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Items: 1 to 20 of 276

1.

Processing bodies are not required for mammalian nonsense-mediated mRNA decay.

Stalder L, Mühlemann O.

RNA. 2009 Jul;15(7):1265-73. doi: 10.1261/rna.1672509. Epub 2009 May 27.

2.

UPF1 P-body localization.

Brogna S, Ramanathan P, Wen J.

Biochem Soc Trans. 2008 Aug;36(Pt 4):698-700. doi: 10.1042/BST0360698. Review.

PMID:
18631143
3.

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.

Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S.

Genes Dev. 2006 Feb 1;20(3):355-67.

4.

Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways.

Metze S, Herzog VA, Ruepp MD, Mühlemann O.

RNA. 2013 Oct;19(10):1432-48. doi: 10.1261/rna.038893.113. Epub 2013 Aug 20.

5.

Nonsense-mediated mRNA decay impacts MSI-driven carcinogenesis and anti-tumor immunity in colorectal cancers.

El-Bchiri J, Guilloux A, Dartigues P, Loire E, Mercier D, Buhard O, Sobhani I, de la Grange P, Auboeuf D, Praz F, Fléjou JF, Duval A.

PLoS One. 2008 Jul 9;3(7):e2583. doi: 10.1371/journal.pone.0002583.

6.

Inhibition of nonsense-mediated mRNA decay (NMD) by a new chemical molecule reveals the dynamic of NMD factors in P-bodies.

Durand S, Cougot N, Mahuteau-Betzer F, Nguyen CH, Grierson DS, Bertrand E, Tazi J, Lejeune F.

J Cell Biol. 2007 Sep 24;178(7):1145-60.

7.

CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells.

Hosoda N, Kim YK, Lejeune F, Maquat LE.

Nat Struct Mol Biol. 2005 Oct;12(10):893-901. Epub 2005 Sep 25.

PMID:
16186820
8.
9.

CK2-mediated TEL2 phosphorylation augments nonsense-mediated mRNA decay (NMD) by increase of SMG1 stability.

Ahn S, Kim J, Hwang J.

Biochim Biophys Acta. 2013 Oct;1829(10):1047-55. doi: 10.1016/j.bbagrm.2013.06.002. Epub 2013 Jul 3.

10.

Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of Ullrich disease fibroblasts.

Usuki F, Yamashita A, Kashima I, Higuchi I, Osame M, Ohno S.

Mol Ther. 2006 Sep;14(3):351-60. Epub 2006 Jun 27.

11.

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways.

Ivanov PV, Gehring NH, Kunz JB, Hentze MW, Kulozik AE.

EMBO J. 2008 Mar 5;27(5):736-47. doi: 10.1038/emboj.2008.17. Epub 2008 Feb 7.

12.

Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors.

Nicholson P, Yepiskoposyan H, Metze S, Zamudio Orozco R, Kleinschmidt N, Mühlemann O.

Cell Mol Life Sci. 2010 Mar;67(5):677-700. doi: 10.1007/s00018-009-0177-1. Epub 2009 Oct 27. Review.

PMID:
19859661
13.

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay.

Kim YK, Furic L, Desgroseillers L, Maquat LE.

Cell. 2005 Jan 28;120(2):195-208.

14.

Human INT6/eIF3e is required for nonsense-mediated mRNA decay.

Morris C, Wittmann J, Jäck HM, Jalinot P.

EMBO Rep. 2007 Jun;8(6):596-602. Epub 2007 Apr 20.

15.

Genetic background affects relative nonsense mRNA accumulation in wild-type and upf mutant yeast strains.

Kebaara B, Nazarenus T, Taylor R, Atkin AL.

Curr Genet. 2003 Jun;43(3):171-7. Epub 2003 Apr 15.

PMID:
12695845
16.

Targeting of aberrant mRNAs to cytoplasmic processing bodies.

Sheth U, Parker R.

Cell. 2006 Jun 16;125(6):1095-109.

17.

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity.

Chamieh H, Ballut L, Bonneau F, Le Hir H.

Nat Struct Mol Biol. 2008 Jan;15(1):85-93. Epub 2007 Dec 9.

PMID:
18066079
18.

Incomplete nonsense-mediated mRNA decay in Giardia lamblia.

Chen YH, Su LH, Sun CH.

Int J Parasitol. 2008 Sep;38(11):1305-17. doi: 10.1016/j.ijpara.2008.02.006. Epub 2008 Mar 21.

PMID:
18430426
19.

hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay.

Wittmann J, Hol EM, Jäck HM.

Mol Cell Biol. 2006 Feb;26(4):1272-87.

20.

Inactivation of NMD increases viability of sup45 nonsense mutants in Saccharomyces cerevisiae.

Chabelskaya S, Gryzina V, Moskalenko S, Le Goff C, Zhouravleva G.

BMC Mol Biol. 2007 Aug 16;8:71.

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