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Items: 1 to 20 of 400

1.

Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.

Doherty GA, Byrne SM, Molloy ES, Malhotra V, Austin SC, Kay EW, Murray FE, Fitzgerald DJ.

BMC Cancer. 2009 Jun 26;9:207. doi: 10.1186/1471-2407-9-207.

2.

Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells.

Timoshenko AV, Xu G, Chakrabarti S, Lala PK, Chakraborty C.

Exp Cell Res. 2003 Oct 1;289(2):265-74.

PMID:
14499627
3.

PGE2-induced hypertrophy of cardiac myocytes involves EP4 receptor-dependent activation of p42/44 MAPK and EGFR transactivation.

Mendez M, LaPointe MC.

Am J Physiol Heart Circ Physiol. 2005 May;288(5):H2111-7. Epub 2004 Dec 30.

4.

Human papillomavirus E5 protein induces expression of the EP4 subtype of prostaglandin E2 receptor in cyclic AMP response element-dependent pathways in cervical cancer cells.

Oh JM, Kim SH, Lee YI, Seo M, Kim SY, Song YS, Kim WH, Juhnn YS.

Carcinogenesis. 2009 Jan;30(1):141-9. doi: 10.1093/carcin/bgn236. Epub 2008 Oct 9.

PMID:
18849297
5.

Activation of epidermal growth factor receptor signaling by the prostaglandin E(2) receptor EP4 pathway during gastric tumorigenesis.

Oshima H, Popivanova BK, Oguma K, Kong D, Ishikawa TO, Oshima M.

Cancer Sci. 2011 Apr;102(4):713-9. doi: 10.1111/j.1349-7006.2011.01847.x. Epub 2011 Feb 2.

6.

Molecular and pharmacological blockade of the EP4 receptor selectively inhibits both proliferation and invasion of human inflammatory breast cancer cells.

Robertson FM, Simeone AM, Mazumdar A, Shah AH, McMurray JS, Ghosh S, Cristofanilli M.

J Exp Ther Oncol. 2008;7(4):299-312.

PMID:
19227010
7.

Epidermal growth factor receptor-mediated proliferation of enterocytes requires p21waf1/cip1 expression.

Sheng G, Bernabe KQ, Guo J, Warner BW.

Gastroenterology. 2006 Jul;131(1):153-64.

PMID:
16831599
8.

Endothelin-1-induced prostaglandin E2-EP2, EP4 signaling regulates vascular endothelial growth factor production and ovarian carcinoma cell invasion.

Spinella F, Rosanò L, Di Castro V, Natali PG, Bagnato A.

J Biol Chem. 2004 Nov 5;279(45):46700-5. Epub 2004 Sep 3.

10.

Inhibition of COX-2 with NS-398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: possibilities for combination therapy.

Banu N, Buda A, Chell S, Elder D, Moorghen M, Paraskeva C, Qualtrough D, Pignatelli M.

Cell Prolif. 2007 Oct;40(5):768-79.

PMID:
17877615
11.

The role of cyclooxygenase-2 in mediating the effects of histamine on cell proliferation and vascular endothelial growth factor production in colorectal cancer.

Cianchi F, Cortesini C, Schiavone N, Perna F, Magnelli L, Fanti E, Bani D, Messerini L, Fabbroni V, Perigli G, Capaccioli S, Masini E.

Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6807-15.

12.

Cyclooxygenase-2 expression is dependent upon epidermal growth factor receptor expression or activation in androgen independent prostate cancer.

Jia RP, Xu LW, Su Q, Zhao JH, Li WC, Wang F, Xu Z.

Asian J Androl. 2008 Sep;10(5):758-64. doi: 10.1111/j.1745-7262.2008.00423.x.

13.

Role of cAMP in the promotion of colorectal cancer cell growth by prostaglandin E2.

Löffler I, Grün M, Böhmer FD, Rubio I.

BMC Cancer. 2008 Dec 19;8:380. doi: 10.1186/1471-2407-8-380.

15.

EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures.

Minamizaki T, Yoshiko Y, Kozai K, Aubin JE, Maeda N.

Bone. 2009 Jun;44(6):1177-85. doi: 10.1016/j.bone.2009.02.010. Epub 2009 Feb 21.

PMID:
19233324
16.

Lipopolysaccharide stimulates the production of prostaglandin E2 and the receptor Ep4 in osteoblasts.

Shoji M, Tanabe N, Mitsui N, Tanaka H, Suzuki N, Takeichi O, Sugaya A, Maeno M.

Life Sci. 2006 Mar 20;78(17):2012-8. Epub 2005 Nov 14.

PMID:
16289620
17.

EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells.

Shimizu M, Deguchi A, Joe AK, Mckoy JF, Moriwaki H, Weinstein IB.

J Exp Ther Oncol. 2005;5(1):69-78.

PMID:
16416603
18.

EP4 upregulation of Ras signaling and feedback regulation of Ras in human colon tissues and cancer cells.

Wu CH, Shih YW, Chang CH, Ou TT, Huang CC, Hsu JD, Wang CJ.

Arch Toxicol. 2010 Sep;84(9):731-40. doi: 10.1007/s00204-010-0562-4. Epub 2010 Jun 23.

PMID:
20571779
19.

Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer.

Doherty GA, Byrne SM, Austin SC, Scully GM, Sadlier DM, Neilan TG, Kay EW, Murray FE, Fitzgerald DJ.

Br J Cancer. 2009 Aug 4;101(3):483-91. doi: 10.1038/sj.bjc.6605144.

20.

Induction of cyclooxygenase-2 expression by prostaglandin E2 stimulation of the prostanoid EP4 receptor via coupling to Gαi and transactivation of the epidermal growth factor receptor in HCA-7 human colon cancer cells.

Yoshida K, Fujino H, Otake S, Seira N, Regan JW, Murayama T.

Eur J Pharmacol. 2013 Oct 15;718(1-3):408-17. doi: 10.1016/j.ejphar.2013.08.002. Epub 2013 Aug 22.

PMID:
23973650

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