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Items: 1 to 20 of 77

1.

Receptor density is key to the alpha2/beta interferon differential activities.

Moraga I, Harari D, Schreiber G, Uzé G, Pellegrini S.

Mol Cell Biol. 2009 Sep;29(17):4778-87. doi: 10.1128/MCB.01808-08. Epub 2009 Jun 29.

2.

Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.

Marijanovic Z, Ragimbeau J, van der Heyden J, Uzé G, Pellegrini S.

Biochem J. 2007 Oct 1;407(1):141-51.

3.
4.

An interferon alpha2 mutant optimized by phage display for IFNAR1 binding confers specifically enhanced antitumor activities.

Kalie E, Jaitin DA, Abramovich R, Schreiber G.

J Biol Chem. 2007 Apr 13;282(15):11602-11. Epub 2007 Feb 19.

5.

Differences in activity between alpha and beta type I interferons explored by mutational analysis.

Runkel L, Pfeffer L, Lewerenz M, Monneron D, Yang CH, Murti A, Pellegrini S, Goelz S, Uzé G, Mogensen K.

J Biol Chem. 1998 Apr 3;273(14):8003-8.

6.

Defective Jak-Stat activation in renal cell carcinoma is associated with interferon-alpha resistance.

Shang D, Liu Y, Ito N, Kamoto T, Ogawa O.

Cancer Sci. 2007 Aug;98(8):1259-64. Epub 2007 Jun 15.

7.

Virus Multiplicity of Infection Affects Type I Interferon Subtype Induction Profiles and Interferon-Stimulated Genes.

Zaritsky LA, Bedsaul JR, Zoon KC.

J Virol. 2015 Nov;89(22):11534-48. doi: 10.1128/JVI.01727-15. Epub 2015 Sep 9.

9.

Interferon-β induces apoptosis in human SH-SY5Y neuroblastoma cells through activation of JAK-STAT signaling and down-regulation of PI3K/Akt pathway.

Dedoni S, Olianas MC, Onali P.

J Neurochem. 2010 Dec;115(6):1421-33. doi: 10.1111/j.1471-4159.2010.07046.x. Epub 2010 Nov 11.

10.
11.

Inquiring into the differential action of interferons (IFNs): an IFN-alpha2 mutant with enhanced affinity to IFNAR1 is functionally similar to IFN-beta.

Jaitin DA, Roisman LC, Jaks E, Gavutis M, Piehler J, Van der Heyden J, Uze G, Schreiber G.

Mol Cell Biol. 2006 Mar;26(5):1888-97.

12.

Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha.

Rani MR, Foster GR, Leung S, Leaman D, Stark GR, Ransohoff RM.

J Biol Chem. 1996 Sep 13;271(37):22878-84.

13.

Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell.

Ho LJ, Hung LF, Weng CY, Wu WL, Chou P, Lin YL, Chang DM, Tai TY, Lai JH.

J Immunol. 2005 Jun 15;174(12):8163-72.

14.

Differential recognition of the type I interferon receptor by interferons tau and alpha is responsible for their disparate cytotoxicities.

Subramaniam PS, Khan SA, Pontzer CH, Johnson HM.

Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12270-4.

15.

Role of interferon alpha/beta receptor chain 1 in the structure and transmembrane signaling of the interferon alpha/beta receptor complex.

Constantinescu SN, Croze E, Wang C, Murti A, Basu L, Mullersman JE, Pfeffer LM.

Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9602-6.

16.

Temporal and spatial resolution of type I and III interferon responses in vivo.

Pulverer JE, Rand U, Lienenklaus S, Kugel D, Zietara N, Kochs G, Naumann R, Weiss S, Staeheli P, Hauser H, Köster M.

J Virol. 2010 Sep;84(17):8626-38. doi: 10.1128/JVI.00303-10. Epub 2010 Jun 23.

17.

Mutation of the IFNAR-1 receptor binding site of human IFN-alpha2 generates type I IFN competitive antagonists.

Pan M, Kalie E, Scaglione BJ, Raveche ES, Schreiber G, Langer JA.

Biochemistry. 2008 Nov 18;47(46):12018-27. doi: 10.1021/bi801588g. Epub 2008 Oct 21.

PMID:
18937499
18.

Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster.

Lutfalla G, Holland SJ, Cinato E, Monneron D, Reboul J, Rogers NC, Smith JM, Stark GR, Gardiner K, Mogensen KE, et al.

EMBO J. 1995 Oct 16;14(20):5100-8.

19.

Role of IFN-alpha/beta signaling in the prevention of genital herpes virus type 2 infection.

Svensson A, Bellner L, Magnusson M, Eriksson K.

J Reprod Immunol. 2007 Jun;74(1-2):114-23. Epub 2006 Nov 7.

PMID:
17092567
20.

Differential use of the betaL subunit of the type I interferon (IFN) receptor determines signaling specificity for IFNalpha2 and IFNbeta.

Domanski P, Nadeau OW, Platanias LC, Fish E, Kellum M, Pitha P, Colamonici OR.

J Biol Chem. 1998 Feb 6;273(6):3144-7.

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