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Items: 1 to 20 of 95

1.

Intestinal mucosal inflammation leads to systemic genotoxicity in mice.

Westbrook AM, Wei B, Braun J, Schiestl RH.

Cancer Res. 2009 Jun 1;69(11):4827-34. doi: 10.1158/0008-5472.CAN-08-4416.

2.

Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation.

Westbrook AM, Schiestl RH.

Cancer Res. 2010 Mar 1;70(5):1875-84. doi: 10.1158/0008-5472.CAN-09-2584. Epub 2010 Feb 23.

3.

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

Rodrigues-Sousa T, Ladeirinha AF, Santiago AR, Carvalheiro H, Raposo B, Alarcão A, Cabrita A, Holmdahl R, Carvalho L, Souto-Carneiro MM.

PLoS One. 2014 May 29;9(5):e97532. doi: 10.1371/journal.pone.0097532. eCollection 2014.

4.

Intestinal inflammation induces genotoxicity to extraintestinal tissues and cell types in mice.

Westbrook AM, Wei B, Braun J, Schiestl RH.

Int J Cancer. 2011 Oct 15;129(8):1815-25. doi: 10.1002/ijc.26146. Epub 2011 Aug 2.

5.

Dextran sulfate sodium-induced ulcerative colitis leads to increased hematopoiesis and induces both local as well as systemic genotoxicity in mice.

Trivedi PP, Jena GB.

Mutat Res. 2012 May 15;744(2):172-83. doi: 10.1016/j.mrgentox.2012.03.001. Epub 2012 Mar 10.

PMID:
22414559
6.

Role of α-lipoic acid in dextran sulfate sodium-induced ulcerative colitis in mice: studies on inflammation, oxidative stress, DNA damage and fibrosis.

Trivedi PP, Jena GB.

Food Chem Toxicol. 2013 Sep;59:339-55. doi: 10.1016/j.fct.2013.06.019. Epub 2013 Jun 20.

PMID:
23793040
7.

IEX-1 deficiency protects against colonic cancer.

Ustyugova IV, Zhi L, Abramowitz J, Birnbaumer L, Wu MX.

Mol Cancer Res. 2012 Jun;10(6):760-7. doi: 10.1158/1541-7786.MCR-11-0556. Epub 2012 May 1.

8.

Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: therapeutic efficacy and possible mechanisms of action.

Yousef M, Pichyangkura R, Soodvilai S, Chatsudthipong V, Muanprasat C.

Pharmacol Res. 2012 Jul;66(1):66-79. doi: 10.1016/j.phrs.2012.03.013. Epub 2012 Mar 28.

PMID:
22475725
9.

Role of metallothionein in murine experimental colitis.

Tsuji T, Naito Y, Takagi T, Kugai M, Yoriki H, Horie R, Fukui A, Mizushima K, Hirai Y, Katada K, Kamada K, Uchiyama K, Handa O, Konishi H, Yagi N, Ichikawa H, Yanagisawa R, Suzuki JS, Takano H, Satoh M, Yoshikawa T.

Int J Mol Med. 2013 May;31(5):1037-46. doi: 10.3892/ijmm.2013.1294. Epub 2013 Mar 6.

PMID:
23467591
10.

Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.

Shen Y, Ma J, Yan R, Ling H, Li X, Yang W, Gao J, Huang C, Bu Y, Cao Y, He Y, Wan L, Zu X, Liu J, Huang MC, Stenson WF, Liao DF, Cao D.

Clin Cancer Res. 2015 Mar 15;21(6):1466-76. doi: 10.1158/1078-0432.CCR-14-2072. Epub 2014 Dec 23.

11.

TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation.

Takedatsu H, Michelsen KS, Wei B, Landers CJ, Thomas LS, Dhall D, Braun J, Targan SR.

Gastroenterology. 2008 Aug;135(2):552-67. doi: 10.1053/j.gastro.2008.04.037. Epub 2008 May 7.

12.

The role of tumour necrosis factor-α and tumour necrosis factor receptor signalling in inflammation-associated systemic genotoxicity.

Westbrook AM, Wei B, Hacke K, Xia M, Braun J, Schiestl RH.

Mutagenesis. 2012 Jan;27(1):77-86. doi: 10.1093/mutage/ger063. Epub 2011 Oct 6.

13.

Anti-inflammatory mechanism of metformin and its effects in intestinal inflammation and colitis-associated colon cancer.

Koh SJ, Kim JM, Kim IK, Ko SH, Kim JS.

J Gastroenterol Hepatol. 2014 Mar;29(3):502-10.

PMID:
24716225
14.

Development of colonic neoplasms and expressions of p53 and p21 proteins in experimental colitis of mice induced by dextran sulfate sodium.

Takesue F, Korenaga D, Yao T, Kabashima A, Sugimachi K.

J Exp Clin Cancer Res. 2001 Sep;20(3):413-8.

PMID:
11718223
15.

Investigating intestinal inflammation in DSS-induced model of IBD.

Kim JJ, Shajib MS, Manocha MM, Khan WI.

J Vis Exp. 2012 Feb 1;(60). pii: 3678. doi: 10.3791/3678.

16.

Opposite effects of interferon regulatory factor 1 and osteopontin on the apoptosis of epithelial cells induced by TNF-α in inflammatory bowel disease.

Tang R, Yang G, Zhang S, Wu C, Chen M.

Inflamm Bowel Dis. 2014 Nov;20(11):1950-61. doi: 10.1097/MIB.0000000000000192.

PMID:
25208103
17.

Mitochondrial gene polymorphisms that protect mice from colitis.

Bär F, Bochmann W, Widok A, von Medem K, Pagel R, Hirose M, Yu X, Kalies K, König P, Böhm R, Herdegen T, Reinicke AT, Büning J, Lehnert H, Fellermann K, Ibrahim S, Sina C.

Gastroenterology. 2013 Nov;145(5):1055-1063.e3. doi: 10.1053/j.gastro.2013.07.015. Epub 2013 Jul 19.

PMID:
23872498
18.

IL-10 modulates DSS-induced colitis through a macrophage-ROS-NO axis.

Li B, Alli R, Vogel P, Geiger TL.

Mucosal Immunol. 2014 Jul;7(4):869-78. doi: 10.1038/mi.2013.103. Epub 2013 Dec 4.

19.

Mast cell deficiency exacerbates inflammatory bowel symptoms in interleukin-10-deficient mice.

Zhang H, Xue Y, Wang H, Huang Y, Du M, Yang Q, Zhu MJ.

World J Gastroenterol. 2014 Jul 21;20(27):9106-15. doi: 10.3748/wjg.v20.i27.9106.

20.

Prebiotic treatment in experimental colitis reduces the risk of colitic cancer.

Komiyama Y, Mitsuyama K, Masuda J, Yamasaki H, Takedatsu H, Andoh A, Tsuruta O, Fukuda M, Kanauchi O.

J Gastroenterol Hepatol. 2011 Aug;26(8):1298-308. doi: 10.1111/j.1440-1746.2011.06690.x.

PMID:
21303406

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