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In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation.

Viatte L, Gröne HJ, Hentze MW, Galy B.

J Mol Med (Berl). 2009 Sep;87(9):913-21. doi: 10.1007/s00109-009-0494-8. Epub 2009 Jun 17.


Excess capacity of the iron regulatory protein system.

Wang W, Di X, D'Agostino RB Jr, Torti SV, Torti FM.

J Biol Chem. 2007 Aug 24;282(34):24650-9. Epub 2007 Jun 28.


Changes of gene expression of iron regulatory proteins during turpentine oil-induced acute-phase response in the rat.

Sheikh N, Dudas J, Ramadori G.

Lab Invest. 2007 Jul;87(7):713-25. Epub 2007 Apr 9.


Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins.

Sanchez M, Galy B, Schwanhaeusser B, Blake J, Bähr-Ivacevic T, Benes V, Selbach M, Muckenthaler MU, Hentze MW.

Blood. 2011 Nov 24;118(22):e168-79. doi: 10.1182/blood-2011-04-343541. Epub 2011 Sep 22.


Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis.

Meyron-Holtz EG, Ghosh MC, Iwai K, LaVaute T, Brazzolotto X, Berger UV, Land W, Ollivierre-Wilson H, Grinberg A, Love P, Rouault TA.

EMBO J. 2004 Jan 28;23(2):386-95. Epub 2004 Jan 15.


Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum.

Galy B, Ferring-Appel D, Kaden S, Gröne HJ, Hentze MW.

Cell Metab. 2008 Jan;7(1):79-85. doi: 10.1016/j.cmet.2007.10.006.


Expression and biochemical characterization of iron regulatory proteins 1 and 2 in Saccharomyces cerevisiae.

Phillips JD, Guo B, Yu Y, Brown FM, Leibold EA.

Biochemistry. 1996 Dec 10;35(49):15704-14.


IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice.

Corna G, Galy B, Hentze MW, Cairo G.

J Mol Med (Berl). 2006 Jul;84(7):551-60. Epub 2006 Jun 13.


Iron regulatory proteins 1 and 2 in human monocytes, macrophages and duodenum: expression and regulation in hereditary hemochromatosis and iron deficiency.

Recalcati S, Alberghini A, Campanella A, Gianelli U, De Camilli E, Conte D, Cairo G.

Haematologica. 2006 Mar;91(3):303-10. Epub 2006 Feb 17.


Ferroportin-1 is a 'nuclear'-negative acute-phase protein in rat liver: a comparison with other iron-transport proteins.

Naz N, Malik IA, Sheikh N, Ahmad S, Khan S, Blaschke M, Schultze F, Ramadori G.

Lab Invest. 2012 Jun;92(6):842-56. doi: 10.1038/labinvest.2012.52.


Generation of conditional alleles of the murine Iron Regulatory Protein (IRP)-1 and -2 genes.

Galy B, Ferring D, Hentze MW.

Genesis. 2005 Dec;43(4):181-8.


Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2).

Galy B, Ferring D, Minana B, Bell O, Janser HG, Muckenthaler M, Schümann K, Hentze MW.

Blood. 2005 Oct 1;106(7):2580-9. Epub 2005 Jun 14.


STAT3 signaling within hepatocytes is required for anemia of inflammation in vivo.

Sakamori R, Takehara T, Tatsumi T, Shigekawa M, Hikita H, Hiramatsu N, Kanto T, Hayashi N.

J Gastroenterol. 2010 Feb;45(2):244-8. doi: 10.1007/s00535-009-0159-y. Epub 2009 Dec 1.


Differential regulation of IRP1 and IRP2 by nitric oxide in rat hepatoma cells.

Phillips JD, Kinikini DV, Yu Y, Guo B, Leibold EA.

Blood. 1996 Apr 1;87(7):2983-92.


Mammalian tissue oxygen levels modulate iron-regulatory protein activities in vivo.

Meyron-Holtz EG, Ghosh MC, Rouault TA.

Science. 2004 Dec 17;306(5704):2087-90.


Iron regulatory protein 1 is not required for the modulation of ferritin and transferrin receptor expression by iron in a murine pro-B lymphocyte cell line.

Schalinske KL, Blemings KP, Steffen DW, Chen OS, Eisenstein RS.

Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10681-6.


Hypoxia post-translationally activates iron-regulatory protein 2.

Hanson ES, Foot LM, Leibold EA.

J Biol Chem. 1999 Feb 19;274(8):5047-52.

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