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Items: 1 to 20 of 88

1.

Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation.

Papapetrou EP, Tomishima MJ, Chambers SM, Mica Y, Reed E, Menon J, Tabar V, Mo Q, Studer L, Sadelain M.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12759-64. doi: 10.1073/pnas.0904825106. Epub 2009 Jun 23.

2.

Optimal reprogramming factor stoichiometry increases colony numbers and affects molecular characteristics of murine induced pluripotent stem cells.

Tiemann U, Sgodda M, Warlich E, Ballmaier M, Schöler HR, Schambach A, Cantz T.

Cytometry A. 2011 Jun;79(6):426-35. doi: 10.1002/cyto.a.21072. Epub 2011 May 4.

3.
4.

Residual expression of the reprogramming factors prevents differentiation of iPSC generated from human fibroblasts and cord blood CD34+ progenitors.

Ramos-Mejía V, Montes R, Bueno C, Ayllón V, Real PJ, Rodríguez R, Menendez P.

PLoS One. 2012;7(4):e35824. doi: 10.1371/journal.pone.0035824. Epub 2012 Apr 24.

5.

Induction of pluripotency: from mouse to human.

Zaehres H, Schöler HR.

Cell. 2007 Nov 30;131(5):834-5.

6.

Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors.

Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Araúzo-Bravo MJ, Ruau D, Han DW, Zenke M, Schöler HR.

Nature. 2008 Jul 31;454(7204):646-50. doi: 10.1038/nature07061. Epub 2008 Jun 29.

PMID:
18594515
7.

Klf4 interacts directly with Oct4 and Sox2 to promote reprogramming.

Wei Z, Yang Y, Zhang P, Andrianakos R, Hasegawa K, Lyu J, Chen X, Bai G, Liu C, Pera M, Lu W.

Stem Cells. 2009 Dec;27(12):2969-78. doi: 10.1002/stem.231.

8.

Endogenous KLF4 expression in human fetal endothelial cells allows for reprogramming to pluripotency with just OCT3/4 and SOX2--brief report.

Ho PJ, Yen ML, Lin JD, Chen LS, Hu HI, Yeh CK, Peng CY, Lin CY, Yet SF, Yen BL.

Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):1905-7. doi: 10.1161/ATVBAHA.110.206540. Epub 2010 Aug 5.

9.

MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells.

Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS.

Cell. 2009 May 15;137(4):647-58. doi: 10.1016/j.cell.2009.02.038. Epub 2009 Apr 30.

10.

Reprogramming of murine and human somatic cells using a single polycistronic vector.

Carey BW, Markoulaki S, Hanna J, Saha K, Gao Q, Mitalipova M, Jaenisch R.

Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):157-62. doi: 10.1073/pnas.0811426106. Epub 2008 Dec 24. Erratum in: Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5449. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11818.

11.

Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes.

Aasen T, Raya A, Barrero MJ, Garreta E, Consiglio A, Gonzalez F, Vassena R, Bilić J, Pekarik V, Tiscornia G, Edel M, Boué S, Izpisúa Belmonte JC.

Nat Biotechnol. 2008 Nov;26(11):1276-84. doi: 10.1038/nbt.1503. Epub 2008 Oct 17.

PMID:
18931654
12.

Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential.

Ohnuki M, Tanabe K, Sutou K, Teramoto I, Sawamura Y, Narita M, Nakamura M, Tokunaga Y, Nakamura M, Watanabe A, Yamanaka S, Takahashi K.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12426-31. doi: 10.1073/pnas.1413299111. Epub 2014 Aug 5.

13.

Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells.

Zhou W, Freed CR.

Stem Cells. 2009 Nov;27(11):2667-74. doi: 10.1002/stem.201.

14.

More synergetic cooperation of Yamanaka factors in induced pluripotent stem cells than in embryonic stem cells.

Huang J, Chen T, Liu X, Jiang J, Li J, Li D, Liu XS, Li W, Kang J, Pei G.

Cell Res. 2009 Oct;19(10):1127-38. doi: 10.1038/cr.2009.106. Epub 2009 Sep 8.

PMID:
19736564
15.

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.

Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, Chen S, Muhlestein W, Melton DA.

Nat Biotechnol. 2008 Nov;26(11):1269-75. doi: 10.1038/nbt.1502. Epub 2008 Oct 12.

PMID:
18849973
16.

Fibroblast-derived induced pluripotent stem cells show no common retroviral vector insertions.

Varas F, Stadtfeld M, de Andres-Aguayo L, Maherali N, di Tullio A, Pantano L, Notredame C, Hochedlinger K, Graf T.

Stem Cells. 2009 Feb;27(2):300-6. doi: 10.1634/stemcells.2008-0696.

18.

Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells.

Meissner A, Wernig M, Jaenisch R.

Nat Biotechnol. 2007 Oct;25(10):1177-81. Epub 2007 Aug 27.

PMID:
17724450
19.

Effective generation of iPS cells from CD34+ cord blood cells by inhibition of p53.

Takenaka C, Nishishita N, Takada N, Jakt LM, Kawamata S.

Exp Hematol. 2010 Feb;38(2):154-62. doi: 10.1016/j.exphem.2009.11.003. Epub 2009 Nov 14.

PMID:
19922768
20.

Generating iPS cells from MEFS through forced expression of Sox-2, Oct-4, c-Myc, and Klf4.

Welstead GG, Brambrink T, Jaenisch R.

J Vis Exp. 2008 Apr 7;(14). pii: 734. doi: 10.3791/734.

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