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Items: 1 to 20 of 254

1.

Cyclophilin D gene ablation protects mice from ischemic renal injury.

Devalaraja-Narashimha K, Diener AM, Padanilam BJ.

Am J Physiol Renal Physiol. 2009 Sep;297(3):F749-59. doi: 10.1152/ajprenal.00239.2009. Epub 2009 Jun 24.

2.

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.

Schinzel AC, Takeuchi O, Huang Z, Fisher JK, Zhou Z, Rubens J, Hetz C, Danial NN, Moskowitz MA, Korsmeyer SJ.

Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12005-10. Epub 2005 Aug 15.

3.

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.

Nakagawa T, Shimizu S, Watanabe T, Yamaguchi O, Otsu K, Yamagata H, Inohara H, Kubo T, Tsujimoto Y.

Nature. 2005 Mar 31;434(7033):652-8.

PMID:
15800626
4.

Pharmacologic targeting or genetic deletion of mitochondrial cyclophilin D protects from NSAID-induced small intestinal ulceration in mice.

LoGuidice A, Ramirez-Alcantara V, Proli A, Gavillet B, Boelsterli UA.

Toxicol Sci. 2010 Nov;118(1):276-85. doi: 10.1093/toxsci/kfq226. Epub 2010 Jul 28.

5.

PERP, a p53 proapoptotic target, mediates apoptotic cell death in renal ischemia.

Singaravelu K, Devalaraja-Narashimha K, Lastovica B, Padanilam BJ.

Am J Physiol Renal Physiol. 2009 Apr;296(4):F847-58. doi: 10.1152/ajprenal.90438.2008. Epub 2009 Jan 21.

6.

Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioning.

Hausenloy DJ, Lim SY, Ong SG, Davidson SM, Yellon DM.

Cardiovasc Res. 2010 Oct 1;88(1):67-74. doi: 10.1093/cvr/cvq113. Epub 2010 Apr 16.

7.

ROS-mediated PARP activity undermines mitochondrial function after permeability transition pore opening during myocardial ischemia-reperfusion.

Schriewer JM, Peek CB, Bass J, Schumacker PT.

J Am Heart Assoc. 2013 Apr 18;2(2):e000159. doi: 10.1161/JAHA.113.000159.

8.

Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore.

Nguyen TT, Stevens MV, Kohr M, Steenbergen C, Sack MN, Murphy E.

J Biol Chem. 2011 Nov 18;286(46):40184-92. doi: 10.1074/jbc.M111.243469. Epub 2011 Sep 19.

9.

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death.

Baines CP, Kaiser RA, Purcell NH, Blair NS, Osinska H, Hambleton MA, Brunskill EW, Sayen MR, Gottlieb RA, Dorn GW, Robbins J, Molkentin JD.

Nature. 2005 Mar 31;434(7033):658-62.

PMID:
15800627
10.

Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury.

Kim SY, Shim MS, Kim KY, Weinreb RN, Wheeler LA, Ju WK.

Cell Death Dis. 2014 Mar 6;5:e1105. doi: 10.1038/cddis.2014.80.

11.

Knockdown of Cyclophilin D Gene by RNAi Protects Rat from Ischemia/ Reperfusion-Induced Renal Injury.

Hu W, Chen Z, Ye Z, Xia D, Xia Z, Ma J, Zhu M, Chen G.

Kidney Blood Press Res. 2010;33(3):193-9. doi: 10.1159/000316704. Epub 2010 Jun 24.

12.

Mitochondrial cyclophilin-D as a potential therapeutic target for post-myocardial infarction heart failure.

Lim SY, Hausenloy DJ, Arjun S, Price AN, Davidson SM, Lythgoe MF, Yellon DM.

J Cell Mol Med. 2011 Nov;15(11):2443-51. doi: 10.1111/j.1582-4934.2010.01235.x.

13.

Loss of clusterin expression worsens renal ischemia-reperfusion injury.

Zhou W, Guan Q, Kwan CC, Chen H, Gleave ME, Nguan CY, Du C.

Am J Physiol Renal Physiol. 2010 Mar;298(3):F568-78. doi: 10.1152/ajprenal.00399.2009. Epub 2009 Dec 9.

14.

[Effect of p21 on the changes in renal tubular epithelial cells after ischemia/reperfusion injury of kidney].

Li KL, Wang JM, Ding HL, Zhao L, Song RH, Chen L.

Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005 Oct;17(10):606-10. Chinese.

15.

Synergistic protective effect of cyclosporin A and rotenone against hypoxia-reoxygenation in cardiomyocytes.

Teixeira G, Abrial M, Portier K, Chiari P, Couture-Lepetit E, Tourneur Y, Ovize M, Gharib A.

J Mol Cell Cardiol. 2013 Mar;56:55-62. doi: 10.1016/j.yjmcc.2012.11.023. Epub 2012 Dec 10.

PMID:
23238221
16.

The targeting of cyclophilin D by RNAi as a novel cardioprotective therapy: evidence from two-photon imaging.

Kato M, Akao M, Matsumoto-Ida M, Makiyama T, Iguchi M, Takeda T, Shimizu S, Kita T.

Cardiovasc Res. 2009 Jul 15;83(2):335-44. doi: 10.1093/cvr/cvp094. Epub 2009 Mar 19.

17.
18.

Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening.

Petrosillo G, Colantuono G, Moro N, Ruggiero FM, Tiravanti E, Di Venosa N, Fiore T, Paradies G.

Am J Physiol Heart Circ Physiol. 2009 Oct;297(4):H1487-93. doi: 10.1152/ajpheart.00163.2009. Epub 2009 Aug 14.

19.

Opening of mitochondrial permeability transition pore induces hypercontracture in Ca2+ overloaded cardiac myocytes.

Ruiz-Meana M, Abellán A, Miró-Casas E, Garcia-Dorado D.

Basic Res Cardiol. 2007 Nov;102(6):542-52. Epub 2007 Sep 24.

PMID:
17891523
20.

Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization.

Lin DT, Lechleiter JD.

J Biol Chem. 2002 Aug 23;277(34):31134-41. Epub 2002 Jun 19.

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