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Items: 1 to 20 of 74


Sod2 knockdown in the musculature has whole-organism consequences in Drosophila.

Martin I, Jones MA, Rhodenizer D, Zheng J, Warrick JM, Seroude L, Grotewiel M.

Free Radic Biol Med. 2009 Sep 15;47(6):803-13. doi: 10.1016/j.freeradbiomed.2009.06.021. Epub 2009 Jun 21.


A correlation of reactive oxygen species accumulation by depletion of superoxide dismutases with age-dependent impairment in the nervous system and muscles of Drosophila adults.

Oka S, Hirai J, Yasukawa T, Nakahara Y, Inoue YH.

Biogerontology. 2015 Aug;16(4):485-501. doi: 10.1007/s10522-015-9570-3. Epub 2015 Mar 24.


Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging.

Paul A, Belton A, Nag S, Martin I, Grotewiel MS, Duttaroy A.

Mech Ageing Dev. 2007 Nov-Dec;128(11-12):706-16. Epub 2007 Nov 4.


RNA interference-mediated silencing of Sod2 in Drosophila leads to early adult-onset mortality and elevated endogenous oxidative stress.

Kirby K, Hu J, Hilliker AJ, Phillips JP.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16162-7. Epub 2002 Nov 27.


Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging.

Mansouri A, Muller FL, Liu Y, Ng R, Faulkner J, Hamilton M, Richardson A, Huang TT, Epstein CJ, Van Remmen H.

Mech Ageing Dev. 2006 Mar;127(3):298-306. Epub 2006 Jan 6.


SOD2 contributes to anti-oxidative capacity in rabbit corneal endothelial cells.

Liu C, Ogando D, Bonanno JA.

Mol Vis. 2011;17:2473-81. Epub 2011 Sep 24.


Manipulation of Sod1 expression ubiquitously, but not in the nervous system or muscle, impacts age-related parameters in Drosophila.

Martin I, Jones MA, Grotewiel M.

FEBS Lett. 2009 Jul 7;583(13):2308-14. doi: 10.1016/j.febslet.2009.06.023. Epub 2009 Jun 18.


Mitochondrial superoxide radicals differentially affect muscle activity and neural function.

Godenschwege T, Forde R, Davis CP, Paul A, Beckwith K, Duttaroy A.

Genetics. 2009 Sep;183(1):175-84. doi: 10.1534/genetics.109.103515. Epub 2009 Jun 22.


Multiple measures of functionality exhibit progressive decline in a parallel, stochastic fashion in Drosophila Sod2 null mutants.

Piazza N, Hayes M, Martin I, Duttaroy A, Grotewiel M, Wessells R.

Biogerontology. 2009 Oct;10(5):637-48. doi: 10.1007/s10522-008-9210-2. Epub 2009 Jan 16.


Loss of parietal cell superoxide dismutase leads to gastric oxidative stress and increased injury susceptibility in mice.

Jones MK, Zhu E, Sarino EV, Padilla OR, Takahashi T, Shimizu T, Shirasawa T.

Am J Physiol Gastrointest Liver Physiol. 2011 Sep;301(3):G537-46. doi: 10.1152/ajpgi.00177.2011. Epub 2011 Jun 30.


Lifespan extension by cranberry supplementation partially requires SOD2 and is life stage independent.

Sun Y, Yolitz J, Alberico T, Sun X, Zou S.

Exp Gerontol. 2014 Feb;50:57-63. doi: 10.1016/j.exger.2013.11.020. Epub 2013 Dec 4.


Loss of manganese superoxide dismutase leads to abnormal growth and signal transduction in mouse embryonic fibroblasts.

Zhang Y, Zhang HM, Shi Y, Lustgarten M, Li Y, Qi W, Zhang BX, Van Remmen H.

Free Radic Biol Med. 2010 Nov 1;49(8):1255-62. doi: 10.1016/j.freeradbiomed.2010.07.006. Epub 2010 Jul 16.


SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness.

Friedman JS, Lopez MF, Fleming MD, Rivera A, Martin FM, Welsh ML, Boyd A, Doctrow SR, Burakoff SJ.

Blood. 2004 Oct 15;104(8):2565-73. Epub 2004 Jun 17.


Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice.

Williams MD, Van Remmen H, Conrad CC, Huang TT, Epstein CJ, Richardson A.

J Biol Chem. 1998 Oct 23;273(43):28510-5.


Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin.

Velarde MC, Flynn JM, Day NU, Melov S, Campisi J.

Aging (Albany NY). 2012 Jan;4(1):3-12.


Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis.

Kokoszka JE, Coskun P, Esposito LA, Wallace DC.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2278-83. Epub 2001 Feb 13.


Establishment of knockdown of superoxide dismutase 2 and expression of CYP3A4 cell system to evaluate drug-induced cytotoxicity.

Yoshikawa Y, Hosomi H, Fukami T, Nakajima M, Yokoi T.

Toxicol In Vitro. 2009 Sep;23(6):1179-87. doi: 10.1016/j.tiv.2009.05.024. Epub 2009 Jun 6.


Nimesulide-induced hepatic mitochondrial injury in heterozygous Sod2(+/-) mice.

Ong MM, Wang AS, Leow KY, Khoo YM, Boelsterli UA.

Free Radic Biol Med. 2006 Feb 1;40(3):420-9. Epub 2005 Nov 10.


Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin.

Liang LP, Waldbaum S, Rowley S, Huang TT, Day BJ, Patel M.

Neurobiol Dis. 2012 Mar;45(3):1068-76. doi: 10.1016/j.nbd.2011.12.025. Epub 2011 Dec 16.


Hypoxia rescues early mortality conferred by superoxide dismutase deficiency.

Wicks S, Bain N, Duttaroy A, Hilliker AJ, Phillips JP.

Free Radic Biol Med. 2009 Jan 15;46(2):176-81. doi: 10.1016/j.freeradbiomed.2008.09.036. Epub 2008 Oct 17.


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