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Items: 1 to 20 of 92


Characterization of a potent non-cytotoxic shRNA directed to the HIV-1 co-receptor CCR5.

Shimizu S, Kamata M, Kittipongdaja P, Chen KN, Kim S, Pang S, Boyer J, Qin FX, An DS, Chen IS.

Genet Vaccines Ther. 2009 Jun 10;7:8. doi: 10.1186/1479-0556-7-8.


Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors.

An DS, Qin FX, Auyeung VC, Mao SH, Kung SK, Baltimore D, Chen IS.

Mol Ther. 2006 Oct;14(4):494-504. Epub 2006 Jul 17.


High-throughput screening of effective siRNAs using luciferase-linked chimeric mRNA.

Pang S, Pokomo L, Chen K, Kamata M, Mao SH, Zhang H, Razi E, An DS, Chen IS.

PLoS One. 2014 May 15;9(5):e96445. doi: 10.1371/journal.pone.0096445. eCollection 2014.


Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100.

Maczuga P, Koornneef A, Borel F, Petry H, van Deventer S, Ritsema T, Konstantinova P.

BMC Biotechnol. 2012 Jul 24;12:42. doi: 10.1186/1472-6750-12-42.


Titers of HIV-based vectors encoding shRNAs are reduced by a dicer-dependent mechanism.

Poluri A, Sutton RE.

Mol Ther. 2008 Feb;16(2):378-86. Epub 2007 Dec 11.


Lentiviral Vector Design for Multiple shRNA Expression and Durable HIV-1 Inhibition.

Brake OT, Hooft K', Liu YP, Centlivre M, Jasmijn von Eije K, Berkhout B.

Mol Ther. 2008 Mar;16(3):557-564. doi: 10.1038/ Epub 2016 Dec 8.


Characterisation and comparison of the chicken H1 RNA polymerase III promoter for short hairpin RNA expression.

Cummins DM, Tyack SG, Doran TJ.

Biochem Biophys Res Commun. 2011 Dec 9;416(1-2):194-8. doi: 10.1016/j.bbrc.2011.11.024. Epub 2011 Nov 10.


Construction of simple and efficient DNA vector-based short hairpin RNA expression systems for specific gene silencing in mammalian cells.

Cheng TL, Chang WT.

Methods Mol Biol. 2007;408:223-41. doi: 10.1007/978-1-59745-547-3_13.


Characterisation and application of a bovine U6 promoter for expression of short hairpin RNAs.

Lambeth LS, Moore RJ, Muralitharan M, Dalrymple BP, McWilliam S, Doran TJ.

BMC Biotechnol. 2005 May 11;5:13.


Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition.

ter Brake O, 't Hooft K, Liu YP, Centlivre M, von Eije KJ, Berkhout B.

Mol Ther. 2008 Mar;16(3):557-64. doi: 10.1038/ Epub 2008 Jan 15.


Stringent testing identifies highly potent and escape-proof anti-HIV short hairpin RNAs.

von Eije KJ, ter Brake O, Berkhout B.

J Gene Med. 2009 Jun;11(6):459-67. doi: 10.1002/jgm.1329.


Comparison of chicken 7SK and U6 RNA polymerase III promoters for short hairpin RNA expression.

Bannister SC, Wise TG, Cahill DM, Doran TJ.

BMC Biotechnol. 2007 Nov 19;7:79.


Selection of potent non-toxic inhibitory sequences from a randomized HIV-1 specific lentiviral short hairpin RNA library.

Pongratz C, Yazdanpanah B, Kashkar H, Lehmann MJ, Kräusslich HG, Krönke M.

PLoS One. 2010 Oct 8;5(10):e13172. doi: 10.1371/journal.pone.0013172.


Multiplexing seven miRNA-Based shRNAs to suppress HIV replication.

Choi JG, Bharaj P, Abraham S, Ma H, Yi G, Ye C, Dang Y, Manjunath N, Wu H, Shankar P.

Mol Ther. 2015 Feb;23(2):310-20. doi: 10.1038/mt.2014.205. Epub 2014 Oct 31.


Rapid assessment of anti-HIV siRNA efficacy using PCR-derived Pol III shRNA cassettes.

Scherer LJ, Yildiz Y, Kim J, Cagnon L, Heale B, Rossi JJ.

Mol Ther. 2004 Sep;10(3):597-603.


Production of transgenic pigs that express porcine endogenous retrovirus small interfering RNAs.

Ramsoondar J, Vaught T, Ball S, Mendicino M, Monahan J, Jobst P, Vance A, Duncan J, Wells K, Ayares D.

Xenotransplantation. 2009 May-Jun;16(3):164-80. doi: 10.1111/j.1399-3089.2009.00525.x.


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