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Items: 1 to 20 of 108

1.

In the light of directed evolution: pathways of adaptive protein evolution.

Bloom JD, Arnold FH.

Proc Natl Acad Sci U S A. 2009 Jun 16;106 Suppl 1:9995-10000. doi: 10.1073/pnas.0901522106. Epub 2009 Jun 15. Review.

2.

Exploring protein fitness landscapes by directed evolution.

Romero PA, Arnold FH.

Nat Rev Mol Cell Biol. 2009 Dec;10(12):866-76. doi: 10.1038/nrm2805. Review.

3.

How proteins adapt: lessons from directed evolution.

Arnold FH.

Cold Spring Harb Symp Quant Biol. 2009;74:41-6. doi: 10.1101/sqb.2009.74.046. Epub 2010 Apr 22. Review.

PMID:
20413708
4.

Protein promiscuity: drug resistance and native functions--HIV-1 case.

Fernández A, Tawfik DS, Berkhout B, Sanders R, Kloczkowski A, Sen T, Jernigan B.

J Biomol Struct Dyn. 2005 Jun;22(6):615-24.

PMID:
15842167
5.

Probing the mutational interplay between primary and promiscuous protein functions: a computational-experimental approach.

Garcia-Seisdedos H, Ibarra-Molero B, Sanchez-Ruiz JM.

PLoS Comput Biol. 2012;8(6):e1002558. doi: 10.1371/journal.pcbi.1002558. Epub 2012 Jun 14.

6.

Rational evolutionary design: the theory of in vitro protein evolution.

Voigt CA, Kauffman S, Wang ZG.

Adv Protein Chem. 2000;55:79-160. Review.

PMID:
11050933
7.

How protein stability and new functions trade off.

Tokuriki N, Stricher F, Serrano L, Tawfik DS.

PLoS Comput Biol. 2008 Feb 29;4(2):e1000002. doi: 10.1371/journal.pcbi.1000002.

8.

Molecular Clock of Neutral Mutations in a Fitness-Increasing Evolutionary Process.

Kishimoto T, Ying BW, Tsuru S, Iijima L, Suzuki S, Hashimoto T, Oyake A, Kobayashi H, Someya Y, Narisawa D, Yomo T.

PLoS Genet. 2015 Jul 15;11(7):e1005392. doi: 10.1371/journal.pgen.1005392. eCollection 2015 Jul.

9.

Stability effects of mutations and protein evolvability.

Tokuriki N, Tawfik DS.

Curr Opin Struct Biol. 2009 Oct;19(5):596-604. doi: 10.1016/j.sbi.2009.08.003. Epub 2009 Sep 16. Review.

PMID:
19765975
10.

Intense neutral drifts yield robust and evolvable consensus proteins.

Bershtein S, Goldin K, Tawfik DS.

J Mol Biol. 2008 Jun 20;379(5):1029-44. doi: 10.1016/j.jmb.2008.04.024. Epub 2008 Apr 16.

PMID:
18495157
11.
12.

Laboratory-directed protein evolution.

Yuan L, Kurek I, English J, Keenan R.

Microbiol Mol Biol Rev. 2005 Sep;69(3):373-92. Review.

13.

Evolution favors protein mutational robustness in sufficiently large populations.

Bloom JD, Lu Z, Chen D, Raval A, Venturelli OS, Arnold FH.

BMC Biol. 2007 Jul 17;5:29.

14.

Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes.

Studer RA, Dessailly BH, Orengo CA.

Biochem J. 2013 Feb 1;449(3):581-94. doi: 10.1042/BJ20121221. Review.

PMID:
23301657
15.

Modulating protein stability - directed evolution strategies for improved protein function.

Socha RD, Tokuriki N.

FEBS J. 2013 Nov;280(22):5582-95. doi: 10.1111/febs.12354. Epub 2013 Jun 18. Review.

16.

The spectrum of adaptive mutations in experimental evolution.

Lang GI, Desai MM.

Genomics. 2014 Dec;104(6 Pt A):412-6. doi: 10.1016/j.ygeno.2014.09.011. Epub 2014 Sep 28. Review.

17.

Protein stability promotes evolvability.

Bloom JD, Labthavikul ST, Otey CR, Arnold FH.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5869-74. Epub 2006 Mar 31.

18.

Experimental evolution of adenylate kinase reveals contrasting strategies toward protein thermostability.

Miller C, Davlieva M, Wilson C, White KI, Cou├▒ago R, Wu G, Myers JC, Wittung-Stafshede P, Shamoo Y.

Biophys J. 2010 Aug 4;99(3):887-96. doi: 10.1016/j.bpj.2010.04.076.

19.

Biophysics of protein evolution and evolutionary protein biophysics.

Sikosek T, Chan HS.

J R Soc Interface. 2014 Nov 6;11(100):20140419. doi: 10.1098/rsif.2014.0419. Erratum in: J R Soc Interface. 2015 Nov 6;12(112). pii: 20150915. doi: 10.1098/rsif.2015.0915.

20.

Natural history as a predictor of protein evolvability.

O'Loughlin TL, Patrick WM, Matsumura I.

Protein Eng Des Sel. 2006 Oct;19(10):439-42. Epub 2006 Jul 25. Review.

PMID:
16868005

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