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Items: 1 to 20 of 90

1.

Functional consequences of the subdomain organization of the sulfs.

Tang R, Rosen SD.

J Biol Chem. 2009 Aug 7;284(32):21505-14. doi: 10.1074/jbc.M109.028472. Epub 2009 Jun 11.

2.
3.

Sulf loss influences N-, 2-O-, and 6-O-sulfation of multiple heparan sulfate proteoglycans and modulates fibroblast growth factor signaling.

Lamanna WC, Frese MA, Balleininger M, Dierks T.

J Biol Chem. 2008 Oct 10;283(41):27724-35. doi: 10.1074/jbc.M802130200. Epub 2008 Aug 6.

4.
5.

Measuring the activities of the Sulfs: two novel heparin/heparan sulfate endosulfatases.

Uchimura K, Morimoto-Tomita M, Rosen SD.

Methods Enzymol. 2006;416:243-53.

PMID:
17113870
6.

Drosophila heparan sulfate 6-O-endosulfatase Sulf1 facilitates wingless (Wg) protein degradation.

Kleinschmit A, Takemura M, Dejima K, Choi PY, Nakato H.

J Biol Chem. 2013 Feb 15;288(7):5081-9. doi: 10.1074/jbc.M112.447029. Epub 2013 Jan 7.

7.

Proteolytic cleavage of the rat heparan sulfate 6-O-endosulfatase SulfFP2 by furin-type proprotein convertases.

Nagamine S, Keino-Masu K, Shiomi K, Masu M.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):107-12. doi: 10.1016/j.bbrc.2009.11.011. Epub 2009 Nov 10.

PMID:
19900405
8.

The SULFs, extracellular sulfatases for heparan sulfate, promote the migration of corneal epithelial cells during wound repair.

Maltseva I, Chan M, Kalus I, Dierks T, Rosen SD.

PLoS One. 2013 Aug 8;8(8):e69642. doi: 10.1371/journal.pone.0069642. eCollection 2013.

9.

Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.

Lemjabbar-Alaoui H, van Zante A, Singer MS, Xue Q, Wang YQ, Tsay D, He B, Jablons DM, Rosen SD.

Oncogene. 2010 Feb 4;29(5):635-46. doi: 10.1038/onc.2009.365. Epub 2009 Oct 26.

10.

Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2.

Ai X, Do AT, Kusche-Gullberg M, Lindahl U, Lu K, Emerson CP Jr.

J Biol Chem. 2006 Feb 24;281(8):4969-76. Epub 2005 Dec 23.

11.

Use of a phage display antibody to measure the enzymatic activity of the Sulfs.

Uchimura K, Lemjabbar-Alaoui H, van Kuppevelt TH, Rosen SD.

Methods Enzymol. 2010;480:51-64. doi: 10.1016/S0076-6879(10)80003-5. Review.

PMID:
20816204
12.

SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation.

Ai X, Kitazawa T, Do AT, Kusche-Gullberg M, Labosky PA, Emerson CP Jr.

Development. 2007 Sep;134(18):3327-38.

13.

[Sulfs: extracellular endosulfatases that regulate physiological functions of heparan sulfate].

Uchimura K.

Seikagaku. 2011 Mar;83(3):216-23. Review. Japanese. No abstract available.

PMID:
21516688
14.

Sulf-2: an extracellular modulator of cell signaling and a cancer target candidate.

Rosen SD, Lemjabbar-Alaoui H.

Expert Opin Ther Targets. 2010 Sep;14(9):935-49. doi: 10.1517/14728222.2010.504718. Review.

15.

Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.

Morimoto-Tomita M, Uchimura K, Werb Z, Hemmerich S, Rosen SD.

J Biol Chem. 2002 Dec 20;277(51):49175-85. Epub 2002 Oct 3.

16.

Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer.

Morimoto-Tomita M, Uchimura K, Bistrup A, Lum DH, Egeblad M, Boudreau N, Werb Z, Rosen SD.

Neoplasia. 2005 Nov;7(11):1001-10.

17.

Substrate specificity of 6-O-endosulfatase (Sulf-2) and its implications in synthesizing anticoagulant heparan sulfate.

Pempe EH, Burch TC, Law CJ, Liu J.

Glycobiology. 2012 Oct;22(10):1353-62. doi: 10.1093/glycob/cws092. Epub 2012 Jun 12.

18.

HpSulf, a heparan sulfate 6-O-endosulfatase, is involved in the regulation of VEGF signaling during sea urchin development.

Fujita K, Takechi E, Sakamoto N, Sumiyoshi N, Izumi S, Miyamoto T, Matsuura S, Tsurugaya T, Akasaka K, Yamamoto T.

Mech Dev. 2010 Apr;127(3-4):235-45. doi: 10.1016/j.mod.2009.12.001. Epub 2009 Dec 29.

19.

Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche.

Langsdorf A, Schumacher V, Shi X, Tran T, Zaia J, Jain S, Taglienti M, Kreidberg JA, Fine A, Ai X.

Glycobiology. 2011 Feb;21(2):152-61. doi: 10.1093/glycob/cwq133. Epub 2010 Sep 20.

20.

HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.

Dai Y, Yang Y, MacLeod V, Yue X, Rapraeger AC, Shriver Z, Venkataraman G, Sasisekharan R, Sanderson RD.

J Biol Chem. 2005 Dec 2;280(48):40066-73. Epub 2005 Sep 27.

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