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Items: 1 to 20 of 481

1.

The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1.

Jenal M, Trinh E, Britschgi C, Britschgi A, Roh V, Vorburger SA, Tobler A, Leprince D, Fey MF, Helin K, Tschan MP.

Mol Cancer Res. 2009 Jun;7(6):916-22. doi: 10.1158/1541-7786.MCR-08-0359. Epub 2009 Jun 2.

2.

Identification of the p53 family-responsive element in the promoter region of the tumor suppressor gene hypermethylated in cancer 1.

Britschgi C, Rizzi M, Grob TJ, Tschan MP, Hügli B, Reddy VA, Andres AC, Torbett BE, Tobler A, Fey MF.

Oncogene. 2006 Mar 30;25(14):2030-9.

PMID:
16301995
3.

Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients.

Tseng RC, Lee CC, Hsu HS, Tzao C, Wang YC.

Neoplasia. 2009 Aug;11(8):763-70.

4.

Transcriptional regulation of the mouse PNRC2 promoter by the nuclear factor Y (NFY) and E2F1.

Zhou D, Masri S, Ye JJ, Chen S.

Gene. 2005 Nov 21;361:89-100. Epub 2005 Sep 21.

PMID:
16181749
5.

E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer.

Lu Z, Luo RZ, Peng H, Huang M, Nishmoto A, Hunt KK, Helin K, Liao WS, Yu Y.

Oncogene. 2006 Jan 12;25(2):230-9.

PMID:
16158053
6.
7.

Implication of HIC1 (Hypermethylated In Cancer 1) in the DNA damage response.

Dehennaut V, Leprince D.

Bull Cancer. 2009 Nov;96(11):E66-72. doi: 10.1684/bdc.2009.0959. Review.

8.

8-Chloro-adenosine-induced E2F1 promotes p14ARF gene activation in H1299 cells through displacing Sp1 from multiple overlapping E2F1/Sp1 sites.

Zhang HJ, Li WJ, Yang SY, Li SY, Ni JH, Jia HT.

J Cell Biochem. 2009 Feb 15;106(3):464-72. doi: 10.1002/jcb.22033.

PMID:
19115249
9.

Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1.

Maenz B, Hekerman P, Vela EM, Galceran J, Becker W.

BMC Mol Biol. 2008 Mar 26;9:30. doi: 10.1186/1471-2199-9-30.

10.

Transcription factor E2F1 is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene.

Schayek H, Bentov I, Rotem I, Pasmanik-Chor M, Ginsberg D, Plymate SR, Werner H.

Growth Horm IGF Res. 2010 Feb;20(1):68-72. doi: 10.1016/j.ghir.2009.08.001. Epub 2009 Aug 22.

PMID:
19703789
11.

Activating E2Fs mediate transcriptional regulation of human E2F6 repressor.

Lyons TE, Salih M, Tuana BS.

Am J Physiol Cell Physiol. 2006 Jan;290(1):C189-99. Epub 2005 Aug 17.

12.

HIC1 interacts with a specific subunit of SWI/SNF complexes, ARID1A/BAF250A.

Van Rechem C, Boulay G, Leprince D.

Biochem Biophys Res Commun. 2009 Aug 7;385(4):586-90. doi: 10.1016/j.bbrc.2009.05.115. Epub 2009 May 30.

PMID:
19486893
13.

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses.

Chen WY, Wang DH, Yen RC, Luo J, Gu W, Baylin SB.

Cell. 2005 Nov 4;123(3):437-48.

14.

Scavenger chemokine (CXC motif) receptor 7 (CXCR7) is a direct target gene of HIC1 (hypermethylated in cancer 1).

Van Rechem C, Rood BR, Touka M, Pinte S, Jenal M, Guérardel C, Ramsey K, Monté D, Bégue A, Tschan MP, Stephan DA, Leprince D.

J Biol Chem. 2009 Jul 31;284(31):20927-35. doi: 10.1074/jbc.M109.022350. Epub 2009 Jun 12.

15.

Inactivation of the hypermethylated in cancer 1 tumour suppressor--not just a question of promoter hypermethylation?

Jenal M, Britschgi C, Fey MF, Tschan MP.

Swiss Med Wkly. 2010 Nov 1;140:w13106. doi: 10.4414/smw.2010.13106. Review.

16.
17.

DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function.

Britschgi A, Trinh E, Rizzi M, Jenal M, Ress A, Tobler A, Fey MF, Helin K, Tschan MP.

Oncogene. 2008 Sep 25;27(43):5706-16. doi: 10.1038/onc.2008.179. Epub 2008 Jun 2.

PMID:
18521079
18.

p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes.

Truscott M, Harada R, Vadnais C, Robert F, Nepveu A.

Mol Cell Biol. 2008 May;28(10):3127-38. doi: 10.1128/MCB.02089-07. Epub 2008 Mar 17.

19.

CDCA4 is an E2F transcription factor family-induced nuclear factor that regulates E2F-dependent transcriptional activation and cell proliferation.

Hayashi R, Goto Y, Ikeda R, Yokoyama KK, Yoshida K.

J Biol Chem. 2006 Nov 24;281(47):35633-48. Epub 2006 Sep 19.

20.

HIC1 tumour suppressor gene is suppressed in acute myeloid leukaemia and induced during granulocytic differentiation.

Britschgi C, Jenal M, Rizzi M, Mueller BU, Torbett BE, Andres AC, Tobler A, Fey MF, Tschan MP.

Br J Haematol. 2008 Apr;141(2):179-87. doi: 10.1111/j.1365-2141.2008.06992.x. Epub 2008 Mar 3.

PMID:
18318772

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