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Items: 1 to 20 of 177

1.

A single nucleotide polymorphism in the 3'UTR of the SNCA gene encoding alpha-synuclein is a new potential susceptibility locus for Parkinson disease.

Sotiriou S, Gibney G, Baxevanis AD, Nussbaum RL.

Neurosci Lett. 2009 Sep 18;461(2):196-201. doi: 10.1016/j.neulet.2009.06.034. Epub 2009 Jun 18.

2.

Variants in the 3'UTR of SNCA do not affect miRNA-433 binding and alpha-synuclein expression.

Schmitt I, Wüllner U, van Rooyen JP, Khazneh H, Becker J, Volk A, Kubisch C, Becker T, Kostic VS, Klein C, Ramirez A.

Eur J Hum Genet. 2012 Dec;20(12):1265-9. doi: 10.1038/ejhg.2012.84. Epub 2012 May 23.

3.

Lack of replication of a previously reported association between polymorphism in the 3'UTR of the alpha-synuclein gene and Parkinson's disease in Chinese subjects.

Hu FY, Hu WB, Liu L, Yu LH, Xi J, He XH, Zhu MR, Liu ZL, Xu YM.

Neurosci Lett. 2010 Jul 19;479(1):31-3. doi: 10.1016/j.neulet.2010.05.022. Epub 2010 May 15.

PMID:
20478361
4.

alpha-Synuclein and Parkinson disease susceptibility.

Winkler S, Hagenah J, Lincoln S, Heckman M, Haugarvoll K, Lohmann-Hedrich K, Kostic V, Farrer M, Klein C.

Neurology. 2007 Oct 30;69(18):1745-50. Epub 2007 Sep 13.

PMID:
17872362
5.
6.

Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease.

Ross OA, Gosal D, Stone JT, Lincoln SJ, Heckman MG, Irvine GB, Johnston JA, Gibson JM, Farrer MJ, Lynch T.

Mech Ageing Dev. 2007 May-Jun;128(5-6):378-82. Epub 2007 Apr 24.

7.

Analysis of polymorphisms in the 3' untranslated region of the LDL receptor gene and their effect on plasma cholesterol levels and drug response.

Chen W, Wang S, Ma Y, Zhou Y, Liu H, Strnad P, Kraemer FB, Krauss RM, Liu J.

Int J Mol Med. 2008 Mar;21(3):345-53.

PMID:
18288382
8.

SNCA and MAPT genes: Independent and joint effects in Parkinson disease in the Italian population.

Trotta L, Guella I, Soldà G, Sironi F, Tesei S, Canesi M, Pezzoli G, Goldwurm S, Duga S, Asselta R.

Parkinsonism Relat Disord. 2012 Mar;18(3):257-62. doi: 10.1016/j.parkreldis.2011.10.014. Epub 2011 Nov 21.

9.

SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.

Mata IF, Shi M, Agarwal P, Chung KA, Edwards KL, Factor SA, Galasko DR, Ginghina C, Griffith A, Higgins DS, Kay DM, Kim H, Leverenz JB, Quinn JF, Roberts JW, Samii A, Snapinn KW, Tsuang DW, Yearout D, Zhang J, Payami H, Zabetian CP.

Arch Neurol. 2010 Nov;67(11):1350-6. doi: 10.1001/archneurol.2010.279.

10.

The effect of SNCA 3' region on the levels of SNCA-112 splicing variant.

McCarthy JJ, Linnertz C, Saucier L, Burke JR, Hulette CM, Welsh-Bohmer KA, Chiba-Falek O.

Neurogenetics. 2011 Feb;12(1):59-64. doi: 10.1007/s10048-010-0263-4. Epub 2010 Nov 3.

11.

SNCA 3'UTR genetic variants in patients with Parkinson's disease and REM sleep behavior disorder.

Toffoli M, Dreussi E, Cecchin E, Valente M, Sanvilli N, Montico M, Gagno S, Garziera M, Polano M, Savarese M, Calandra-Buonaura G, Placidi F, Terzaghi M, Toffoli G, Gigli GL.

Neurol Sci. 2017 Apr 13. doi: 10.1007/s10072-017-2945-2. [Epub ahead of print]

PMID:
28409245
12.

Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease.

Mizuta I, Satake W, Nakabayashi Y, Ito C, Suzuki S, Momose Y, Nagai Y, Oka A, Inoko H, Fukae J, Saito Y, Sawabe M, Murayama S, Yamamoto M, Hattori N, Murata M, Toda T.

Hum Mol Genet. 2006 Apr 1;15(7):1151-8. Epub 2006 Feb 24.

PMID:
16500997
13.

YY1 binds to α-synuclein 3'-flanking region SNP and stimulates antisense noncoding RNA expression.

Mizuta I, Takafuji K, Ando Y, Satake W, Kanagawa M, Kobayashi K, Nagamori S, Shinohara T, Ito C, Yamamoto M, Hattori N, Murata M, Kanai Y, Murayama S, Nakagawa M, Toda T.

J Hum Genet. 2013 Nov;58(11):711-9. doi: 10.1038/jhg.2013.90. Epub 2013 Sep 12.

PMID:
24026176
14.

[SNCA rs356219 AND rs356165 VARIANTS ARE ASSOCIATED WITH PARKINSON'S DISEASE AND INCREASED ALPHA-SYNUCLEIN GENE EXPRESSION IN THE CD45(+)-BLOOD CELLS].

Emelyanov AK, Andoskin PA, Miliukhina IV, Timofeeva AA, Yakimovskii AF, Senkevich KA, Nikolaev MA, Pchelina SN.

Tsitologiia. 2016;58(2):99-104. Russian.

PMID:
27228655
15.
16.

The rs3756063 polymorphism is associated with SNCA methylation in the Chinese Han population.

Wei Y, Yang N, Xu Q, Sun Q, Guo J, Li K, Liu Z, Yan X, Zhu X, Tang B.

J Neurol Sci. 2016 Aug 15;367:11-4. doi: 10.1016/j.jns.2016.05.037. Epub 2016 May 19.

PMID:
27423554
17.

SNP rs356219 of the α-synuclein (SNCA) gene is associated with Parkinson's disease in a Chinese Han population.

Pan F, Dong H, Ding H, Ye M, Liu W, Wu Y, Zhang X, Chen Z, Luo Y, Ding X.

Parkinsonism Relat Disord. 2012 Jun;18(5):632-4. doi: 10.1016/j.parkreldis.2012.01.025. Epub 2012 Feb 19.

PMID:
22349157
18.

A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites.

Wirsing A, Senkel S, Klein-Hitpass L, Ryffel GU.

PLoS One. 2011;6(11):e27438. doi: 10.1371/journal.pone.0027438. Epub 2011 Nov 30.

19.

Alpha-synuclein (SNCA) polymorphisms and susceptibility to Parkinson's disease: a meta-analysis.

Han W, Liu Y, Mi Y, Zhao J, Liu D, Tian Q.

Am J Med Genet B Neuropsychiatr Genet. 2015 Mar;168B(2):123-34. doi: 10.1002/ajmg.b.32288. Epub 2015 Feb 5.

PMID:
25656566
20.

Genetic Variants of SNCA Are Associated with Susceptibility to Parkinson's Disease but Not Amyotrophic Lateral Sclerosis or Multiple System Atrophy in a Chinese Population.

Chen Y, Wei QQ, Ou R, Cao B, Chen X, Zhao B, Guo X, Yang Y, Chen K, Wu Y, Song W, Shang HF.

PLoS One. 2015 Jul 24;10(7):e0133776. doi: 10.1371/journal.pone.0133776. eCollection 2015.

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