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Items: 1 to 20 of 114

1.

RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.

Larrea MD, Hong F, Wander SA, da Silva TG, Helfman D, Lannigan D, Smith JA, Slingerland JM.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9268-73. doi: 10.1073/pnas.0805057106. Epub 2009 May 22.

2.

Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4.

Larrea MD, Liang J, Da Silva T, Hong F, Shao SH, Han K, Dumont D, Slingerland JM.

Mol Cell Biol. 2008 Oct;28(20):6462-72. doi: 10.1128/MCB.02300-07. Epub 2008 Aug 18.

3.

p27 as Jekyll and Hyde: regulation of cell cycle and cell motility.

Larrea MD, Wander SA, Slingerland JM.

Cell Cycle. 2009 Nov 1;8(21):3455-61. Epub 2009 Nov 11.

PMID:
19829074
4.

Akt-dependent T198 phosphorylation of cyclin-dependent kinase inhibitor p27kip1 in breast cancer.

Motti ML, De Marco C, Califano D, Fusco A, Viglietto G.

Cell Cycle. 2004 Aug;3(8):1074-80. Epub 2004 Aug 7.

PMID:
15280662
5.

p90 ribosomal S6 kinase 1 (RSK1) isoenzyme specifically regulates cytokinesis progression.

Nam HJ, Lee IJ, Jang S, Bae CD, Kwak SJ, Lee JH.

Cell Signal. 2014 Feb;26(2):208-19. doi: 10.1016/j.cellsig.2013.11.014. Epub 2013 Nov 19.

PMID:
24269382
6.

p27Kip1 modulates cell migration through the regulation of RhoA activation.

Besson A, Gurian-West M, Schmidt A, Hall A, Roberts JM.

Genes Dev. 2004 Apr 15;18(8):862-76. Epub 2004 Apr 12.

7.

Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration.

Yang S, Ji M, Zhang L, Chen Y, Wennmann DO, Kremerskothen J, Dong J.

Cell Signal. 2014 Feb;26(2):343-51. doi: 10.1016/j.cellsig.2013.11.012. Epub 2013 Nov 19.

8.

C-terminal phosphorylation controls the stability and function of p27kip1.

Kossatz U, Vervoorts J, Nickeleit I, Sundberg HA, Arthur JS, Manns MP, Malek NP.

EMBO J. 2006 Nov 1;25(21):5159-70. Epub 2006 Oct 19.

10.

ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.

Lenferink AE, Busse D, Flanagan WM, Yakes FM, Arteaga CL.

Cancer Res. 2001 Sep 1;61(17):6583-91.

11.

Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localization.

Motti ML, Califano D, Troncone G, De Marco C, Migliaccio I, Palmieri E, Pezzullo L, Palombini L, Fusco A, Viglietto G.

Am J Pathol. 2005 Mar;166(3):737-49.

12.
13.

The N-terminal region of p27 inhibits HIF-1α protein translation in ribosomal protein S6-dependent manner by regulating PHLPP-Ras-ERK-p90RSK axis.

Zhang D, Liu J, Mi X, Liang Y, Li J, Huang C.

Cell Death Dis. 2014 Nov 20;5:e1535. doi: 10.1038/cddis.2014.496.

14.

Rsk1 mediates a MEK-MAP kinase cell survival signal.

Shimamura A, Ballif BA, Richards SA, Blenis J.

Curr Biol. 2000 Feb 10;10(3):127-35.

15.
16.

Effect of cyclin E overexpression on lovastatin-induced G1 arrest and RhoA inactivation in NIH3T3 cells.

Ghosh PM, Moyer ML, Mott GE, Kreisberg JI.

J Cell Biochem. 1999 Sep 15;74(4):532-43.

PMID:
10440923
17.

Increased cytoplasmic localization of p27(kip1) and its modulation of RhoA activity during progression of chronic myeloid leukemia.

Roy A, Lahiry L, Banerjee D, Ghosh M, Banerjee S.

PLoS One. 2013 Oct 1;8(10):e76527. doi: 10.1371/journal.pone.0076527. eCollection 2013.

19.

p27Kip1 promotes migration of metastatic hepatocellular carcinoma cells.

Wang XQ, Lui EL, Cai Q, Ching WY, Liu KS, Poon RT, Fan ST.

Tumour Biol. 2008;29(4):217-23. doi: 10.1159/000152939. Epub 2008 Sep 9.

PMID:
18781093
20.

RhoA regulates G1-S progression of gastric cancer cells by modulation of multiple INK4 family tumor suppressors.

Zhang S, Tang Q, Xu F, Xue Y, Zhen Z, Deng Y, Liu M, Chen J, Liu S, Qiu M, Liao Z, Li Z, Luo D, Shi F, Zheng Y, Bi F.

Mol Cancer Res. 2009 Apr;7(4):570-80. doi: 10.1158/1541-7786.MCR-08-0248.

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