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Items: 1 to 20 of 144

1.

Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery.

Chang TH, Kubota T, Matsuoka M, Jones S, Bradfute SB, Bray M, Ozato K.

PLoS Pathog. 2009 Jun;5(6):e1000493. doi: 10.1371/journal.ppat.1000493. Epub 2009 Jun 26.

2.

Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells.

Leung LW, Park MS, Martinez O, Valmas C, López CB, Basler CF.

Immunol Cell Biol. 2011 Oct;89(7):792-802. doi: 10.1038/icb.2010.169. Epub 2011 Jan 25.

3.

Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation.

Yen B, Mulder LC, Martinez O, Basler CF.

J Virol. 2014 Nov;88(21):12500-10. doi: 10.1128/JVI.02163-14. Epub 2014 Aug 20.

4.

DRBP76 associates with Ebola virus VP35 and suppresses viral polymerase function.

Shabman RS, Leung DW, Johnson J, Glennon N, Gulcicek EE, Stone KL, Leung L, Hensley L, Amarasinghe GK, Basler CF.

J Infect Dis. 2011 Nov;204 Suppl 3:S911-8. doi: 10.1093/infdis/jir343.

5.

The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide.

Jin H, Yan Z, Prabhakar BS, Feng Z, Ma Y, Verpooten D, Ganesh B, He B.

J Gen Virol. 2010 Feb;91(Pt 2):352-61. doi: 10.1099/vir.0.017343-0. Epub 2009 Oct 14.

6.

Effects of Filovirus Interferon Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA Virus Infection.

Yen BC, Basler CF.

J Virol. 2016 Apr 29;90(10):5108-5118. doi: 10.1128/JVI.00191-16. Print 2016 May 15.

7.

Evasion of interferon responses by Ebola and Marburg viruses.

Basler CF, Amarasinghe GK.

J Interferon Cytokine Res. 2009 Sep;29(9):511-20. doi: 10.1089/jir.2009.0076. Review.

8.

Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells.

Feagins AR, Basler CF.

Virology. 2015 Nov;485:145-52. doi: 10.1016/j.virol.2015.07.010. Epub 2015 Aug 6.

9.

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication.

Bharaj P, Atkins C, Luthra P, Giraldo MI, Dawes BE, Miorin L, Johnson JR, Krogan NJ, Basler CF, Freiberg AN, Rajsbaum R.

J Virol. 2017 Aug 24;91(18). pii: e00833-17. doi: 10.1128/JVI.00833-17. Print 2017 Sep 15.

10.

The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

Basler CF, Mikulasova A, Martinez-Sobrido L, Paragas J, Mühlberger E, Bray M, Klenk HD, Palese P, García-Sastre A.

J Virol. 2003 Jul;77(14):7945-56.

11.

PIAS1 negatively modulates virus triggered type I IFN signaling by blocking the DNA binding activity of IRF3.

Li R, Pan Y, Shi DD, Zhang Y, Zhang J.

Antiviral Res. 2013 Nov;100(2):546-54. doi: 10.1016/j.antiviral.2013.09.001. Epub 2013 Sep 12.

PMID:
24036127
12.

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins.

Edwards MR, Liu G, Mire CE, Sureshchandra S, Luthra P, Yen B, Shabman RS, Leung DW, Messaoudi I, Geisbert TW, Amarasinghe GK, Basler CF.

Cell Rep. 2016 Feb 23;14(7):1632-1640. doi: 10.1016/j.celrep.2016.01.049. Epub 2016 Feb 11.

14.

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling.

Cárdenas WB, Loo YM, Gale M Jr, Hartman AL, Kimberlin CR, Martínez-Sobrido L, Saphire EO, Basler CF.

J Virol. 2006 Jun;80(11):5168-78.

15.

Mutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs.

Prins KC, Delpeut S, Leung DW, Reynard O, Volchkova VA, Reid SP, Ramanan P, Cárdenas WB, Amarasinghe GK, Volchkov VE, Basler CF.

J Virol. 2010 Mar;84(6):3004-15. doi: 10.1128/JVI.02459-09. Epub 2010 Jan 13.

16.
17.

Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells.

Osterlund P, Veckman V, Sirén J, Klucher KM, Hiscott J, Matikainen S, Julkunen I.

J Virol. 2005 Aug;79(15):9608-17.

18.

Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.

Heo KS, Chang E, Takei Y, Le NT, Woo CH, Sullivan MA, Morrell C, Fujiwara K, Abe J.

Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):321-9. doi: 10.1161/ATVBAHA.112.300619. Epub 2012 Nov 29.

19.
20.

Ebola virus-like particles stimulate type I interferons and proinflammatory cytokine expression through the toll-like receptor and interferon signaling pathways.

Ayithan N, Bradfute SB, Anthony SM, Stuthman KS, Dye JM, Bavari S, Bray M, Ozato K.

J Interferon Cytokine Res. 2014 Feb;34(2):79-89. doi: 10.1089/jir.2013.0035. Epub 2013 Oct 8.

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