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Items: 1 to 20 of 68

1.

PUMA suppresses intestinal tumorigenesis in mice.

Qiu W, Carson-Walter EB, Kuan SF, Zhang L, Yu J.

Cancer Res. 2009 Jun 15;69(12):4999-5006. doi: 10.1158/0008-5472.CAN-09-0262. Epub 2009 Jun 2.

2.

Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis.

Qiu W, Leibowitz B, Zhang L, Yu J.

Oncogene. 2010 Mar 18;29(11):1622-32. doi: 10.1038/onc.2009.451. Epub 2009 Dec 7.

3.

p53 and PUMA independently regulate apoptosis of intestinal epithelial cells in patients and mice with colitis.

Dirisina R, Katzman RB, Goretsky T, Managlia E, Mittal N, Williams DB, Qiu W, Yu J, Chandel NS, Zhang L, Barrett TA.

Gastroenterology. 2011 Sep;141(3):1036-45. doi: 10.1053/j.gastro.2011.05.032. Epub 2011 May 27.

4.

PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice.

Qiu W, Wu B, Wang X, Buchanan ME, Regueiro MD, Hartman DJ, Schoen RE, Yu J, Zhang L.

J Clin Invest. 2011 May;121(5):1722-32. doi: 10.1172/JCI42917. Epub 2011 Apr 1.

5.

Enhanced colon carcinogenesis induced by azoxymethane in min mice occurs via a mechanism independent of beta-catenin mutation.

Suzui M, Okuno M, Tanaka T, Nakagama H, Moriwaki H.

Cancer Lett. 2002 Sep 8;183(1):31-41.

PMID:
12049812
6.

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.

Li P, Schulz S, Bombonati A, Palazzo JP, Hyslop TM, Xu Y, Baran AA, Siracusa LD, Pitari GM, Waldman SA.

Gastroenterology. 2007 Aug;133(2):599-607. Epub 2007 Jun 2.

PMID:
17681179
7.

Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer.

Volate SR, Muga SJ, Issa AY, Nitcheva D, Smith T, Wargovich MJ.

Mol Carcinog. 2009 Oct;48(10):920-33. doi: 10.1002/mc.20542.

8.

Voluntary exercise inhibits intestinal tumorigenesis in Apc(Min/+) mice and azoxymethane/dextran sulfate sodium-treated mice.

Ju J, Nolan B, Cheh M, Bose M, Lin Y, Wagner GC, Yang CS.

BMC Cancer. 2008 Nov 2;8:316. doi: 10.1186/1471-2407-8-316.

9.

Zinc induces expression of the BH3-only protein PUMA through p53 and ERK pathways in SH-SY5Y neuroblastoma cells.

Hara H, Kamiya T, Adachi T.

Neurochem Res. 2009 Aug;34(8):1498-506. doi: 10.1007/s11064-009-9937-4. Epub 2009 Feb 25.

PMID:
19241161
10.

The BH3-only protein, PUMA, is involved in oxaliplatin-induced apoptosis in colon cancer cells.

Wang X, Li M, Wang J, Yeung CM, Zhang H, Kung HF, Jiang B, Lin MC.

Biochem Pharmacol. 2006 May 28;71(11):1540-50. Epub 2006 Apr 3.

PMID:
16595125
11.

PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells.

Ming L, Wang P, Bank A, Yu J, Zhang L.

J Biol Chem. 2006 Jun 9;281(23):16034-42. Epub 2006 Apr 11.

12.

Qualitative and quantitative relationship between dysplastic aberrant crypt foci and tumorigenesis in the Min/+ mouse colon.

Paulsen JE, Steffensen IL, Løberg EM, Husøy T, Namork E, Alexander J.

Cancer Res. 2001 Jul 1;61(13):5010-5.

13.

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.

Villunger A, Michalak EM, Coultas L, Müllauer F, Böck G, Ausserlechner MJ, Adams JM, Strasser A.

Science. 2003 Nov 7;302(5647):1036-8. Epub 2003 Sep 18.

14.

Sodium taurocholate inhibits intestinal adenoma formation in APCMin/+ mice, potentially through activation of the farnesoid X receptor.

Smith DL, Keshavan P, Avissar U, Ahmed K, Zucker SD.

Carcinogenesis. 2010 Jun;31(6):1100-9. doi: 10.1093/carcin/bgq050. Epub 2010 Mar 1.

15.

Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice.

Yang W, Velcich A, Lozonschi I, Liang J, Nicholas C, Zhuang M, Bancroft L, Augenlicht LH.

Am J Pathol. 2005 Apr;166(4):1239-46.

16.

Inactivation of the vitamin D receptor in APC(min/+) mice reveals a critical role for the vitamin D receptor in intestinal tumor growth.

Zheng W, Wong KE, Zhang Z, Dougherty U, Mustafi R, Kong J, Deb DK, Zheng H, Bissonnette M, Li YC.

Int J Cancer. 2012 Jan 1;130(1):10-9. doi: 10.1002/ijc.25992. Epub 2011 Apr 20.

17.

Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells.

Kang DW, Choi CY, Cho YH, Tian H, Di Paolo G, Choi KY, Min do S.

J Exp Med. 2015 Jul 27;212(8):1219-37. doi: 10.1084/jem.20141254. Epub 2015 Jun 29.

18.

Age-dependent susceptibility to azoxymethane-induced and spontaneous tumorigenesis in the Min/+ mouse.

Paulsen JE, Steffensen IL, Namork E, Eide TJ, Alexander J.

Anticancer Res. 2003 Jan-Feb;23(1A):259-65.

PMID:
12680222
19.

PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.

Qiu W, Wang X, Leibowitz B, Yang W, Zhang L, Yu J.

Hepatology. 2011 Oct;54(4):1249-58. doi: 10.1002/hep.24516.

20.

Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis.

Zeilstra J, Joosten SP, Dokter M, Verwiel E, Spaargaren M, Pals ST.

Cancer Res. 2008 May 15;68(10):3655-61. doi: 10.1158/0008-5472.CAN-07-2940.

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