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Inhibition of intracellular growth of Salmonella enterica serovar Typhimurium in tissue culture by antisense peptide-phosphorodiamidate morpholino oligomer.

Mitev GM, Mellbye BL, Iversen PL, Geller BL.

Antimicrob Agents Chemother. 2009 Sep;53(9):3700-4. doi: 10.1128/AAC.00099-09. Epub 2009 Jul 6.


Cationic phosphorodiamidate morpholino oligomers efficiently prevent growth of Escherichia coli in vitro and in vivo.

Mellbye BL, Weller DD, Hassinger JN, Reeves MD, Lovejoy CE, Iversen PL, Geller BL.

J Antimicrob Chemother. 2010 Jan;65(1):98-106. doi: 10.1093/jac/dkp392.


Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo.

Mellbye BL, Puckett SE, Tilley LD, Iversen PL, Geller BL.

Antimicrob Agents Chemother. 2009 Feb;53(2):525-30. doi: 10.1128/AAC.00917-08. Epub 2008 Nov 17.


Antisense peptide-phosphorodiamidate morpholino oligomer conjugate: dose-response in mice infected with Escherichia coli.

Tilley LD, Mellbye BL, Puckett SE, Iversen PL, Geller BL.

J Antimicrob Chemother. 2007 Jan;59(1):66-73. Epub 2006 Oct 31.


Antisense phosphorodiamidate morpholino oligomers targeted to an essential gene inhibit Burkholderia cepacia complex.

Greenberg DE, Marshall-Batty KR, Brinster LR, Zarember KA, Shaw PA, Mellbye BL, Iversen PL, Holland SM, Geller BL.

J Infect Dis. 2010 Jun 15;201(12):1822-30. doi: 10.1086/652807.


Antisense phosphorodiamidate morpholino oligomer inhibits viability of Escherichia coli in pure culture and in mouse peritonitis.

Geller BL, Deere J, Tilley L, Iversen PL.

J Antimicrob Chemother. 2005 Jun;55(6):983-8. Epub 2005 May 4.


Gene-silencing antisense oligomers inhibit acinetobacter growth in vitro and in vivo.

Geller BL, Marshall-Batty K, Schnell FJ, McKnight MM, Iversen PL, Greenberg DE.

J Infect Dis. 2013 Nov 15;208(10):1553-60. doi: 10.1093/infdis/jit460. Epub 2013 Oct 14.


In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virus.

Deas TS, Bennett CJ, Jones SA, Tilgner M, Ren P, Behr MJ, Stein DA, Iversen PL, Kramer LD, Bernard KA, Shi PY.

Antimicrob Agents Chemother. 2007 Jul;51(7):2470-82. Epub 2007 May 7.


Bacterial resistance to antisense peptide phosphorodiamidate morpholino oligomers.

Puckett SE, Reese KA, Mitev GM, Mullen V, Johnson RC, Pomraning KR, Mellbye BL, Tilley LD, Iversen PL, Freitag M, Geller BL.

Antimicrob Agents Chemother. 2012 Dec;56(12):6147-53. doi: 10.1128/AAC.00850-12. Epub 2012 Sep 17.


Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers.

Howard JJ, Sturge CR, Moustafa DA, Daly SM, Marshall-Batty KR, Felder CF, Zamora D, Yabe-Gill M, Labandeira-Rey M, Bailey SM, Wong M, Goldberg JB, Geller BL, Greenberg DE.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e01938-16. doi: 10.1128/AAC.01938-16. Print 2017 Apr.


Peptide conjugated phosphorodiamidate morpholino oligomers increase survival of mice challenged with Ames Bacillus anthracis.

Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S.

Nucleic Acid Ther. 2012 Oct;22(5):316-22. doi: 10.1089/nat.2012.0362. Epub 2012 Sep 14.


Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers.

Geller BL, Deere JD, Stein DA, Kroeker AD, Moulton HM, Iversen PL.

Antimicrob Agents Chemother. 2003 Oct;47(10):3233-9.


Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site.

Yuan J, Stein DA, Lim T, Qiu D, Coughlin S, Liu Z, Wang Y, Blouch R, Moulton HM, Iversen PL, Yang D.

J Virol. 2006 Dec;80(23):11510-9. Epub 2006 Sep 20.


Eradication of intracellular Salmonella enterica serovar Typhimurium with a small-molecule, host cell-directed agent.

Chiu HC, Kulp SK, Soni S, Wang D, Gunn JS, Schlesinger LS, Chen CS.

Antimicrob Agents Chemother. 2009 Dec;53(12):5236-44. doi: 10.1128/AAC.00555-09. Epub 2009 Oct 5.


Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus.

Stein DA, Huang CY, Silengo S, Amantana A, Crumley S, Blouch RE, Iversen PL, Kinney RM.

J Antimicrob Chemother. 2008 Sep;62(3):555-65. doi: 10.1093/jac/dkn221. Epub 2008 Jun 19.


Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers.

Stein DA.

Curr Pharm Des. 2008;14(25):2619-34. Review.


Salicylate reduces the antimicrobial activity of ciprofloxacin against extracellular Salmonella enterica serovar Typhimurium, but not against Salmonella in macrophages.

Hartog E, Menashe O, Kler E, Yaron S.

J Antimicrob Chemother. 2010 May;65(5):888-96. doi: 10.1093/jac/dkq077. Epub 2010 Mar 17.


A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus.

Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R.

Antimicrob Agents Chemother. 2008 Jun;52(6):1970-81. doi: 10.1128/AAC.00011-08. Epub 2008 Mar 17.

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