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19481313,21434800,12669468,17287053,17414400,15755595,15893613,17630051,23857274,17941821,15196569,15193387,16645985,20923270,15970361,16673438,22368926,19622040,19485754,18043565,18838420,16460845,17996338,15475985,15475986,31506309,14711328,17712231,18623907,22607895,17494638,15597071,20483197,16028126,15597072,19384263,15149774,16682101,29048985,16861642,16955685,16621189,23256737,15755600,31024540,15755593,32037226,22883368,28495657,25662856,19397410,16242221,21803101,17289223,23416222,28624305,16469496,19751688,20844462,21604979,22537024,17065257,16553812,9554288,20188677,22883369,15755594,16257096,19477560,20954968,19464093,28487177,35080470,19209097,1812432,12908514,19553555,21489881,1812425,17212760,21832882,19325450,29543582,10353890,31242158,21604983,21911024,15681142,6427703,18617296,24476428,15315478,22085175,15755597,21434801,21785281,29083947,10227322,1812438,20113980,17875437,16026250,19322255,20072946,24486354,21489883,15597070,11398116,1357461,25982025,23856330,9554266,19837092,18636953,33290434,17921703,12186274,22230578,10438363,18801401,26093201,19481315,15755596,21615224,17168998,21803107,19213536,7505873,22234267,11738731,7757351,22607900,23984957,17615088,15755601,3091433,26116255,11474010,28356256,15485333,18988650,20619376,15501782,25424810,29667483,10462229,15993990,17931164,23427430,12439801,22658929,1812430,16487298,22178525,18804134,16621173,16879900,17494636,15755602,18571105,16190134,15609780,15307001,12717625,16823908,23903040,12654777,15297049,21904120,30551148,22947250,26390123,18252172,1907153,15780445,19717104,19109451,20410516,19761833,10448985,11727513,17544180,25882169,11031849,15161082,12531351,17635804,25986879,15339202,7752883,15961591,19528146,28375029,21452513,11301813,17524531,15039094,15964482,26204792,15695689,18364764,1812424,17706408,16677743,21255369,25997113,23305865,24679664,19477562,19476428,19162117,24815780,16595570,27104935,20144017,21083312,22867717,19717106,22464965,27158988,17762777,36207900,19485753,19100804,22607893,17548136,18187240,19883161,7551027,23372704,15780576,19325452,24631075,17184222,14639545,17052819,22607894,19607954,15378443,20653107,15080262,15695688,17240485,22461527,7927704,15460638,28369428,19534597,22607898,11988262,18505380,15597069,3134548,9805079,17707961,31383485,26147212,22426368,3089660,1812439,17678419,11483265,9078586,9530542,35610106,22138211,11031854,12051059,36957984,23273968,26865595,18161897,17466419,9916109,19486642,17158897,35642527,16470164,23458443,19737898,102231,19180164,8873395,11179386,16321460,20518335,17168995,14741154,15578323,19200847,16224557,17521780,21865879,17125663,11731951,33309166,25017717,17449149,8559044,28778616,1812423,19477559,9488382,10770724,2492123,32335565,31839469,2110462,11031853,16776648,17517451,10334064,26912077,21255149,10225920,16456881,24521624,19555901,19943757,17378929,16914236,17691125,21993655,17643560,17446054,16513914,18491322,19060937,16046037,22984187,1812426,23521186,10225908,8606350,16115701,15380644,15051544,21604975,17660718,16517032,23213659,6436785,23251421,19159627,17015517,6417339,16685767,19325447,26590434,23410224,14746525,19738334,15995271,25396230,17848884,19095025,19200820,11885731,10618543,34793713,19428890,11303261,28394704,19168106,21785283,10887587,8156052,18452423,19500554,30697213,19717110,19477053,1812428,19654065,19249967,25417906,18425153,30886228,2367188,24696308,19209096,11535115,22827308,17233633,16989625,12696001,9498448,11523943,11203416,27191543,3143885,11163678,23741478,19377283,20372072,19289516,11237833,17620353,16709528,24462403,34498079,17537176,17658670,15481128,25905795,19534873,22260987,10418910,17972966,21136768,16965350,3130778,15296275,15702048,17664268,19023262,24715891,17499399,20067752,21148522,15120002,12179916,19779400,18640169,18378363,1812427,25625525,28992986,19684470,2128606,12015462,16125824,20009513,7670576,12076272,19137557,21794204,25637287,30687793,11401992,23296384,33752953,19421058,6809629,15849905,17936445,1963725,19200816,25249532,15691503,19063929,17391939,15320887,8718585,12077873,12973866,22699443,21336749,9987144,17630052,18160186,19356620,17981083,19186206,17052822,4212159,31048732,19333079,19888731,1812440,32695289,10084899,31202503,12089113,17669003,29136861,19935538,1803695,18984023,8464406,33223554,19093465,26844997,20148042,15972495,14530350,31202504,23437524,9125592,17969240,19056945,18359952,30307136,11527011,18479979,10518045,11833953,30182092,17635531,25733557,14980172,31442078,11807696,11567765,27567106,9005944,25496172,18364765,6425085,24294728,30285743,28705462,30120070,17038831,27745811,19477563,12942396,27481244,19771612,19480581,19803757,18174321,19627182,24162638,19444153,33950776,24448573,19116603,18983283,16765397,19040035,16470851,19482754,18391897,18430496,19400026,15832260,26042357,28935107,19526652,19337336,19385941,21364778,3146194,19026504,19561669,16893582,19507626,18256346,19100746,21337138,32591792,27177946,17521783,15745746,19863236,8275404,22487332,17418547,18031983,11665934,37045859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Properties and clinical performance of vaccines containing outer membrane vesicles from Neisseria meningitidis.

