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Items: 1 to 20 of 118


Evaluating protocols for embryonic stem cell differentiation into insulin-secreting beta-cells using insulin II-GFP as a specific and noninvasive reporter.

Ben-Yehudah A, White C, Navara CS, Castro CA, Ize-Ludlow D, Shaffer B, Sukhwani M, Mathews CE, Chaillet JR, Witchel SF.

Cloning Stem Cells. 2009 Jun;11(2):245-57. doi: 10.1089/clo.2008.0074.


INS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells.

Micallef SJ, Li X, Schiesser JV, Hirst CE, Yu QC, Lim SM, Nostro MC, Elliott DA, Sarangi F, Harrison LC, Keller G, Elefanty AG, Stanley EG.

Diabetologia. 2012 Mar;55(3):694-706. doi: 10.1007/s00125-011-2379-y. Epub 2011 Nov 26.


A new experimental protocol for preferential differentiation of mouse embryonic stem cells into insulin-producing cells.

Naujok O, Francini F, Picton S, Jörns A, Bailey CJ, Lenzen S.

Cell Transplant. 2008;17(10-11):1231-42.


The combined expression of Pdx1 and MafA with either Ngn3 or NeuroD improves the differentiation efficiency of mouse embryonic stem cells into insulin-producing cells.

Xu H, Tsang KS, Chan JC, Yuan P, Fan R, Kaneto H, Xu G.

Cell Transplant. 2013;22(1):147-58. doi: 10.3727/096368912X653057. Epub 2012 Jul 5.


Differential effect of activin on mouse embryonic stem cell differentiation in insulin-secreting cells under nestin-positive selection and spontaneous differentiation protocols.

Jafary H, Larijani B, Farrokhi A, Pirouz M, Mollamohammadi S, Baharvand H.

Cell Biol Int. 2008 Feb;32(2):278-86. Epub 2007 Oct 7.


Differentiation and transplantation of functional pancreatic beta cells generated from induced pluripotent stem cells derived from a type 1 diabetes mouse model.

Jeon K, Lim H, Kim JH, Thuan NV, Park SH, Lim YM, Choi HY, Lee ER, Kim JH, Lee MS, Cho SG.

Stem Cells Dev. 2012 Sep 20;21(14):2642-55. doi: 10.1089/scd.2011.0665. Epub 2012 Jun 1.


Characterization of an in vitro differentiation assay for pancreatic-like cell development from murine embryonic stem cells: detailed gene expression analysis.

Chen C, Chai J, Singh L, Kuo CY, Jin L, Feng T, Marzano S, Galeni S, Zhang N, Iacovino M, Qin L, Hara M, Stein R, Bromberg JS, Kyba M, Ku HT.

Assay Drug Dev Technol. 2011 Aug;9(4):403-19. doi: 10.1089/adt.2010.0314. Epub 2011 Mar 11.


The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells.

Basford CL, Prentice KJ, Hardy AB, Sarangi F, Micallef SJ, Li X, Guo Q, Elefanty AG, Stanley EG, Keller G, Allister EM, Nostro MC, Wheeler MB.

Diabetologia. 2012 Feb;55(2):358-71. doi: 10.1007/s00125-011-2335-x. Epub 2011 Nov 11.


Differentiation of COPAS-sorted non-endocrine pancreatic cells into insulin-positive cells in the mouse.

Kikugawa R, Katsuta H, Akashi T, Yatoh S, Weir GC, Sharma A, Bonner-Weir S.

Diabetologia. 2009 Apr;52(4):645-52. doi: 10.1007/s00125-009-1260-8. Epub 2009 Jan 30.


Human embryonic stem cell differentiation into insulin secreting β-cells for diabetes.

Bose B, Shenoy SP, Konda S, Wangikar P.

Cell Biol Int. 2012 Nov 1;36(11):1013-20. doi: 10.1042/CBI20120210.


Generation of embryonic stem cells from mouse insulin I promoter-green fluorescent protein transgenic mice and characterization in a teratoma model.

Milewski WM, Temple KA, Wesselschmidt RL, Hara M.

In Vitro Cell Dev Biol Anim. 2009 Jan-Feb;45(1-2):1-5. doi: 10.1007/s11626-008-9142-9. Epub 2008 Oct 15.


An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells.

Naujok O, Francini F, Jörns A, Lenzen S.

Cell Prolif. 2008 Aug;41(4):607-24. doi: 10.1111/j.1365-2184.2008.00541.x. Epub 2008 Jun 19.


Single pancreatic beta cells co-express multiple islet hormone genes in mice.

Katsuta H, Akashi T, Katsuta R, Nagaya M, Kim D, Arinobu Y, Hara M, Bonner-Weir S, Sharma AJ, Akashi K, Weir GC.

Diabetologia. 2010 Jan;53(1):128-38. doi: 10.1007/s00125-009-1570-x. Epub 2009 Oct 23.


Generation of functional insulin-producing cells from human embryonic stem cells in vitro.

Shi Y.

Methods Mol Biol. 2010;636:79-85. doi: 10.1007/978-1-60761-691-7_5.


A comparison of protocols used to generate insulin-producing cell clusters from mouse embryonic stem cells.

Boyd AS, Wu DC, Higashi Y, Wood KJ.

Stem Cells. 2008 May;26(5):1128-37. doi: 10.1634/stemcells.2007-0762. Epub 2008 Mar 6.


Morphological differentiation of tau-green fluorescent protein embryonic stem cells into neurons after co-culture with auditory brain stem slices.

Glavaski-Joksimovic A, Thonabulsombat C, Wendt M, Eriksson M, Ma H, Olivius P.

Neuroscience. 2009 Aug 18;162(2):472-81. doi: 10.1016/j.neuroscience.2009.04.070. Epub 2009 May 3.


Insulin-producing cells derived from human embryonic stem cells: comparison of definitive endoderm- and nestin-positive progenitor-based differentiation strategies.

Wei R, Yang J, Hou W, Liu G, Gao M, Zhang L, Wang H, Mao G, Gao H, Chen G, Hong T.

PLoS One. 2013 Aug 12;8(8):e72513. doi: 10.1371/journal.pone.0072513. eCollection 2013.


High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells.

Hakim F, Kaitsuka T, Raeed JM, Wei FY, Shiraki N, Akagi T, Yokota T, Kume S, Tomizawa K.

J Biol Chem. 2014 Apr 4;289(14):9623-38. doi: 10.1074/jbc.M113.524363. Epub 2014 Feb 19.


Efficient definitive endoderm induction from mouse embryonic stem cell adherent cultures: a rapid screening model for differentiation studies.

Mfopou JK, Geeraerts M, Dejene R, Van Langenhoven S, Aberkane A, Van Grunsven LA, Bouwens L.

Stem Cell Res. 2014 Jan;12(1):166-77. doi: 10.1016/j.scr.2013.10.004. Epub 2013 Oct 23.

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