Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 60

1.

Synthesis and evaluation of new endomorphin analogues modified at the Pro(2) residue.

Torino D, Mollica A, Pinnen F, Lucente G, Feliciani F, Davis P, Lai J, Ma SW, Porreca F, Hruby VJ.

Bioorg Med Chem Lett. 2009 Aug 1;19(15):4115-8. doi: 10.1016/j.bmcl.2009.06.008. Epub 2009 Jun 6.

2.
3.

Synthesis and evaluation of new endomorphin-2 analogues containing (Z)-alpha,beta-didehydrophenylalanine (Delta(Z)Phe) residues.

Torino D, Mollica A, Pinnen F, Feliciani F, Lucente G, Fabrizi G, Portalone G, Davis P, Lai J, Ma SW, Porreca F, Hruby VJ.

J Med Chem. 2010 Jun 10;53(11):4550-4. doi: 10.1021/jm1001343.

4.
5.

Antinociceptive and antidepressant-like action of endomorphin-2 analogs with proline surrogates in position 2.

Perlikowska R, Piekielna J, Mazur M, Koralewski R, Olczak J, do Rego JC, Fichna J, Modranka J, Janecki T, Janecka A.

Bioorg Med Chem. 2014 Sep 1;22(17):4803-9. doi: 10.1016/j.bmc.2014.06.056. Epub 2014 Jul 9.

PMID:
25047937
6.

Synthesis and biological activity of endomorphin-2 analogs incorporating piperidine-2-, 3- or 4-carboxylic acids instead of proline in position 2.

Staniszewska R, Fichna J, Gach K, Toth G, Poels J, Vanden Broeck J, Janecka A.

Chem Biol Drug Des. 2008 Jul;72(1):91-4. doi: 10.1111/j.1747-0285.2008.00678.x. Epub 2008 Jun 13.

PMID:
18564215
7.

Endomorphin-1 analogues containing beta-proline are mu-opioid receptor agonists and display enhanced enzymatic hydrolysis resistance.

Cardillo G, Gentilucci L, Qasem AR, Sgarzi F, Spampinato S.

J Med Chem. 2002 Jun 6;45(12):2571-8.

PMID:
12036366
8.

Biological activity of endomorphin and [Dmt1]endomorphin analogs with six-membered proline surrogates in position 2.

Perlikowska R, Gach K, Fichna J, Toth G, Walkowiak B, do-Rego JC, Janecka A.

Bioorg Med Chem. 2009 Jun 1;17(11):3789-94. doi: 10.1016/j.bmc.2009.04.046. Epub 2009 May 3.

PMID:
19435668
9.
10.

Design and synthesis of 1-aminocycloalkane-1-carboxylic acid-substituted deltorphin analogues: unique delta and mu opioid activity in modified peptides.

Breveglieri A, Guerrini R, Salvadori S, Bianchi C, Bryant SD, Attila M, Lazarus LH.

J Med Chem. 1996 Feb 2;39(3):773-80.

PMID:
8576920
11.

Pharmacology of a new tritiated endomorphin-2 analog containing the proline mimetic cis-2-aminocyclohexanecarboxylic acid.

Keresztes A, Birkás E, Páhi A, Tóth G, Bakota L, Gulya K, Szücs M.

Peptides. 2011 Apr;32(4):722-8. doi: 10.1016/j.peptides.2011.01.017. Epub 2011 Jan 22.

PMID:
21262295
12.

Design, synthesis and pharmacological characterization of endomorphin analogues with non-cyclic amino acid residues in position 2.

Perlikowska R, Fichna J, Wyrebska A, Poels J, Vanden Broeck J, Toth G, Storr M, do Rego JC, Janecka A.

Basic Clin Pharmacol Toxicol. 2010 Feb;106(2):106-13. doi: 10.1111/j.1742-7843.2009.00476.x. Epub 2009 Oct 28.

13.

Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration.

Liu X, Zhao L, Wang Y, Mou L, Yang J, Zhang Y, Wang D, Wang R.

Bioorg Med Chem Lett. 2015 Nov 15;25(22):5393-7. doi: 10.1016/j.bmcl.2015.09.025. Epub 2015 Sep 11.

PMID:
26403932
15.

Misincorporation of the proline homologue Aze (azetidine-2-carboxylic acid) into recombinant myelin basic protein.

Bessonov K, Bamm VV, Harauz G.

Phytochemistry. 2010 Apr;71(5-6):502-7. doi: 10.1016/j.phytochem.2009.12.010. Epub 2010 Jan 11.

PMID:
20064647
16.

Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2).

Fichna J, do-Rego JC, Chung NN, Lemieux C, Schiller PW, Poels J, Broeck JV, Costentin J, Janecka A.

J Med Chem. 2007 Feb 8;50(3):512-20.

PMID:
17266203
17.

The effect of Pro(2) modifications on the structural and pharmacological properties of endomorphin-2.

Borics A, Mallareddy JR, Timári I, Kövér KE, Keresztes A, Tóth G.

J Med Chem. 2012 Oct 11;55(19):8418-28. doi: 10.1021/jm300836n. Epub 2012 Sep 20.

PMID:
22957923
18.
19.

Stability against enzymatic hydrolysis of endomorphin-1 analogues containing beta-proline.

Cardillo G, Gentilucci L, Tolomelli A, Calienni M, Qasem AR, Spampinato S.

Org Biomol Chem. 2003 May 7;1(9):1498-502.

PMID:
12926278
20.

Supplemental Content

Support Center