Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 106


New insights into the regulation of T cells by gamma(c) family cytokines.

Rochman Y, Spolski R, Leonard WJ.

Nat Rev Immunol. 2009 Jul;9(7):480-90. doi: 10.1038/nri2580. Review.


Patients with T⁺/low NK⁺ IL-2 receptor γ chain deficiency have differentially-impaired cytokine signaling resulting in severe combined immunodeficiency.

Fuchs S, Rensing-Ehl A, Erlacher M, Vraetz T, Hartjes L, Janda A, Rizzi M, Lorenz MR, Gilmour K, de Saint-Basile G, Roifman CM, Cheuk S, Gennery A, Thrasher AJ, Fuchs I, Schwarz K, Speckmann C, Ehl S.

Eur J Immunol. 2014 Oct;44(10):3129-40. doi: 10.1002/eji.201444689. Epub 2014 Aug 28.


Implications for gene therapy-limiting expression of IL-2R gamma c delineate differences in signaling thresholds required for lymphocyte development and maintenance.

Orr SJ, Roessler S, Quigley L, Chan T, Ford JW, O'Connor GM, McVicar DW.

J Immunol. 2010 Aug 1;185(3):1393-403. doi: 10.4049/jimmunol.0903528. Epub 2010 Jun 30.


Thymic Determinants of γδ T Cell Differentiation.

Muñoz-Ruiz M, Sumaria N, Pennington DJ, Silva-Santos B.

Trends Immunol. 2017 May;38(5):336-344. doi: 10.1016/ Epub 2017 Mar 9. Review.


T+ NK+ IL-2 Receptor γ Chain Mutation: a Challenging Diagnosis of Atypical Severe Combined Immunodeficiency.

Stepensky P, Keller B, Shamriz O, von Spee-Mayer C, Friedmann D, Shadur B, Unger S, Fuchs S, NaserEddin A, Rumman N, Amro S, Molho Pessach V, Abuzaitoun O, Somech R, Elpeleg O, Ehl S, Warnatz K.

J Clin Immunol. 2018 May;38(4):527-536. doi: 10.1007/s10875-018-0514-y. Epub 2018 Jun 9.


Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy.

Liao W, Lin JX, Leonard WJ.

Immunity. 2013 Jan 24;38(1):13-25. doi: 10.1016/j.immuni.2013.01.004. Review.


TSLP signaling in CD4+ T cells programs a pathogenic T helper 2 cell state.

Rochman Y, Dienger-Stambaugh K, Richgels PK, Lewkowich IP, Kartashov AV, Barski A, Khurana Hershey GK, Leonard WJ, Singh H.

Sci Signal. 2018 Mar 13;11(521). pii: eaam8858. doi: 10.1126/scisignal.aam8858.


γδ T cells acquire effector fates in the thymus and differentiate into cytokine-producing effectors in a Listeria model of infection independently of CD28 costimulation.

Laird RM, Wolf BJ, Princiotta MF, Hayes SM.

PLoS One. 2013 May 9;8(5):e63178. doi: 10.1371/journal.pone.0063178. Print 2013.


IL-21 is the primary common γ chain-binding cytokine required for human B-cell differentiation in vivo.

Recher M, Berglund LJ, Avery DT, Cowan MJ, Gennery AR, Smart J, Peake J, Wong M, Pai SY, Baxi S, Walter JE, Palendira U, Tangye GA, Rice M, Brothers S, Al-Herz W, Oettgen H, Eibel H, Puck JM, Cattaneo F, Ziegler JB, Giliani S, Tangye SG, Notarangelo LD.

Blood. 2011 Dec 22;118(26):6824-35. doi: 10.1182/blood-2011-06-362533. Epub 2011 Oct 28.


The Common Cytokine Receptor γ Chain Family of Cytokines.

Lin JX, Leonard WJ.

Cold Spring Harb Perspect Biol. 2018 Sep 4;10(9). pii: a028449. doi: 10.1101/cshperspect.a028449. Review.


Differential Responsiveness of Innate-like IL-17- and IFN-γ-Producing γδ T Cells to Homeostatic Cytokines.

Corpuz TM, Stolp J, Kim HO, Pinget GV, Gray DH, Cho JH, Sprent J, Webster KE.

J Immunol. 2016 Jan 15;196(2):645-54. doi: 10.4049/jimmunol.1502082. Epub 2015 Dec 16.


Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism.

Levin SD, Koelling RM, Friend SL, Isaksen DE, Ziegler SF, Perlmutter RM, Farr AG.

J Immunol. 1999 Jan 15;162(2):677-83.


The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

Spits H, Di Santo JP.

Nat Immunol. 2011 Jan;12(1):21-7. doi: 10.1038/ni.1962. Epub 2010 Nov 28. Review.


Expression of common gamma chain signalling cytokines and their receptors distinguishes rejection from tolerance in a rat organ transplant model.

Ganbold A, Andersen S, Tay SS, Cunningham E, Ilie V, Krishnan S, Wang C, McCaughan GW, Sharland AF, Bishop GA.

Transpl Immunol. 2012 Oct;27(2-3):89-94. doi: 10.1016/j.trim.2012.08.001. Epub 2012 Aug 15.


Thymic stromal lymphopoietin converts human epidermal Langerhans cells into antigen-presenting cells that induce proallergic T cells.

Ebner S, Nguyen VA, Forstner M, Wang YH, Wolfram D, Liu YJ, Romani N.

J Allergy Clin Immunol. 2007 Apr;119(4):982-90. Epub 2007 Feb 22.


Ex vivo characterization of γδ T-cell repertoire in patients after adoptive transfer of Vγ9Vδ2 T cells expressing the interleukin-2 receptor β-chain and the common γ-chain.

Izumi T, Kondo M, Takahashi T, Fujieda N, Kondo A, Tamura N, Murakawa T, Nakajima J, Matsushita H, Kakimi K.

Cytotherapy. 2013 Apr;15(4):481-91. doi: 10.1016/j.jcyt.2012.12.004. Epub 2013 Feb 5.


T cell-mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells.

Hui CC, Murphy DM, Neighbour H, Al-Sayegh M, O'Byrne S, Thong B, Denburg JA, Larché M.

Clin Exp Allergy. 2014 Jul;44(7):953-64. doi: 10.1111/cea.12330.


The common γ-chain cytokine receptor: tricks-and-treats for T cells.

Waickman AT, Park JY, Park JH.

Cell Mol Life Sci. 2016 Jan;73(2):253-69. doi: 10.1007/s00018-015-2062-4. Epub 2015 Oct 14. Review.


Supplemental Content

Support Center