Soucy-Faulkner A, Mukawera E, Fink K, Martel A, Jouan L, Nzengue Y, Lamarre D, Vande Velde C, Grandvaux N.

PLoS Pathog. 2010 Jun 3;6(6):e1000930. doi: 10.1371/journal.ppat.1000930.


An important role for mitochondrial antiviral signaling protein in the Kaposi's sarcoma-associated herpesvirus life cycle.

West JA, Wicks M, Gregory SM, Chugh P, Jacobs SR, Zhang Z, Host KM, Dittmer DP, Damania B.

J Virol. 2014 May;88(10):5778-87. doi: 10.1128/JVI.03226-13. Epub 2014 Mar 12.


Human respiratory syncytial virus nucleoprotein and inclusion bodies antagonize the innate immune response mediated by MDA5 and MAVS.

Lifland AW, Jung J, Alonas E, Zurla C, Crowe JE Jr, Santangelo PJ.

J Virol. 2012 Aug;86(15):8245-58. doi: 10.1128/JVI.00215-12. Epub 2012 May 23.


How RIG-I like receptors activate MAVS.

Wu B, Hur S.

Curr Opin Virol. 2015 Jun;12:91-8. doi: 10.1016/j.coviro.2015.04.004. Epub 2015 May 13. Review.


Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways.

Melchjorsen J, Rintahaka J, Søby S, Horan KA, Poltajainen A, Østergaard L, Paludan SR, Matikainen S.

J Virol. 2010 Nov;84(21):11350-8. doi: 10.1128/JVI.01106-10. Epub 2010 Aug 25.


Innate immunity: squelching anti-viral signalling with NLRX1.

O'Neill LA.

Curr Biol. 2008 Apr 8;18(7):R302-4. doi: 10.1016/j.cub.2008.02.021.


Human cytomegalovirus inhibits apoptosis by proteasome-mediated degradation of Bax at endoplasmic reticulum-mitochondrion contacts.

Zhang A, Hildreth RL, Colberg-Poley AM.

J Virol. 2013 May;87(10):5657-68. doi: 10.1128/JVI.00145-13. Epub 2013 Mar 13.


Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.

Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, Hannesschläger N, Schlee M, Rothenfusser S, Barchet W, Kato H, Akira S, Inoue S, Endres S, Peschel C, Hartmann G, Hornung V, Ruland J.

Nat Immunol. 2010 Jan;11(1):63-9. doi: 10.1038/ni.1824. Epub 2009 Nov 15. Erratum in: Nat Immunol. 2014 Jan;15(1):109.


Both STING and MAVS fish orthologs contribute to the induction of interferon mediated by RIG-I.

Biacchesi S, Mérour E, Lamoureux A, Bernard J, Brémont M.

PLoS One. 2012;7(10):e47737. doi: 10.1371/journal.pone.0047737. Epub 2012 Oct 16.


RIG-I mediates nonsegmented negative-sense RNA virus-induced inflammatory immune responses of primary human astrocytes.

Furr SR, Moerdyk-Schauwecker M, Grdzelishvili VZ, Marriott I.

Glia. 2010 Oct;58(13):1620-9. doi: 10.1002/glia.21034.


Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity.

Loo YM, Fornek J, Crochet N, Bajwa G, Perwitasari O, Martinez-Sobrido L, Akira S, Gill MA, García-Sastre A, Katze MG, Gale M Jr.

J Virol. 2008 Jan;82(1):335-45. Epub 2007 Oct 17.


Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling.

Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, Gao Q, Debatin KM, Beltinger C, Wei J.

J Virol. 2014 May;88(9):5152-64. doi: 10.1128/JVI.03851-13. Epub 2014 Feb 26.

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