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Items: 1 to 20 of 88

1.

Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development.

Freeman-Anderson NE, Zheng Y, McCalla-Martin AC, Treanor LM, Zhao YD, Garfin PM, He TC, Mary MN, Thornton JD, Anderson C, Gibbons M, Saab R, Baumer SH, Cunningham JM, Skapek SX.

Development. 2009 Jun;136(12):2081-9. doi: 10.1242/dev.033548.

2.

Tgfbeta signaling directly induces Arf promoter remodeling by a mechanism involving Smads 2/3 and p38 MAPK.

Zheng Y, Zhao YD, Gibbons M, Abramova T, Chu PY, Ash JD, Cunningham JM, Skapek SX.

J Biol Chem. 2010 Nov 12;285(46):35654-64. doi: 10.1074/jbc.M110.128959. Epub 2010 Sep 8.

3.

A distant, cis-acting enhancer drives induction of Arf by Tgfβ in the developing eye.

Zheng Y, Devitt C, Liu J, Mei J, Skapek SX.

Dev Biol. 2013 Aug 1;380(1):49-57. doi: 10.1016/j.ydbio.2013.05.003. Epub 2013 May 9.

4.

Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.

Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2004 Jun 4;279(23):24745-56. Epub 2004 Mar 25.

5.

Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice.

Goumans MJ, Mummery C.

Int J Dev Biol. 2000 Apr;44(3):253-65. Review.

6.

p19(Arf) limits primary vitreous cell proliferation driven by PDGF-B.

Iqbal NS, Devitt CC, Sung CY, Skapek SX.

Exp Eye Res. 2016 Apr;145:224-9. doi: 10.1016/j.exer.2016.01.004. Epub 2016 Jan 8.

7.

Persistent hyperplastic primary vitreous due to somatic mosaic deletion of the arf tumor suppressor.

Thornton JD, Swanson DJ, Mary MN, Pei D, Martin AC, Pounds S, Goldowitz D, Skapek SX.

Invest Ophthalmol Vis Sci. 2007 Feb;48(2):491-9.

PMID:
17251441
8.

Suppression of tumorigenesis and induction of p15(ink4b) by Smad4/DPC4 in human pancreatic cancer cells.

Peng B, Fleming JB, Breslin T, Grau AM, Fojioka S, Abbruzzese JL, Evans DB, Ayers D, Wathen K, Wu T, Robertson KD, Chiao PJ.

Clin Cancer Res. 2002 Nov;8(11):3628-38.

9.

The alternative reading frame tumor suppressor inhibits growth through p21-dependent and p21-independent pathways.

Modestou M, Puig-Antich V, Korgaonkar C, Eapen A, Quelle DE.

Cancer Res. 2001 Apr 1;61(7):3145-50.

10.

Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a.

Alani RM, Young AZ, Shifflett CB.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7812-6. Epub 2001 Jun 26.

11.

Transforming growth factor beta-1 enhances Smad transcriptional activity through activation of p8 gene expression.

García-Montero AC, Vasseur S, Giono LE, Canepa E, Moreno S, Dagorn JC, Iovanna JL.

Biochem J. 2001 Jul 1;357(Pt 1):249-53.

12.

Mechanisms of mitotic inhibition in corneal endothelium: contact inhibition and TGF-beta2.

Joyce NC, Harris DL, Mello DM.

Invest Ophthalmol Vis Sci. 2002 Jul;43(7):2152-9.

PMID:
12091410
13.
14.

miR-34a is essential for p19(Arf)-driven cell cycle arrest.

Iqbal N, Mei J, Liu J, Skapek SX.

Cell Cycle. 2014;13(5):792-800. doi: 10.4161/cc.27725. Epub 2014 Jan 8.

15.
16.

Inhibition of v-Abl transformation by p53 and p19ARF.

Cong F, Zou X, Hinrichs K, Calame K, Goff SP.

Oncogene. 1999 Dec 16;18(54):7731-9.

17.

p19Arf represses platelet-derived growth factor receptor β by transcriptional and posttranscriptional mechanisms.

Widau RC, Zheng Y, Sung CY, Zelivianskaia A, Roach LE, Bachmeyer KM, Abramova T, Desgardin A, Rosner A, Cunningham JM, Skapek SX.

Mol Cell Biol. 2012 Nov;32(21):4270-82. doi: 10.1128/MCB.06424-11. Epub 2012 Aug 20.

19.

Pathogenesis of persistent hyperplastic primary vitreous in mice lacking the arf tumor suppressor gene.

Martin AC, Thornton JD, Liu J, Wang X, Zuo J, Jablonski MM, Chaum E, Zindy F, Skapek SX.

Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3387-96.

20.

Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway.

Akool el-S, Doller A, Müller R, Gutwein P, Xin C, Huwiler A, Pfeilschifter J, Eberhardt W.

J Biol Chem. 2005 Nov 25;280(47):39403-16. Epub 2005 Sep 23.

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