Holst J, Martin D, Arnold R, Huergo CC, Oster P, O'Hallahan J, Rosenqvist E. Holst J, et al. Vaccine. 2009 Jun 24;27 Suppl 2:B3-12. doi: 10.1016/j.vaccine.2009.04.071. Epub 2009 May 28. Vaccine. 2009. PMID: 19481313 Review.

Adjuvant properties of meningococcal outer membrane vesicles and the use of adjuvants in Neisseria meningitidis protein vaccines.

Sanders H, Feavers IM. Sanders H, et al. Expert Rev Vaccines. 2011 Mar;10(3):323-34. doi: 10.1586/erv.11.10. Expert Rev Vaccines. 2011. PMID: 21434800 Review.

Recent developments in vaccines to prevent meningococcal serogroup B infections.

Vermont CL, van den Dobbelsteen GP, de Groot R. Vermont CL, et al. Curr Opin Mol Ther. 2003 Feb;5(1):33-8. Curr Opin Mol Ther. 2003. PMID: 12669468 Review.

Safety review: two outer membrane vesicle (OMV) vaccines against systemic Neisseria meningitidis serogroup B disease.

Nøkleby H, Aavitsland P, O'Hallahan J, Feiring B, Tilman S, Oster P. Nøkleby H, et al. Vaccine. 2007 Apr 20;25(16):3080-4. doi: 10.1016/j.vaccine.2007.01.022. Epub 2007 Jan 22. Vaccine. 2007. PMID: 17287053

New zealand epidemic strain meningococcal B outer membrane vesicle vaccine in children aged 16-24 months.

Wong S, Lennon D, Jackson C, Stewart J, Reid S, Crengle S, Tilman S, Aaberge I, O'Hallahan J, Oster P, Mulholland K, Martin D. Wong S, et al. Pediatr Infect Dis J. 2007 Apr;26(4):345-50. doi: 10.1097/01.inf.0000258697.05341.2c. Pediatr Infect Dis J. 2007. PMID: 17414400 Clinical Trial.

The concept of "tailor-made", protein-based, outer membrane vesicle vaccines against meningococcal disease.

Holst J, Feiring B, Naess LM, Norheim G, Kristiansen P, Høiby EA, Bryn K, Oster P, Costantino P, Taha MK, Alonso JM, Caugant DA, Wedege E, Aaberge IS, Rappuoli R, Rosenqvist E. Holst J, et al. Vaccine. 2005 Mar 18;23(17-18):2202-5. doi: 10.1016/j.vaccine.2005.01.058. Vaccine. 2005. PMID: 15755595

Development and characterisation of outer membrane vesicle vaccines against serogroup A Neisseria meningitidis.

Norheim G, Aase A, Caugant DA, Høiby EA, Fritzsønn E, Tangen T, Kristiansen P, Heggelund U, Rosenqvist E. Norheim G, et al. Vaccine. 2005 May 31;23(29):3762-74. doi: 10.1016/j.vaccine.2005.02.021. Epub 2005 Mar 14. Vaccine. 2005. PMID: 15893613

Re: Safety review: Two outer membrane vesicle (OMV) vaccines against systemic Neisseria meningitidis serogroup B disease, Nokleby H, Aavitsland P, O'Hallahan J, Feiring B, Tilman S, Oster P. Vaccine 2007;25(16):3080-4.

Lennon D. Lennon D. Vaccine. 2007 Sep 28;25(39-40):6833; author reply 6833-4. doi: 10.1016/j.vaccine.2007.06.024. Epub 2007 Jun 21. Vaccine. 2007. PMID: 17630051 No abstract available.

Vaccines against meningococcal serogroup B disease containing outer membrane vesicles (OMV): lessons from past programs and implications for the future.

Holst J, Oster P, Arnold R, Tatley MV, Næss LM, Aaberge IS, Galloway Y, McNicholas A, O'Hallahan J, Rosenqvist E, Black S. Holst J, et al. Hum Vaccin Immunother. 2013 Jun;9(6):1241-53. doi: 10.4161/hv.24129. Epub 2013 Mar 7. Hum Vaccin Immunother. 2013. PMID: 23857274 Free PMC article. Review.

Postgenomics of Neisseria meningitidis for vaccines development.

Bernardini G, Braconi D, Martelli P, Santucci A. Bernardini G, et al. Expert Rev Proteomics. 2007 Oct;4(5):667-77. doi: 10.1586/14789450.4.5.667. Expert Rev Proteomics. 2007. PMID: 17941821 Review.

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