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Items: 1 to 20 of 166

1.

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I.

Gack MU, Albrecht RA, Urano T, Inn KS, Huang IC, Carnero E, Farzan M, Inoue S, Jung JU, García-Sastre A.

Cell Host Microbe. 2009 May 8;5(5):439-49. doi: 10.1016/j.chom.2009.04.006.

2.

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU.

PLoS Pathog. 2012;8(11):e1003059. doi: 10.1371/journal.ppat.1003059. Epub 2012 Nov 29.

3.

Robust Lys63-Linked Ubiquitination of RIG-I Promotes Cytokine Eruption in Early Influenza B Virus Infection.

Jiang J, Li J, Fan W, Zheng W, Yu M, Chen C, Sun L, Bi Y, Ding C, Gao GF, Liu W.

J Virol. 2016 Jun 24;90(14):6263-75. doi: 10.1128/JVI.00549-16. Print 2016 Jul 15.

4.

Activation of duck RIG-I by TRIM25 is independent of anchored ubiquitin.

Miranzo-Navarro D, Magor KE.

PLoS One. 2014 Jan 23;9(1):e86968. doi: 10.1371/journal.pone.0086968. eCollection 2014.

5.

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity.

Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU.

Nature. 2007 Apr 19;446(7138):916-920.

PMID:
17392790
6.

A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses.

Oshiumi H, Miyashita M, Matsumoto M, Seya T.

PLoS Pathog. 2013;9(8):e1003533. doi: 10.1371/journal.ppat.1003533. Epub 2013 Aug 8.

7.

The ubiquitin-specific protease USP15 promotes RIG-I-mediated antiviral signaling by deubiquitylating TRIM25.

Pauli EK, Chan YK, Davis ME, Gableske S, Wang MK, Feister KF, Gack MU.

Sci Signal. 2014 Jan 7;7(307):ra3. doi: 10.1126/scisignal.2004577.

8.

Subcellular Localizations of RIG-I, TRIM25, and MAVS Complexes.

Sánchez-Aparicio MT, Ayllón J, Leo-Macias A, Wolff T, García-Sastre A.

J Virol. 2017 Jan 3;91(2). pii: e01155-16. doi: 10.1128/JVI.01155-16. Print 2017 Jan 15.

9.

Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction.

Gack MU, Kirchhofer A, Shin YC, Inn KS, Liang C, Cui S, Myong S, Ha T, Hopfner KP, Jung JU.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16743-8. doi: 10.1073/pnas.0804947105. Epub 2008 Oct 23.

10.

Quantitative proteomic analysis of the influenza A virus nonstructural proteins NS1 and NS2 during natural cell infection identifies PACT as an NS1 target protein and antiviral host factor.

Tawaratsumida K, Phan V, Hrincius ER, High AA, Webby R, Redecke V, Häcker H.

J Virol. 2014 Aug;88(16):9038-48. doi: 10.1128/JVI.00830-14. Epub 2014 Jun 4.

11.

Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production.

Nistal-Villán E, Gack MU, Martínez-Delgado G, Maharaj NP, Inn KS, Yang H, Wang R, Aggarwal AK, Jung JU, García-Sastre A.

J Biol Chem. 2010 Jun 25;285(26):20252-61. doi: 10.1074/jbc.M109.089912. Epub 2010 Apr 20.

12.

Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responses.

Santiago FW, Covaleda LM, Sanchez-Aparicio MT, Silvas JA, Diaz-Vizarreta AC, Patel JR, Popov V, Yu XJ, García-Sastre A, Aguilar PV.

J Virol. 2014 Apr;88(8):4572-85. doi: 10.1128/JVI.03021-13. Epub 2014 Jan 29.

13.

Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection.

Oshiumi H, Matsumoto M, Hatakeyama S, Seya T.

J Biol Chem. 2009 Jan 9;284(2):807-17. doi: 10.1074/jbc.M804259200. Epub 2008 Nov 18.

14.

Linear ubiquitin assembly complex negatively regulates RIG-I- and TRIM25-mediated type I interferon induction.

Inn KS, Gack MU, Tokunaga F, Shi M, Wong LY, Iwai K, Jung JU.

Mol Cell. 2011 Feb 4;41(3):354-65. doi: 10.1016/j.molcel.2010.12.029.

15.

Ubiquitin-mediated modulation of the cytoplasmic viral RNA sensor RIG-I.

Oshiumi H, Matsumoto M, Seya T.

J Biochem. 2012 Jan;151(1):5-11. doi: 10.1093/jb/mvr111. Epub 2011 Sep 2. Review.

PMID:
21890623
16.

The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination.

Hu Y, Li W, Gao T, Cui Y, Jin Y, Li P, Ma Q, Liu X, Cao C.

J Virol. 2017 Mar 29;91(8). pii: e02143-16. doi: 10.1128/JVI.02143-16. Print 2017 Apr 15.

17.

The influenza virus NS1 protein as a therapeutic target.

Engel DA.

Antiviral Res. 2013 Sep;99(3):409-16. doi: 10.1016/j.antiviral.2013.06.005. Epub 2013 Jun 21. Review.

18.

Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells.

Pothlichet J, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM.

PLoS Pathog. 2013;9(4):e1003256. doi: 10.1371/journal.ppat.1003256. Epub 2013 Apr 11.

19.

Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus.

Mibayashi M, Martínez-Sobrido L, Loo YM, Cárdenas WB, Gale M Jr, García-Sastre A.

J Virol. 2007 Jan;81(2):514-24. Epub 2006 Nov 1.

20.

NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I.

Guo Z, Chen LM, Zeng H, Gomez JA, Plowden J, Fujita T, Katz JM, Donis RO, Sambhara S.

Am J Respir Cell Mol Biol. 2007 Mar;36(3):263-9. Epub 2006 Oct 19.

PMID:
17053203

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