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Items: 1 to 20 of 99

1.

Essential function for the GTPase TC21 in homeostatic antigen receptor signaling.

Delgado P, Cubelos B, Calleja E, Martínez-Martín N, Ciprés A, Mérida I, Bellas C, Bustelo XR, Alarcón B.

Nat Immunol. 2009 Aug;10(8):880-8. doi: 10.1038/ni.1749. Epub 2009 Jun 28.

PMID:
19561613
2.

T cell receptor internalization from the immunological synapse is mediated by TC21 and RhoG GTPase-dependent phagocytosis.

Martínez-Martín N, Fernández-Arenas E, Cemerski S, Delgado P, Turner M, Heuser J, Irvine DJ, Huang B, Bustelo XR, Shaw A, Alarcón B.

Immunity. 2011 Aug 26;35(2):208-22. doi: 10.1016/j.immuni.2011.06.003. Epub 2011 Aug 4.

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Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation.

Murphy GA, Graham SM, Morita S, Reks SE, Rogers-Graham K, Vojtek A, Kelley GG, Der CJ.

J Biol Chem. 2002 Mar 22;277(12):9966-75. Epub 2002 Jan 11.

6.

Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice.

Okkenhaug K, Bilancio A, Farjot G, Priddle H, Sancho S, Peskett E, Pearce W, Meek SE, Salpekar A, Waterfield MD, Smith AJ, Vanhaesebroeck B.

Science. 2002 Aug 9;297(5583):1031-4. Epub 2002 Jul 18.

7.

Signaling pathways regulating TC21-induced tumorigenesis.

Erdogan M, Pozzi A, Bhowmick N, Moses HL, Zent R.

J Biol Chem. 2007 Sep 21;282(38):27713-20. Epub 2007 Jul 26.

8.

RRas2, RhoG and T-cell phagocytosis.

Alarcón B, Martínez-Martín N.

Small GTPases. 2012 Apr-Jun;3(2):97-101. doi: 10.4161/sgtp.19138.

9.

TC21 causes transformation by Raf-independent signaling pathways.

Graham SM, Vojtek AB, Huff SY, Cox AD, Clark GJ, Cooper JA, Der CJ.

Mol Cell Biol. 1996 Nov;16(11):6132-40.

10.

A negative role for phosphoinositide 3-kinase in T-cell antigen receptor function.

Reif K, Lucas S, Cantrell D.

Curr Biol. 1997 May 1;7(5):285-93.

14.

B cell receptor signaling: picky about PI3Ks.

Limon JJ, Fruman DA.

Sci Signal. 2010 Aug 10;3(134):pe25. doi: 10.1126/scisignal.3134pe25. Review.

PMID:
20699473
15.

T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes.

Raab M, Wang H, Lu Y, Smith X, Wu Z, Strebhardt K, Ladbury JE, Rudd CE.

Immunity. 2010 Apr 23;32(4):541-56. doi: 10.1016/j.immuni.2010.03.007. Epub 2010 Mar 25.

16.

Phosphoinositide 3-kinase regulation of T cell receptor-mediated interleukin-2 gene expression in normal T cells.

Eder AM, Dominguez L, Franke TF, Ashwell JD.

J Biol Chem. 1998 Oct 23;273(43):28025-31.

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The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction.

Wu J, Zhao Q, Kurosaki T, Weiss A.

J Exp Med. 1997 May 19;185(10):1877-82.

20.

BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells.

Banerji L, Glassford J, Lea NC, Thomas NS, Klaus GG, Lam EW.

Oncogene. 2001 Nov 1;20(50):7352-67.

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